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(Faculty Division of Natural Sciences Research Group of Biological Sciences)｜Researchers' Profile Teacher performance management system

HORI Sayaka

Faculty Division of Natural Sciences Research Group of Biological SciencesAssociate Professor
Last Updated :2025/06/24

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Profile Information

  • Profile

    Optimization of the types and timing of avoidance behaviors depending on the intensity of a noxious stimulus is essential for survival; however, processing in the central nervous system and its developmental bases are largely unknown. We had reported that Caenorhabditis elegans preferentially selects one of three different types of avoidance behaviors depending on the strength of the noxious stimulus. We screened 279 neuronal transcription factors using a combination of optogenetics and RNA interference methods and identified 19 candidates required for avoidance behaviors. Our study will provide a novel molecular basis to specify the synaptic functions for complex behavior.

  • Name (Japanese)

    Hori

  • Name (Kana)

    Sayaka

Degree

  • Doctor of Science, The University of Tokyo, Mar. 2007
  • Bachelor of Pharmaceutical Science, The University of Tokyo, Mar. 2002
  • Master of Science, The University of Tokyo, Mar. 2004

Research Interests

  • C. elegans
  • Comparative psychology
  • Sex difference
  • 動物行動学
  • 行動生理学
  • 包括脳ネットワーク
  • 分子生物学

Research Areas

  • Life sciences, Physiology
  • Life sciences, Animals: biochemistry, physiology, behavioral science
  • Life sciences, Neuroscience - general

Research History

  • Apr. 2023 - Present, Nara Women's University, 研究院自然科学系生物科学領域, Associate Professor
  • Apr. 2021 - Mar. 2023, 東京女子医科大学 看護専門学校, 非常勤講師（兼務）
  • Apr. 2021 - Mar. 2023, Tokyo Women's Medical University, Center for Medical and Nursing Education, Division of Basic Sciences, Senior Lecturer
  • Oct. 2018 - Mar. 2021, Tokyo Women's Medical University School of Medicine, Department of Physiology, Senior Lecturer
  • Jan. 2010 - Sep. 2018, Tokyo Women's Medical University, Faculty of Medicine, Faculty of Medicine, 助教
  • Oct. 2007 - Dec. 2009, 海洋研究開発機構 極限環境生物圏研究センター（海洋・極限環境生物圏領域）, ポストドクトラル研究員
  • Apr. 2007 - Oct. 2007, 東京大学 大学院理学系研究科 生物科学専攻 細胞生理化学研究室, 産学官連携研究員
  • Mar. 2007, The University of Tokyo, Graduate School of Science, Department of Biological Sciences, 博士（理学)
  • Mar. 2004, The University of Tokyo, Graduate School of Science, Department of Biological Sciences
  • Mar. 2002, The University of Tokyo, Faculty of Pharmaceutical Sciences
  • Apr. 1998, The University of Tokyo, College of Arts and Sciences

Education

  • Apr. 2004 - Mar. 2007, The University of Tokyo, 大学院理学系研究科 生物科学専攻 博士後期課程
  • Apr. 2002 - Mar. 2004, The University of Tokyo, 大学院理学系研究科 生物科学専攻 修士課程
  • Apr. 2000 - Mar. 2002, The University of Tokyo, 薬学部
  • Apr. 1998 - Mar. 2000, The University of Tokyo, 教養学部理科II類
  • Apr. 1995 - Mar. 1998, 熊本県立熊本高等学校, 普通科

Teaching Experience

  • Jul. 2024 - Present
  • Jul. 2024 - Present
  • Jun. 2024 - Present
  • Apr. 2024 - Present
  • Apr. 2024 - Present
  • Apr. 2024 - Present
  • Apr. 2024 - Present
  • 行動生理学セミナーⅡ, Nara Women's University, Oct. 2023 - Present
  • 行動生理学演習Ⅰ, Nara Women's University, Oct. 2023 - Present
  • Practical Exercises on Biological and Environmental SciencesII, Nara Women's University, Oct. 2023 - Present
  • Biodiversity Laboratory 2, Nara Women's University, Oct. 2023 - Present
  • Animal Morphology and Histology, Nara Women's University, Oct. 2023 - Present
  • Oct. 2023 - Present
  • Topics in Molecular and Cellular Biology 8, Nara Women's University, Jun. 2023 - Present
  • Topics in Functional Biology of Multicellular Organisms 1, Nara Women's University, May 2023 - Present
  • 行動生理学演習Ⅳ, Nara Women's University, Apr. 2023 - Present
  • 行動生理学セミナーⅠ, Nara Women's University, Apr. 2023 - Present
  • Biology of Homeostasis, Nara Women's University, Apr. 2023 - Present
  • 行動生理学特論, Nara Women's University, Apr. 2023 - Present
  • Apr. 2022 - Mar. 2023
  • Apr. 2022 - Mar. 2023
  • Jan. 2022 - Mar. 2023
  • Apr. 2021 - Mar. 2023
  • Apr. 2021 - Mar. 2023

Professional Memberships

  • 公益財団法人 大隅基礎科学創成財団 研究者会員
    Mar. 2022 - Present
  • 日本神経科学学会
    Present
  • 日本分子生物学会
    Present
  • 日本動物学会
    Present
  • 東京女子医科大学学会
    Jan. 2020 - Mar. 2023
  • 東京女子医科大学 准教授会
    Oct. 2018 - Mar. 2021
  • 包括脳ネットワーク
  • 社会性昆虫コンソーシアム

Social Activities

  • 24 Nov. 2024 - 24 Nov. 2024
  • 22 Aug. 2024 - 22 Aug. 2024
  • 16 Mar. 2024 - 17 Mar. 2024, 45551025;45551019, rm:research_project_id
    対象リソースIRI
  • 2024 - 03 Feb. 2024, 40218121, rm:research_project_id
    対象リソースIRI
  • 10 Sep. 2022 - 10 Sep. 2022
  • 31 Aug. 2013 - 31 Aug. 2013
  • 05 Jul. 2007 - 05 Jul. 2007
  • 2007

Media Coverage

  • 『クラブ賞に堀准教授 「国際ソロプチミスト奈良」』, Other than myself, 奈良新聞, 奈良新聞, 02 Jan. 2025, 社会面, Paper

Academic Activities

  • nFuture Organizer, Academic society etc, 堀川誠,堀沙耶香,酒井奈緒子,倉持昌弘,小川貴史,新海陽一, 01 Mar. 2025 - 21 Aug. 2025

Other

  • Outstanding Poster Presentation Award（Establishment of a Simple Behavior Analysis Method Using a Paintbrush), Aug. 2024 - Aug. 2024
  • サイエンスチャンネルの科学番組「バクテリア その不思議な世界 」において、実験を行う研究者役として出演しています。, Oct. 2007 - Oct. 2007
  • Jul. 2007 - Jul. 2007
  • Mar. 2004 - Mar. 2004

■Ⅱ．研究活動実績

Published Papers

  • Refereed, Zoological Letters, Springer Science and Business Media LLC, Male Caenorhabditis elegans optimizes avoidance behavior against acute and chronic stress for successful mating with hermaphrodites, Sayaka Hori; Shohei Mitani, Abstract

    The optimization of avoidance behaviors in response to stress is an instinctual life function universally present in animals. In many sexually dimorphic animals, males exhibit higher stress resistance than females, but there have been no reports of comparative studies on stress resistance in sexually dimorphic hermaphrodites capable of reproducing alone. In the present study, we aimed to utilize a reversal/turn behavioral choice to conduct a comparative analysis of optimized avoidance behavior patterns in hermaphrodite and male Caenorhabditis elegans. We found that C. elegans males showed greater resistance to physical movement under acute stress and to lifespan reduction under chronic stress than C. elegans hermaphrodites. Interestingly, males exhibited a stronger avoidance behavior pattern known as “turn” than did the hermaphrodites, even in response to mild acute stress stimuli, to which they responded as if they had been exposed to strong stimuli. Stress conditions can lead to unsuccessful mating in C. elegans, and exaggerated stress avoidance in males may have biological significance for successful mating. This sexual dimorphism in avoidance behavior optimization was attributed to neural circuits downstream of the AIB neurons, the center of turn behavior, suggesting the presence of a novel mechanism distinct from previously reported neural and molecular mechanisms of avoidance behavior optimization., 17 Apr. 2025, 11, 4, Scientific journal, 10.1186/s40851-025-00250-7
    URLDOI URL
  • Refereed, microPublication Biology, An atonal homolog, lin-32, regulates hypodermal morphogenesis in Caenorhabditis elegans, Sayaka Hori; Shohei Mitani, 14 Feb. 2023, 10.17912/micropub.biology.000754., Scientific journal, 10.17912/micropub.biology.000754.
    DOI URL
  • Refereed, Scientific reports, The transcription factor unc-130/FOXD3/4 contributes to the biphasic calcium response required to optimize avoidance behavior., Sayaka Hori; Shohei Mitani, The central neural network optimizes avoidance behavior depending on the nociceptive stimulation intensity and is essential for survival. How the property of hub neurons that enables the selection of behaviors is genetically defined is not well understood. We show that the transcription factor unc-130, a human FOXD3/4 ortholog, is required to optimize avoidance behavior depending on stimulus strength in Caenorhabditis elegans. unc-130 is necessary for both ON responses (calcium decreases) and OFF responses (calcium increases) in AIBs, central neurons of avoidance optimization. Ablation of predicted upstream inhibitory neurons reduces the frequency of turn behavior, suggesting that optimization needs both calcium responses. At the molecular level, unc-130 upregulates the expression of at least three genes: nca-2, a homolog of the vertebrate cation leak channel NALCN; glr-1, an AMPA-type glutamate receptor; and eat-4, a hypothetical L-glutamate transmembrane transporter in the central neurons of optimization. unc-130 shows more limited regulation in optimizing behavior than an atonal homolog lin-32, and unc-130 and lin-32 appear to act in parallel molecular pathways. Our findings suggest that unc-130 is required for the establishment of some AIB identities to optimize avoidance behavior., 03 Feb. 2022, 12, 1, 1907, 1907, Scientific journal, True, 10.1038/s41598-022-05942-0
    DOI URL
  • Not Refereed, Feb. 2022, Research institution
  • Refereed, PLoS Genetics, OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses, Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, Jun. 2018, 14, 6, e1007477, Scientific journal, 10.1371/journal.pgen.1007477
    DOI URL
  • Refereed, Cell Reports, Elsevier B.V., An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans, Katsufumi Dejima; Sayaka Hori; Satoru Iwata; Yuji Suehiro; Sawako Yoshina; Tomoko Motohashi; Shohei Mitani, 02 Jan. 2018, 22, 1, 232, 241, Scientific journal, 10.1016/j.celrep.2017.12.024
    DOI URL
  • Refereed, Micropublication: biology, Novel deletion alleles of a C. elegans gene Y48E1C.1, named as tm5468, tm5625 and tm5626, Hori, S; Suehiro, Y; Yoshina, S; Mitani S, Oct. 2017, https://doi.org/10.17912, /W2CQ1, Scientific journal
  • Refereed, Jun. 2017, 79, 3, 44, 48
  • Not Refereed, Feb. 2017, Research institution
  • Refereed, Micropublication: biology, Novel deletion alleles of a C. elegans gene Y73E7A.1, named as tm6429 and tm6475. Micropublication, Suehiro, Y; Yoshina, S; Hori, S; Mitani, S, 2017, https://doi.org/10.17912/W2HH3, Scientific journal
  • Refereed, Micropublication: biology, Novel deletion alleles of a C. elegans gene C38D4.9, named as tm4476 and tm4561., Yoshina S; Hori, S; Suehiro, Y; Mitani, S, 2017, https://doi.org/10.17912/W2808, Scientific journal
  • Refereed, SCIENTIFIC REPORTS, Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9, Satoru Iwata; Sawako Yoshina; Yuji Suehiro; Sayaka Hori; Shohei Mitani, Sep. 2016, 6, 33840, Scientific journal, 10.1038/srep33840
    DOI URL
  • Refereed, ELIFE, The DEG/ENaC Cation Channel Protein UNC-8 Drives Activity-Dependent Synapse Removal in Remodeling GABAergic Neurons, Tyne W. Miller-Fleming; Sarah C. Petersen; Laura Manning; Cristina Matthewman; Megan Gornet; Allison Beers; Sayaka Hori; Shohei Mitani; Laura Bianchi; Janet Richmond; David M. Miller, Jul. 2016, 5, e14599, e14599, Scientific journal, 10.7554/eLife.14599
    DOI URL
  • Not Refereed, Feb. 2016, Research institution
  • Refereed, PLOS ONE, A Conditional Knockout Toolkit for Caenorhabditis elegans Based on the Cre/loxP Recombination, Eriko Kage-Nakadai; Rieko Imae; Yuji Suehiro; Sawako Yoshina; Sayaka Hori; Shohei Mitani, Dec. 2014, 9, 12, e114680, Scientific journal, 10.1371/journal.pone.0114680
    DOI URL
  • Refereed, Nov. 2014, 34, 18, 19
  • Refereed, FRONTIERS IN MICROBIOLOGY, High frequency of phylogenetically diverse reductive dehalogenase-homologous genes in deep subseafloor sedimentary metagenomes, Mikihiko Kawai; Taiki Futagami; Atsushi Toyoda; Yoshihiro Takaki; Shinro Nishi; Sayaka Hori; Wataru Arai; Taishi Tsubouchi; Yuki Morono; Ikuo Uchiyama; Takehiko Ito; Asao Fujiyama; Fumio Inagaki; Hideto Takami, Mar. 2014, 5, 80, 1, 15, Scientific journal, 10.3389/fmicb.2014.00080
    DOI URL
  • Nov. 2013, 33, 22, 23
  • Refereed, PloS one, 11, Correction: Novel Middle-Type Kenyon Cells in the Honeybee Brain Revealed by Area-Preferential Gene Expression Analysis., Kaneko K; Ikeda T; Nagai M; Hori S; Umatani C; Tadano H; Ugajin A; Nakaoka T; Paul RK; Fujiyuki T; Shirai K; Kunieda T; Takeuchi H; Kubo T, Nov. 2013, 8, 10.1371/annotation/1fa31a02-1b58-4361-98eb-5c213e5d5336
    DOI URL
  • Refereed, PLOS ONE, Novel Middle-Type Kenyon Cells in the Honeybee Brain Revealed by Area-Preferential Gene Expression Analysis, Kumi Kaneko; Tsubomi Ikeda; Mirai Nagai; Sayaka Hori; Chie Umatani; Hiroto Tadano; Atsushi Ugajin; Takayoshi Nakaoka; Rajib Kumar Paul; Tomoko Fujiyuki; Kenichi Shirai; Takekazu Kunieda; Hideaki Takeuchi; Takeo Kubo, Aug. 2013, 8, 8, e71732, Scientific journal, 10.1371/journal.pone.0071732
    DOI URL
  • Refereed, NEURON, Sensory Neuron Fates Are Distinguished by a Transcriptional Switch that Regulates Dendrite Branch Stabilization, Cody J. Smith; Timothy O'Brien; Marios Chatzigeorgiou; W. Clay Spencer; Elana Feingold-Link; Steven J. Husson; Sayaka Hori; Shohei Mitani; Alexander Gottschalk; William R. Schafer; David M. Miller, Jul. 2013, 79, 2, 266, 280, Scientific journal, 10.1016/j.neuron.2013.05.009
    DOI URL
  • Refereed, Bioscience, Biotechnology and Biochemistry, Active bacterial flora surrounding foraminifera (xenophyophorea) living on the deep-sea floor, Sayaka Hori; Masashi Tsuchiya; Shinro Nishi; Wataru Arai; Takao Yoshida; Hideto Takami, 2013, 77, 2, 381, 384, Scientific journal, 10.1271/bbb.120663
    DOI URL
  • Refereed, G3-GENES GENOMES GENETICS, Large-Scale Screening for Targeted Knockouts in the Caenorhabditis elegans Genome, Robert Barstead; Gary Moulder; Beth Cobb; Stephen Frazee; Diane Henthorn; Jeff Holmes; Daniela Jerebie; Martin Landsdale; Jamie Osborn; Cherilyn Pritchett; James Robertson; John Rummage; Ed Stokes; Malani Vishwanathan; Shohei Mitani; Keiko Gengyo-Ando; Osamu Funatsu; Sayaka Hori; Rieko Imae; Eriko Kage-Nakadai; Hiroyuki Kobuna; Etsuko Machiyama; Tomoko Motohashi; Muneyoshi Otori; Yuji Suehiro; Sawako Yoshina; Donald Moerman; Mark Edgley; Ryan Adair; B. J. Allan; Vinci Au; Iasha Chaudhry; Rene Cheung; Owen Dadivas; Simon Eng; Lisa Fernando; Angela Fisher; Stephane Flibotte; Erin Gilchrist; Allison Hay; Peter Huang; Rebecca Worsley Hunt; Christine Kwitkowski; Joanne Lau; Norris Lee; Lucy Liu; Adam Lorch; Candy Luck; Jason Maydan; Sheldon McKay; Angela Miller; Greg Mullen; Candice Navaroli; Sarah Neil; Rebecca Hunt-Newbury; Mikhaela Partridge; Jaryn Perkins; Anna Rankin; Greta Raymant; Nadereh Rezania; Alexandra Rogula; Bin Shen; Greg Stegeman; Angela Tardif; Jon Taylor; Mariana Veiga; Tina Wang; Rick Zapf, Nov. 2012, 2, 11, 1415, 1425, Scientific journal, 10.1534/g3.112.003830
    DOI URL
  • Aug. 2012, 32, 22, 23
  • Refereed, BMC BIOTECHNOLOGY, Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method, Eriko Kage-Nakadai; Hiroyuki Kobuna; Osamu Funatsu; Muneyoshi Otori; Keiko Gengyo-Ando; Sawako Yoshina; Sayaka Hori; Shohei Mitani, Jan. 2012, 12, 1, 1, Scientific journal, 10.1186/1472-6750-12-1
    DOI URL
  • Refereed, APIDOLOGIE, Expression of two microRNAs, ame-mir-276 and-1000, in the adult honeybee (Apis mellifera) brain, Sayaka Hori; Kumi Kaneko; Takeshi H. Saito; Hideaki Takeuchi; Takeo Kubo, Jan. 2011, 42, 1, 89, 102, Scientific journal, 10.1051/apido/2010032
    DOI URL
  • Refereed, PLOS ONE, In Situ Hybridization Analysis of the Expression of Futsch, Tau, and MESK2 Homologues in the Brain of the European Honeybee (Apis mellifera L.), Kumi Kaneko; Sayaka Hori; Mai M. Morimoto; Takayoshi Nakaoka; Rajib Kumar Paul; Tomoko Fujiyuki; Kenichi Shirai; Akiko Wakamoto; Satomi Tsuboko; Hideaki Takeuchi; Takeo Kubo, Feb. 2010, 5, 2, e9213, Scientific journal, 10.1371/journal.pone.0009213
    DOI URL
  • Refereed, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 11, [New approach toward understanding of neural basis of the honeybee "dance communication"], Kiya T; Hori S; Takeuchi H; Kubo T, Sep. 2008, 53, 11, 1368, 1374
  • Refereed, JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, Associative learning and discrimination of motion cues in the harnessed honeybee Apis mellifera L., Sayaka Hori; Hideaki Takeuchi; Takeo Kubo, Aug. 2007, 193, 8, 825, 833, Scientific journal, 10.1007/s00359-007-0234-x
    DOI URL
  • Refereed, Establishment of visual associative learning paradigm using harnessed honeybee and analysis of its visual cognitive capacities, Sayaka Hori, 22 Mar. 2007, Doctoral thesis
  • Refereed, Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 7, Associative visual learning, color discrimination, and chromatic adaptation in the harnessed honeybee Apis mellifera L., Sayaka Hori; Hideaki Takeuchi; Kentaro Arikawa; Michiyo Kinoshita; Naoko Ichikawa; Masami Sasaki; Takeo Kubo, Jul. 2006, 192, 7, 691, 700, Scientific journal, 10.1007/s00359-005-0091-4
    DOI URL
  • Refereed, GENES TO CELLS, GRIP1 tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1, A Nakata; T Ito; M Nagata; S Hori; K Sekimizu, Nov. 2004, 9, 11, 1125, 1135, Scientific journal, 10.1111/j.1365-2443.2004.00795.x

MISC

  • Not Refereed, 05 Sep. 2020
  • Not Refereed, 日本分子生物学会年会プログラム・要旨集(Web), atonal,math1ホモログの転写因子lin‐32は線虫C.elegansの逃避行動における介在神経の分化に必要, HORI SAYAKA; ODA SHIGEKAZU; SUEHIRO YUJI; IINO YUICHI; MITANI SHOHEI, 2013, 36th, 2P-0699 (WEB ONLY)
  • Not Refereed, 日本分子生物学会年会プログラム・要旨集(Web), 光遺伝学技術を利用した,侵害刺激からの逃避行動を規定する神経回路形成・遺伝子発現制御におけるbHLH型転写因子lin‐32の新機能の解析, HORI SAYAKA; ODA SHIGEKAZU; SUEHIRO YUJI; IINO YUICHI; MITANI SHOHEI, 2012, 35th, 1W11III-1 (WEB ONLY)
  • Not Refereed, NEUROSCIENCE RESEARCH, Novel screening of molecules deciding synaptic connections using behavior induced by Channelrhodopsin-2 in C. elegans, Sayaka Hori; Shohei Mitani, 2011, 71, E132, E133, Summary international conference, 10.1016/j.neures.2011.07.569
    DOI URL
  • Not Refereed, Analysis of the brain substructures using region-preferential genes of the honeybee, Dec. 2009, Summary national conference
  • Not Refereed, 第32回日本分子生物学会要旨集, Inactivation of alfa-proteobacteria and activation of gamma-proteobacteria induced by a new candidate genus Xenophyophores (giant foraminifera) at a depth 7111m in the Izu-Ogasawara Trench, Dec. 2009, Summary national conference
  • Not Refereed, 2009, 25, 35, 35
  • Not Refereed, Protein, nucleic acid and enzyme, New approach toward understanding of neural basis of the honeybee "dance communication", Sep. 2008, 53, 11, 1368, 1374
  • Not Refereed, FEBS JOURNAL, Identification and analysis of genes that are expressed strongly in the optic lobes in the honeybee brain, K. Kaneko; S. Hori; H. Takeuchi; R. K. Paul; T. Fujiyuki; K. Shirai; A. Wakamoto; T. Kubo, Jun. 2008, 275, 147, 147, Summary international conference
  • Not Refereed, 12 Mar. 2008, 52, 129, 129
  • Not Refereed, 02-040 Metagenomic analysis of deep subsurface core samples collected in an offing of the Shimokita Peninsula on the northwest Honshu, Japan(Soil ecosystem), Takami Hideto; Toyoda Atsushi; Itoh Tekehiko; Tsubouchi Taishi; Matsui Satomi; Hori Sayaka; Nishi Shinrou; Arai Wataru; Morono Yuki; Inagaki Fumio; Takai Ken, 2008, 24, 78, 78
  • Not Refereed, 09-161 Bacterial population based on 16SrRNA genes of deep subsurface core sample collected in an offing of the Simokita Peninsula(Classification/Phylogenetic analysis), Nishi Shinro; Toyoda Atsushi; Matsui Satomi; Tsubouchi Taishi; Hori Sayaka; Arai Wataru; Morono Yuki; Inagaki Fumio; Takai Ken; Takami Hideto, 2008, 24, 139, 139
  • Not Refereed, The 8th Japanese Drosophila Research Conference, Associative learning and discrimination of visual motion cues in the harnessed honeybees (Apis mellifera L), Hori, S; Takeuchi, H; Kubo, T, Jul. 2007, Summary international conference, 10.1007/s00359-007-0234-x
    DOI URL
  • Not Refereed, ZOOLOGICAL SCIENCE, Identification and analysis of genes that are expressed strongly in the optic lobes in the honeybee brain, Kumi Kaneko; Sayaka Hori; Hideaki Takeuchi; Rajib Paul; Tomoko Fujiyuki; Kenichi Shirai; Akiko Wakamoto; Takeo Kubo, Dec. 2006, 23, 12, 1191, 1191, Summary international conference
  • Not Refereed, 01 Mar. 2005, 49, 64, 64
  • Not Refereed, ZOOLOGICAL SCIENCE, Analysis of molecular basis of associative visual learning in the honeybee Apis mellifera L., Sayaka Hori; Hideaki Takeuchi; Kentaro Arikawa; Michiyo Kinoshita; Masami Sasaki; Naoko Ichikawa; Takeo Kubo, Dec. 2004, 21, 12, 1315, 1316, Summary international conference
  • Not Refereed, 01 Mar. 2004, 48, 114, 114
  • Not Refereed, 01 Mar. 2003, 47, 93, 93
  • Zoological science, Zoological Society of Japan, ASSOCIATIVE VISUAL LEARNING IN HONEYBEES APIS MELLIFERA L.(Physiology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan) :, Hori Sayaka; Takeuchi Hideaki; Sasaki Masami; Ichikawa Naoko; Kubo Takeo, 2003, 20, 12, 1587, 1587

Books etc

  • 蛋白質核酸酵素 2008年 09月号 [雑誌], 共立出版, 22 Aug. 2008, Not Refereed
    Amazon URL

Presentations

  • 04 Jun. 2025, 04 Jun. 2025 - 04 Jun. 2025
  • 26 Apr. 2025
  • Public discourse, 15 Mar. 2025
  • 20 Dec. 2024, 02 Dec. 2024 - 20 Dec. 2024
  • nFuture 2024, Establishment of a Simple Behavior Analysis Method Using a Paintbrush, 27 Aug. 2024, 27 Aug. 2024 - 28 Aug. 2024
  • Sayaka Hori, Future of the Nematodes Studies 2023, A prototype circuit model for sex differences in optimization of avoidance behavior, 18 Aug. 2023, 17 Aug. 2023 - 18 Aug. 2023
  • 03 Sep. 2021, 02 Sep. 2021 - 04 Sep. 2021
  • Sayaka Hori; Shohei Mitani, 23rd International C. elegans Conference（Online）, Contribution of a FOXD3/4 ortholog to optimization of avoidance behavior mediated by pre- and postsynaptic gene expression for a biphasic calcium response, 23 Jun. 2021, 21 Jun. 2021 - 24 Jun. 2021
  • 05 Sep. 2020, 04 Sep. 2020 - 05 Sep. 2020
  • 03 Dec. 2019
  • Sayaka Hori, Neuro2019, Forkhead box transcription factors determine pre-synaptic specificity and synaptic transmission efficiency of a strength-dependent sensory processing circuit, 25 Jul. 2019, False
  • 24 Jul. 2019
  • 01 Jun. 2019, False
  • Sayaka Hori; Shohei Mitani, 次世代脳冬のシンポジウム, Forkhead box transcription factors determine synaptic specificity of a strength-dependent sensory processing circuit, 13 Dec. 2018, False
  • 06 Dec. 2018
  • 28 Nov. 2018
  • Sayaka Hori; Shohei Mitani, Forkhead box D4 transcription factor homolog, unc-130, affects sensory processing depending on stimulus strength, 27 Jul. 2018, False
  • 26 Jul. 2018
  • 20 Jul. 2017
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, Neuroscience2017, A proneural Atonal defines sensory processing depending on stimulus strength via regulating electrical synapses, 20 Jul. 2017, False
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, 21th International C.elegans Conference, OFF-responding Interneurons Control Stimulus Strength-Dependent Sensory Processing, 23 Jun. 2017, True
  • Katsufumi Dejima; Sayaka Hori; Satoru Iwata; Sawako Yoshina; Yuji Suehiro; Tomoko Motohashi; Shohei Mitani, 21th International C.elegans Conference, Balancer chromosome toolkit for C. elegans., 21 Jun. 2017
  • 30 Nov. 2016
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, CeNeuro2016,, Transcription factor lin-32 is essential for synaptogenesis in AIB interneuron, sustained neck muscle contraction and aversive behavior,, 29 Jul. 2016, True
  • Iwata, S; Dejima, K; Hori, S; Yoshina, S; Suehiro, Y; Mitani S, 7th Asia-Pacific C. elegans meeting, Genetic engineering of chromosomal balancer toolkit for gene-clusters mediated by CRISPR/Cas9 in Caenorhabditis elegans, 25 Jun. 2016
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, Analysis of novel functions of an atonal homolog in aversive behavior and gap junction formation, 23 Mar. 2016, False
  • 01 Dec. 2015
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, Analysis of neural mechanisms in behavioral switch in response to stimulating strength, 28 Jul. 2015, False
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, C. elegans 2015 20th International Meeting, Transcription factor lin-32 is essential for synaptogenesis in AIB interneuron, sustained neck muscle contraction and aversive behavior, 28 Jun. 2015, True
  • 12 Dec. 2014, False
  • 25 Nov. 2014
  • 15 May 2014
  • Dec. 2013, False
  • 31 Aug. 2013, False
  • Tyne W Miller; Sarah C Petersen; Megan E Gornet; Ying Wang; Han Lu; Cristina Matthewman; Laura Bianchi; Janet E Richmond; Shohei Mitani; Sayaka Hori; David M Mille, 19th International C. elegans Meeting, The degenerin family ion channel UNC-8 promotes activity-dependent remodeling of GABAergic synapses in C. elegans., 28 Jun. 2013, True
  • S. Hori; S. Oda; Y. Suehiro; Y. Iino; S. Mitani, 19th International C. elegans Meeting, Combination of optogenetics and reverse genetics: novel behavior screening for regulators of neural differentiation, Jun. 2013
  • 15 May 2013
  • 11 Dec. 2012
  • Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, Novel function of bHLH transcriptional factor lin-32 in avoidance cir cuit in C. elegans., Dec. 2012
  • Sayaka Hori; Shohei Mitani, Neuroscience 2012, Novel function of bHLH transcriptional factor lin-32 in escape/avoidance circuit in C. elegans, Sep. 2012
  • 13 Dec. 2011, 13 Dec. 2011 - 16 Dec. 2011, False
  • Dec. 2011, False
  • Sayaka Hori; Shohei Mitani, Novel screening of molecules deciding synaptic connections using behavior induced by Channelrhodopsin-2 in C. elegans, Sep. 2011, False
  • Aug. 2011, False
  • 2010, False
  • 21 Nov. 2009
  • Sayaka Hori; Tsuchiya Masashi; Shinro Nishi; Wataru Arai; Takao Yoshida; Hideto Takami, International Symposium on Chemosynthesis-Based Ecosystems (4th CBE), Bacterial diversity surrounding a new candidate genes Xenophyophores (Foraminifera) discovered at a depth 7111m near the Boso Peninsula, 04 Jul. 2009, 29 Jun. 2009 - 03 Jul. 2009
  • Hori, S; Takeuchi, H; Kubo, T, Eighth International Congress of Neuroethology, Associative learning and discrimination of visual motion cues in harnessed honeybees, 2007, 22 Jul. 2007 - 27 Jul. 2007
  • 05 Jul. 2007, 05 Jul. 2007 - 06 Jul. 2007
  • Hori, S; Takeuchi, H; Kubo, T, SECOND EUROPEAN CONFERENCE OF APIDOLOGY, Associative visual learning, color discrimination, and chromatic adaptation in the harnessed honeybee, 11 Sep. 2006, 10 Sep. 2006 - 14 Sep. 2006
  • Sayaka Hori, Würzburg Biozentrum (Closed meeting), Würzburg University, Würzburg (Germany), Visual associative learning in the harnessed honeybee, 08 Sep. 2006, True
  • Hori, S, Closed meeting, Université Paul-Sabatier, Toulouse (France), Visual associative learning in the harnessed honeybee, Sep. 2006
  • 07 Mar. 2005
  • Feb. 2005
  • Oral presentation

Awards

  • Dec. 2024
  • Sep. 2024
  • Outstanding Poster Award, nFuture 2024, Aug. 2024, Establishment of a Simple Behavior Analysis Method Using a Paintbrush
  • Nest Leader Award, Future of the Nematodes Studies 2023, Sayaka Hori, Aug. 2023, A prototype circuit model for sex differences in optimization of avoidance behavior, 40218121, rm:research_project_id
    対象リソースIRI
  • Jun. 2022
  • Apr. 2021
  • Hori et al., 2006が重要論文として推薦されました。, Faculty of 1000, Sayaka Hori, 2006
  • Mar. 2004
  • 19th Kyushu High School Broadcasting Contest Kumamoto Prefecture Announcement Division Prize, NHK, Sayaka Hori, Nov. 1997
  • 18th Kyushu High School Broadcasting Contest Kumamoto Prefecture Announcement Division Prize, NHK, Sayaka Hori, Nov. 1996

Research Projects

  • Jun. 2025, Principal investigator, 雌雄同体と雄の性的二型をもつ動物のリスク回避戦略の行動性差の解析, 堀沙耶香, 公益社団法人 日本動物学会, 2025年度 茗原眞路子研究奨励助成金, 奈良女子大学
  • ダイバーシティ研究環境実現イニシアティブ（女性リーダー育成型）, Feb. 2025 - Mar. 2025, HJ2R06015, Principal investigator, 雄特有の逃避行動最適化の神経・分子機序の解明と基礎モデルの構築, 堀沙耶香,末廣勇司, 奈良女子大学, 令和６年度 奈良女子大学 女性研究者 大型共同研究支援経費（追加募集）, 奈良女子大学, rm:published_papers
    対象リソースIRI
  • Dec. 2024 - Mar. 2025, 未定, 令和６年度II期教育研究支援員制度, 国立大学法人奈良国立大学機構 奈良女子大学
  • Aug. 2024 - Mar. 2025, Principal investigator, Analysis of a prototype circuit model generating sexual dimorphism in avoidance behavior optimization, Sayaka Hori, 山田科学振興財団, 2024年度研究援助 女性活躍支援枠, 国立大学法人奈良国立大学機構 奈良女子大学, rm:published_papers
    対象リソースIRI
  • Oct. 2022 - Nov. 2024, 2200082, Principal investigator, A prototype synaptic circuit model of sex differences in optimization of avoidance behavior, 堀沙耶香; 辻野賢治, The Sumitomo Foundation, Basic Science Research Projects, 東京女子医科大学, 奈良女子大学, rm:awards
    対象リソースIRI
  • Aug. 2024, Principal investigator, 未定, 堀沙耶香, 国立大学法人奈良国立大学機構 奈良女子大学, 令和６年度研究スキルアップ経費, 国立大学法人奈良国立大学機構 奈良女子大学
  • Mar. 2024 - Mar. 2024, Coinvestigator, 遺伝子のはたらきをみてみよう, 堀沙耶香, 寄付金「関西科学塾」, rm:social_contribution
    対象リソースIRI
  • Mar. 2024 - Mar. 2024, Coinvestigator, 遺伝子のはたらきをみてみよう, 堀 沙耶香, 地域連携事業「サイエンス発信広場」, rm:social_contribution
    対象リソースIRI
  • Apr. 2023 - Mar. 2024, Principal investigator, 逃避行動最適化の性差と破綻の回路モデル, 国立大学法人奈良国立大学機構 奈良女子大学, 令和5年度 奈良女子大学研究推進プロジェクト経費, 国立大学法人奈良国立大学機構 奈良女子大学
  • Aug. 2023, Principal investigator, 令和5年度研究スキルアップ経費, 堀 沙耶香, 国立大学法人奈良国立大学機構 奈良女子大学, 国立大学法人奈良国立大学機構 奈良女子大学
  • May 2023, Principal investigator, 令和５年度II期教育研究支援員制度, 堀 沙耶香, 国立大学法人奈良国立大学機構 奈良女子大学
  • Apr. 2019 - Mar. 2023, Principal investigator, 逃避行動最適化の１神経細胞における神経応答のシナプス解剖学的解析, 堀沙耶香, 文部科学省, 科学研究費補助金 基盤研究(C), 4200000, 0, 0, Competitive research funding, rm:published_papers
    対象リソースIRI
  • Oct. 2020 - Mar. 2022, Principal investigator, Analysis of the molecular basis of the prototype circuit for optimization of avoidance behavior, Sayaka Hori, 公益財団法人 大隅基礎科学創成財団, Ohsumi Frontier Science Foundation, 東京女子医科大学, rm:published_papers
    対象リソースIRI
  • Apr. 2019 - Mar. 2020, Principal investigator, 行動最適化の原型回路をモデルとした精神疾患リスク因子のシナプス機能の解析, 堀沙耶香, 公益信託 成茂, 成茂神経科学研究助成基金, 500000, 500000, 0, Competitive research funding, rm:published_papers
    対象リソースIRI
  • Oct. 2018 - Mar. 2019, Principal investigator, 逃避行動様式の決定に関する分子遺伝学的研究, 堀沙耶香, 東京女子医科大学, 研究支援員制度, 1920000, 1920000, 0, Competitive research funding, rm:misc
    対象リソースIRI
  • Sep. 2016 - Mar. 2017, 高性能な線虫バランサーの整備, 三谷昌平, AMED, ナショナルバイオリソースプロジェクト 基盤技術整備プログラム, 6000000, 6000000, 0, 研究協力者として参加。, Competitive research funding
  • Apr. 2016 - Mar. 2017, Principal investigator, 逃避行動選択の鍵となる電気的シナプスの発生制御と神経回路基盤の解析, 堀沙耶香, 東京女子医科大学, 基礎研究振興費, 700400, 700400, 0, Competitive research funding
  • Apr. 2013 - Mar. 2016, Principal investigator, 逃避行動を規定する神経回路発生の分子機序の解析, Sayaka Hori, The Ministry of Education,Culuture,Sports,Science and Technology (MEXT), Grant-in-Aid for Young Scientists (B), 0, 0, 0, Competitive research funding
  • Apr. 2012 - Mar. 2015, 高浸透圧刺激への忌避行動を規定する転写因子群の分子・神経機能の研究, 三谷昌平, 私立大学等経常費補助金 大学間連携等による共同研究, 0, 0, 0, Competitive research funding
  • Apr. 2010 - Mar. 2011, Principal investigator, 行動変化を指標にした軸索投射を規定する分子基盤の網羅的スクリーニングと機能解析, 堀沙耶香, 東京女子医科大学, 基礎プール, 0, 0, 0, Competitive research funding
  • 2010 - 2011, Principal investigator, 人為的誘発行動を指標にしたシナプス選択性を規定する分子基盤のスクリーニングと機能解析, 堀 沙耶香, ナリシゲ, 成茂神経科学研究助成基金, 0, 0, 0, Competitive research funding
  • Grant-in-Aid for Scientific Research (B), 2008 - 2010, 20310124, Coinvestigator not use grants, Preparation method of environmental DNA sample for conservation of the genetic resource in the deep subsurface biosphere and analysis of biodiviersity harbored in the DNA, TAKAMI Hideto; HORI Sayaka; TSUBOUCHI Taishi; TOYODA Atsushi; HORI Sayaka; NISHI Shinro, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Japan Agency for Marine-Earth Science and Technology, 0, 0, 0, We attempted to extract environmental DNA mainly from ocean drilling core samples recovered offshore Shimokita Peninsula. The extracted DNA decreased with increasing of depth but the estimated cell number from DNA amount was not so different from those counted by microscopy. Thus, It is though that the DNA extraction method was almost successfully established. We also analyzed to figure out biodiversity based on 16S rDNA and the predicted metabolic potential from the identified genes in the DNA samples. JS1 and Chloroflexi were found to be predominant taxa as described previously up to a depth of 100m. In each DNA sample from different depth, 60,000-80,000 genes were identified. The sulfur respiration-related genes and methanogenesis-related genes were highlighted in sallower and deeper horizons, respectively., Competitive research funding, url
    対象リソースIRI
  • Grant-in-Aid for Young Scientists (Start-up), 2008 - 2009, 20810047, Principal investigator, Research of microbe in the deepest subsurface biosphere based on RNA analysis, HORI Sayaka, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Japan Agency for Marine-Earth Science and Technology, 0, 0, 0, To clarify bacterial diversity in the geological static deep-sea sediment, I tried to extract RNA to make cDNA libraries. The Automatic Bottom Inspection and Sampling Mobile "ABISMO" succeeded sampling at the deepest Mariana Trench, however, the included microbe was lower amount than previous report. Then, preliminary experiment was performed using the sediment in the static Izu-Ogasawara Trench. The population of Chloroflexi surrounding giant protist was significantly lower than the plain sediment, suggesting that bacteria in the activity state were distributed heterogeneously in the geologically static environment by coexistence with the large-sized creature., Competitive research funding, url
    対象リソースIRI
  • 2007, Principal investigator, 東京大学学術研究活動等奨励事業（国外）学術奨励費, 堀沙耶香, 東京大学, 東京大学学術研究活動等奨励事業（国外）学術奨励費, rm:presentations
    対象リソースIRI
  • 2007, Principal investigator, 堀沙耶香, 東京大学, 東京大学学術研究活動等奨励事業（国外）学術奨励費, 0, 0, 0, Competitive research funding

■Ⅲ．社会連携活動実績

１．公的団体の委員等（審議会、国家試験委員、他大学評価委員，科研費審査委員等）

  • 虫の集い, 線虫提供検討チーム, Feb. 2024 - Present, Society
  • JNS, Future Planning Committee - Member of Working Group for JNS Official Journals, Feb. 2020 - Present, Society
  • 奈良女子大学, オープンキャンパス委員, Apr. 2024 - Mar. 2026
  • 奈良女子大学, 広報委員, Apr. 2024 - Mar. 2026
  • 日本神経科学学会, 評議員, Apr. 2023 - Mar. 2026, Society
  • 奈良女子大学, 学年担任, Apr. 2024 - Mar. 2025
  • 東京女子医科大学, AI・データサイエンスと医療の委員会 委員, Apr. 2022 - Mar. 2023
  • 東京女子医科大学, 看護学部学友会特別会員, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 国家試験対策委員会, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 動物実験委員会, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 実験動物中央施設運営委員会, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, ICT(Information and Communication Technology) 委員, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 第１学年教育委員会, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 教学IR委員 支援員, Apr. 2021 - Mar. 2023
  • 東京女子医科大学, 数理データサイエンスAI教育プログラム 支援員, Dec. 2021 - Mar. 2022