Researchers Database

Takachi Ribeka

FacultyFaculty Division of Human Life and Environmental Sciences Research Group of Food Science and Nutrition
PositionProfessor
Last Updated :2022/10/06

researchmap

Profile and Settings

  • Name (Japanese)

    Takachi
  • Name (Kana)

    Ribeka

Degree

  • Master of Food and Nutritional Science, Tokyo University of Agriculture
  • Ph.D. in Medical Science, Tohoku University

Research Interests

  • 介入研究
  • 減塩
  • 食事評価システム開発
  • 栄養疫学
  • intervention study
  • dietary salt intake reduction
  • Development of automated self-administered dietary assessment system
  • Nutritional Epidemiology

Research Areas

  • Humanities & social sciences, Home economics, lifestyle science
  • Life sciences, Hygiene and public health (non-laboratory)

Education

  • 2009, Tohoku University, Graduate School of Medicine, 医科学専攻, Japan
  • 2005, Graduate School of Tokyo Univ. of Agriculture, 農学研究科, 食品栄養学専攻, Japan
  • 1994, Tokyo University of Agriculture, Faculty of Agriculture, 栄養学科, Japan

Ⅱ.研究活動実績

Published Papers

  • Refereed, Preventive Medicine, Elsevier BV, Association of sugary drink consumption with all-cause and cause-specific mortality: the Japan Public Health Center-based Prospective Study, Hsi-Lan Huang; Sarah Krull Abe; Norie Sawada; Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Taiki Yamaji; Hiroyasu Iso; Tetsuya Mizoue; Mitsuhiko Noda; Masahiro Hashizume; Manami Inoue; Shoichiro Tsugane, BACKGROUND: Few epidemiologic studies have assessed the associations of sugary drink consumption with mortality outcomes among Asian populations. METHODS: This study included 70,486 participants in the Japan Public Health Center-based Prospective Study at the age of 45-74 years in 1995-1999. A validated food frequency questionnaire was used to assess the consumption of sugary drinks. We estimated the risk of total and cause-specific mortality associated with sugary drink consumption using Cox proportional hazards regression model. RESULTS: Mean follow-up was 17.1 years, during which 11,811 deaths were documented. Sugary drink consumption was associated with higher total mortality, with multivariate HR of 1.06 (95% CI 1.00-1.13) for quintile 3, 1.07 (95% CI 1.01-1.13) for quintile 4, and 1.15 (95% CI 1.09-1.22) for quintile 5, compared with quintile 1 (P < 0.001 for trend). Additionally, positive associations with cause-specific mortality were observed, including death from circulatory system diseases (quintile 5 vs quintile 1; HR, 1.23; 95% CI 1.09-1.38) and heart disease (quintile 5 vs quintile 1; HR, 1.35; 95% CI 1.14-1.60). CONCLUSION: In this large Japanese prospective study, sugary drink consumption was associated with all-cause and cause-specific mortality., Jul. 2021, 148, 106561, 106561, Scientific journal, True
  • Refereed, Cancer Epidemiol Biomarkers Prev., Sugary drink consumption and subsequent colorectal cancer risk: the Japan Public Health Center-based Prospective Cohort Study, Leung CY; Abe SK; Sawada N; Ishihara J; Takachi R; Yamaji T; Iwasaki M; Hashizume M; Inoue M; Tsugane S, BACKGROUND: Most studies examining the associations of sugary drink consumption on colorectal cancer risk have been conducted in Western populations. METHODS: This study consisted of 74,070 participants in the Japan Public Health Center-based Prospective Study who completed a food frequency questionnaire (1995-1999). The participants were followed until December 2013 to investigate the associations between sugary drink consumption and colorectal cancer risk using Cox proportional hazards regression models. RESULTS: Among the 74,070 participants, mean age was 56.5 years at baseline, with a mean body mass index (BMI) of 23.5 and a mean daily consumption of 286 mL/day for men and 145 mL/day for women. During a follow-up of 15 years, 1,648 colorectal cancer cases were identified. No overall greater risk of colorectal cancer was observed among men [multivariable HR = 0.84; 95% confidence of interval (CI), 0.70-1.02; ≥254 mL/day vs. nonconsumers] and women (HR = 1.20; 95% CI, 0.96-1.50, ≥134 mL/day vs. nonconsumers). Sugary drink consumption was associated with colon cancer among women (HR = 1.36; 95% CI, 1.03-1.78, ≥134 mL/day vs. nonconsumers). HRs for proximal colon cancer among women who consumed sugary drinks, as compared with nonconsumers, were 1.47 (95% CI, 1.03-2.10) for sugary drink consumption less than 134 mL/day, and 1.45 (95% CI, 1.01-2.09) for at least 134 mL/day. CONCLUSIONS: In this large prospective cohort of Japanese with a moderate sugary drink consumption level and low prevalence of obesity, we observed a 36% increased risk of colon cancer in women. IMPACT: Our findings highlight the importance of subsite- and sex-specific investigation., Apr. 2021, 30, 4, 782, 8, Scientific journal, True
  • Refereed, 家政学研究, 食事調査に用いる料理データベース開発を目的とした男女・年代別の主食の飯および副菜の野菜類のポーションサイズの検討, 高地リベカ; 本多泉美; 石井有里; 丸谷幸子; 石原淳子; 髙田和子, Mar. 2021, 67, 2, 43, 9
  • Refereed, Geriatrics & Gerontology International, Wiley, Body mass index and risk of recurrent falls in community‐dwelling Japanese aged 40–74 years: The Murakami cohort study, Kazutoshi Nakamura; Kaori Kitamura; Yumi Watanabe; Keiko Kabasawa; Akemi Takahashi; Aya Hinata; Toshiko Saito; Ryosaku Kobayashi; Rieko Oshiki; Ribeka Takachi; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kei Watanabe, Jun. 2021, 21, 6, 498, 505, Scientific journal
  • Refereed, Nutrition Journal, Springer Science and Business Media LLC, Variations in the estimated intake of acrylamide from food in the Japanese population, Kumiko Kito; Junko Ishihara; Junpei Yamamoto; Takayuki Hosoda; Ayaka Kotemori; Ribeka Takachi; Kazutoshi Nakamura; Junta Tanaka; Taiki Yamaji; Taichi Shimazu; Yuri Ishii; Norie Sawada; Motoki Iwasaki; Hiroyasu Iso; Tomotaka Sobue; Shoichiro Tsugane, Dec. 2020, 19, 1, Scientific journal
  • Refereed, Nutrition Journal, Springer Science and Business Media LLC, Development and validation of nutrient estimates based on a food-photographic record in Japan, Keigo Saeki; Naoto Otaki; Maiko Kitagawa; Nobuhiro Tone; Ribeka Takachi; Rika Ishizuka; Norio Kurumatani; Kenji Obayashi, Abstract Background Previous studies have reported that estimates of portion size, energy, and macronutrients such as carbohydrates, proteins, and fat based on the food-photographic record closely correlate with directly weighed values. However, the correlation based on a large sample of the test meal with the evidence of many nutrients is yet to be determined. We conducted this study to assess the correlation and difference between the food-photographic record and weighed results for 44 nutrients based on a larger number of test meals than those in previous studies. Methods We assessed the nutrients of test meals using a food-photographic record and direct weighing and compared the results of the two methods. Twenty participants prepared a total of 1163 test meals. Each participant cooked 28–29 different kinds of dishes. Five participants cooked the same dish with their own recipes. For the most commonly consumed 41 dishes, 20 participants served a meal with their usual portion size. For the remaining 73 dishes, five participants served a meal with their usual portion size. An independent researcher weighed each ingredient and calculated the nutrients of the test meals. The participants took photographs of the test meals using a digital camera. Two independent, trained analysts measured the longitudinal and transverse diameters of the food area on the photographs of the test meals, compared the portion size with the reference photographs, and calculated the nutrients based on a database that contained reference photographs. Results Rank correlation coefficients between estimates from the food-photographic record of each test meal and weighed results were high for portion size (r = 0.93), energy (r = 0.93), protein (r = 0.90), fat (r = 0.92), and carbohydrate (r = 0.94), and those for the 44 nutrients ranged from 0.78 to 0.94. We found high reproducibility between the two analysts for all the nutrients (r > 0.90). Conclusions We found a high correlation and small difference between the food-photographic record method and weighed results of a large number of nutrients in many test meals., Dec. 2020, 19, 1, 104, Scientific journal
  • Refereed, PLOS ONE, Public Library of Science (PLoS), Association between meat intake and mortality due to all-cause and major causes of death in a Japanese population, Eiko Saito; Xiaohe Tang; Sarah Krull Abe; Norie Sawada; Junko Ishihara; Ribeka Takachi; Hiroyasu Iso; Taichi Shimazu; Taiki Yamaji; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, Purpose We examined the association between meat intake and mortality due to all-cause and major causes of death using a population-based cohort study in Japan. Methods 87,507 Japanese aged between 45 and 74 years old at 5-year follow-up study were followed for 14.0 years on average. Associations between meat intake and mortality risk were assessed using a Cox proportional hazards model. Results A heavy intake of total meat was associated with a higher risk of all-cause mortality relative to the lowest quartile intake in men (Q4: HR,1.18; 95%CIs, 1.06–1.31). A higher intake of total meat was associated with a lower risk of stroke mortality in women (Q2: HR, 0.70; 95%CIs, 0.51–0.94, Q3: HR, 0.68; 95%CIs, 0.50–0.95, Q4: HR, 0.66; 95%CIs, 0.44–0.99). A heavy intake of red meat was also associated with all-cause mortality (Q4: HR, 1.13; 95%CIs, 1.02–1.26) and heart disease mortality (Q4: HR, 1.51; 95%CIs, 1.11–2.06) in men but not in women. Heavy intake of chicken was inversely associated with cancer mortality in men. Conclusions Heavy intakes of total and red meat were associated with an increase in all-cause and heart disease mortality in men, while total meat intake was associated with a lower risk of stroke mortality in women. , Dec. 2020, 15, 12, e0244007, e0244007, Scientific journal
  • Refereed, Cancer Medicine, Wiley, Fermented and nonfermented soy foods and the risk of breast cancer in a Japanese population‐based cohort study, Ritsuko Shirabe; Eiko Saito; Norie Sawada; Junko Ishihara; Ribeka Takachi; Sarah Krull Abe; Taichi Shimazu; Taiki Yamaji; Atsushi Goto; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, BACKGROUND: Although preclinical studies suggest that fermented soy foods may have a protective effect against breast cancer, no prospective cohort studies have examined this association. OBJECTIVE: Our study examined the association between fermented and nonfermented soy food intake and breast cancer risk using a population-based prospective cohort study in Japan. METHODS: We included a total of 47,614 women aged 45-74 years in an analysis of the Japan Public Health Center-based Prospective Study (JPHC Study). A validated food frequency questionnaire (FFQ) was used for the assessment of dietary intake. Breast cancer incidence was analyzed by multivariate Cox proportional hazards regression models. RESULTS: During an average of 15.5 years of follow-up, 825 breast cancer cases were newly identified. We found no association of intake of soy foods with breast cancer risk, regardless of fermentation, with multivariate hazard ratios (HRs) and 95% confidence intervals (CIs) for the highest quartiles of fermented and nonfermented soy food intake of 0.94 (0.67, 1.32) and 1.15 (0.85, 1.57) compared with the lowest quartile (p for trend = 0.305 and 0.393). Unlike nonfermented soy, higher intake of fermented soy foods was associated with a significant decrease in the risk of nonlocalized breast cancer. The HR and 95% CI in the highest compared to lowest intake category of fermented soy foods was 0.53 (0.28, 0.99) versus nonfermented soy foods 0.85 (0.51, 1.42) (p for trend = 0.026 and 0.797). CONCLUSIONS: Our analyses showed that fermented soy foods had no association with overall breast cancer but may be associated with decreased risk of nonlocalized breast cancer., Dec. 2020, 10, 2, 757, 771, Scientific journal, True
  • Refereed, British Journal of Nutrition, Cambridge University Press (CUP), Predictors of decline in vitamin D status in middle-aged and elderly individuals: a 5-year follow-up study, Kazutoshi Nakamura; Kaori Kitamura; Yumi Watanabe; Toshiko Saito; Akemi Takahashi; Ryosaku Kobayashi; Rieko Oshiki; Keiko Kabasawa; Ribeka Takachi; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Kei Watanabe, AbstractLittle is known about predictors of decline in vitamin D status (vitamin D decline) over time. We aimed to determine demographic and lifestyle variables associated with vitamin D decline by sufficiently controlling for seasonal effects of vitamin D uptake in a middle-aged to elderly population. Using a longitudinal study design within the larger framework of the Murakami Cohort Study, we examined 1044 individuals aged between 40 and 74 years, who provided blood samples at baseline and at 5-year follow-up, the latter of which were taken on a date near the baseline examination (±14 d). Blood 25-hydroxyvitamin D (25(OH)D) concentrations were determined with the Liaison® 25OH Vitamin D Total Assay. A self-administered questionnaire collected demographic, body size and lifestyle information. Vitamin D decline was defined as the lowest tertile of 5-year changes in blood 25(OH)D (Δ25(OH)D) concentration (<6·7 nmol/l). Proportions of those with vitamin D decline were 182/438 (41·6 %) in men and 166/606 (27·4 %) in women (P < 0·0001). In men, risk of vitamin D decline was significantly lower in those with an outdoor occupation (P = 0·0099) and those with the highest quartile of metabolic equivalent score (OR 0·34; 95 % CI 0·14, 0·83), and higher in those with ‘university or higher’ levels of education (OR 2·92; 95 % CI 1·04, 8·19). In women, risk of vitamin D decline tended to be lower with higher levels of vitamin D intake (Pfor trend = 0·0651) and green tea consumption (Pfor trend = 0·0025). Predictors of vitamin D decline differ by sex, suggesting that a sex-dependent intervention may help to maintain long-term vitamin D levels., 14 Oct. 2020, 124, 7, 729, 735, Scientific journal, True
  • Refereed, Nutrients, MDPI AG, Short-Term Effects of Salt Restriction via Home Dishes Do Not Persist in the Long Term: A Randomized Control Study, Sachiko Maruya; Ribeka Takachi; Maki Kanda; Misako Nakadate; Junko Ishihara, Salt intake reduction is crucial to prevent non-communicable diseases (NCDs) globally. This study aimed to investigate the short- and long-term effects of monitoring salt concentration in homemade dishes on reducing salt intake in a Japanese population. A double-blind randomized controlled trial using a 2 × 2 factorial design with two interventions was conducted in 195 participants; they were assigned to both interventions for a group monitoring salt concentration in soups (control: no monitoring) and a group using low-sodium seasoning (control: regular seasoning). We evaluated 24-hour urinary sodium excretions at baseline and after a three-month intervention for the changes as major outcomes, at six- and twelve-months after baseline as long-term follow-up surveys. Urinary sodium excretion decreased in both intervention and control groups after the intervention. However, differences in the change for both monitoring and low-sodium seasoning interventions were statistically non-significant (p = 0.29 and 0.52, respectively). Urinary sodium excretion returned to the baseline level after twelve-months for all groups. Monitoring of salt concentration is ineffective in reducing salt intake for short- and long-term among the people studied in this cohort., Oct. 2020, 12, 10, 3034, 3034, Scientific journal
  • Refereed, European Journal of Nutrition, Springer Science and Business Media LLC, Comparison between the impact of fermented and unfermented soy intake on the risk of liver cancer: the JPHC Study, Sarah Krull Abe; Norie Sawada; Junko Ishihara; Ribeka Takachi; Nagisa Mori; Taiki Yamaji; Taichi Shimazu; Atsushi Goto; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, PURPOSE: The aim of this study was to compare the impact of fermented and unfermented soy intake, based on the following soy-derived products: tofu, soymilk, natto, and miso, on the risk of liver cancer among Japanese adults. METHODS: 75,089 Participants of the Japan Public Health Center-based Prospective Study (JPHC Study) were followed from the time of the 5-year follow-up questionnaire until the end of 2012-2013. Subjects with available data on hepatitis B virus (HBV) and hepatitis C virus (HCV) infection status from blood samples (n = 14,016) and those who were anti-HCV antibody (anti-HCV) or hepatitis B virus antigen (HBsAg) positive (n = 1033) were also analyzed separately. Cox proportional hazard models were employed to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs). RESULTS: During 1,145,453 person-years, 534 newly diagnosed cases of liver cancer were identified in the JPHC Study. For miso intake among men, the multivariate-adjusted highest versus lowest quartile HR was 0.65 (95% CI, 0.48-0.89); p for trend = 0.006. Results were similar in those who were anti-HCV or HBsAg positive, 0.24 (0.08-0.70); p for trend = 0.004 highest versus lowest tertile. For the sub-analysis among only participants with known hepatitis infection status and HCV and HBsAg adjustment, a similar association was observed. In the multivariate complete cohort analysis, among women, the highest intake of fried tofu was inversely associated with the risk of liver cancer, HR = 0.45 (0.26-0.80); p for trend = 0.014. CONCLUSIONS: We observed no association between total soy intake, fermented and unfermented, and risk of liver cancer, and only an inverse association between miso intake and liver cancer among men., 27 Jul. 2020, 60, 3, 1389, 1401, Scientific journal, True
  • Refereed, Cancer Epidemiology Biomarkers & Prevention, American Association for Cancer Research (AACR), Soy Food Intake and Pancreatic Cancer Risk: The Japan Public Health Center–based Prospective Study, Yoko Yamagiwa; Norie Sawada; Taichi Shimazu; Taiki Yamaji; Atsushi Goto; Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, BACKGROUND: Although the poor prognosis and increasing incidence of pancreatic cancer highlight the need for prevention strategies, few lifestyle risk factors for pancreatic cancer have yet been identified. Soybeans contain various bioactive compounds. However, the association between soy food intake and pancreatic cancer risk remains unknown. METHODS: The Japan Public Health Center-based Prospective Study is a cohort study conducted in a general Japanese population. To determine the association of soy food intake and pancreatic cancer incidence, we analyzed 90,185 participants who responded to a questionnaire on medical history and lifestyle factors, including dietary factors based on a food frequency questionnaire in 1995-1998, using Cox proportional hazards models. RESULTS: During a median follow-up of 16.9 years, 577 cases of pancreatic cancer were identified. In the multivariate-adjusted model, total soy food intake was statistically significantly associated with an increased risk of pancreatic cancer [HR for the highest vs. lowest intake quartile: 1.48; 95% confidence interval (CI), 1.15-1.92; Ptrend = 0.007]. Among soy foods, nonfermented soy food intake showed a statistically significant positive association with pancreatic cancer (HR, 1.41; 95% CI, 1.09-1.81; Ptrend = 0.008), whereas fermented soy food intake showed no association (HR, 0.96; 95% CI, 0.73-1.26; Ptrend = 0.982). CONCLUSIONS: Higher intake of soy foods, particularly nonfermented soy foods, might increase pancreatic cancer risk. IMPACT: This study is the first to report an association between the intake of various soy foods and pancreatic cancer risk. Further studies are required to confirm our findings., Jun. 2020, 29, 6, 1214, 1221, Scientific journal, True
  • Refereed, British Journal of Nutrition, Cambridge University Press (CUP), Dietary calcium and vitamin K are associated with osteoporotic fracture risk in middle-aged and elderly Japanese women, but not men: the Murakami Cohort Study, Kseniia Platonova; Kaori Kitamura; Yumi Watanabe; Ribeka Takachi; Toshiko Saito; Keiko Kabasawa; Akemi Takahashi; Ryosaku Kobayashi; Rieko Oshiki; Aleksandr Solovev; Masayuki Iki; Shoichiro Tsugane; Ayako Sasaki; Osamu Yamazaki; Kei Watanabe; Kazutoshi Nakamura, Abstract Although dietary Ca, vitamin D and vitamin K are nutritional factors associated with osteoporosis, little is known about their effects on incident osteoporotic fractures in East Asian populations. This study aimed to determine whether intakes of these nutrients predict incident osteoporotic fractures. We adopted a cohort study design with a 5-year follow-up. Subjects were 12 794 community-dwelling individuals (6301 men and 6493 women) aged 40–74 years. Dietary intakes of Ca, vitamin D and vitamin K were assessed with a validated FFQ. Covariates were demographic and lifestyle factors. All incident cases of major osteoporotic limb fractures, including those of the distal forearm, neck of humerus, neck or trochanter of femur and lumbar or thoracic spine were collected. Hazard ratios (HR) for energy-adjusted Ca, vitamin D and vitamin K were calculated with the residual method. Mean age was 58·8 (sd 9·3) years. Lower energy-adjusted intakes of Ca and vitamin K in women were associated with higher adjusted HR of total fractures (Pfor trend = 0·005 and 0·08, respectively). When vertebral fracture was the outcome, Pfor trend values for Ca and vitamin K were 0·03 and 0·006, respectively, and HR of the lowest and highest (reference) intake groups were 2·03 (95 % CI 1·08, 3·82) and 2·26 (95 % CI 1·19, 4·26), respectively. In men, there were null associations between incident fractures and each of the three nutrient intakes. Lower intakes of dietary Ca and vitamin K were independent lifestyle-related risk factors for osteoporotic fracture in women but not men. These associations were robust for vertebral fractures, but not for limb fractures., 07 May 2020, 1, 10, Scientific journal
  • Refereed, European Journal of Nutrition, Springer Science and Business Media LLC, Associations between changes in fruit and vegetable consumption and weight change in Japanese adults, Calistus Wilunda; Norie Sawada; Atsushi Goto; Taiki Yamaji; Ribeka Takachi; Junko Ishihara; Nagisa Mori; Ayaka Kotemori; Motoki Iwasaki; Shoichiro Tsugane, BACKGROUND: Fruits and vegetables may induce greater satiety, reduce hunger, decrease energy intake, and modulate energy metabolism, thereby playing a role in weight loss. OBJECTIVE: To determine the associations between changes in fruit and vegetable consumption and weight change over a 5-year interval in Japanese adults. METHODS: This cohort study included 54,015 subjects (54.6% female, mean age 56.5 years) of the Japan Public Health Center-based Prospective Cohort Study who had no known history of major chronic diseases at baseline. Data on fruit and vegetable consumption were collected using a validated food frequency questionnaire. Body weight was self-reported. We used multivariable linear mixed-effects regression models to examine the associations between changes in fruit and vegetable consumption and change in body weight. RESULTS: On average, body weight decreased by 25 g [95% confidence interval (CI), 3, 47] for every 100 g/d increase in total vegetable consumption. Change in fruit consumption was nonlinearly associated with weight change. Fruit consumption was directly associated with weight change among subjects who increased consumption (70 g; 95% CI, 39, 101) but was not associated with weight change among subjects who reduced or did not change fruit consumption. These associations did not vary by sex, age, and body mass index (BMI) at baseline. The association with vegetables was restricted to yellow/red vegetables (- 74 g; 95% CI, - 129, - 18) and allium vegetables (- 129 g; 95% CI, - 231, - 28). Lower-fiber vegetables were inversely associated with weight change, whereas lower-fiber fruits or higher-energy fruits were directly associated with weight change beyond 0 g/d change in consumption. CONCLUSIONS: Change in vegetable consumption was inversely associated with weight change while fruit consumption was positively associated with weight change among subjects who increased consumption. The influence of fruits and vegetables on weight change may depend on the characteristics of the fruits and vegetables., 06 Apr. 2020, 60, 1, 217, 227, Scientific journal, True
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Study Design and Baseline Profiles of Participants in the Uonuma CKD Cohort Study in Niigata, Japan, Keiko Kabasawa; Junta Tanaka; Kazutoshi Nakamura; Yumi Ito; Kinya Yoshida; Ribeka Takachi; Norie Sawada; Shoichiro Tsugane; Ichiei Narita, BACKGROUND: Evidence for primary prevention of chronic kidney disease (CKD) is insufficient. The population-based prospective Uonuma CKD cohort study aims to explore associations of lifestyle and other risk factors with CKD. We report here the study design and baseline profiles. METHODS: All 67,322 residents aged ≥40 years in Minamiuonuma City, Uonuma City, and Yuzawa Town, Niigata Prefecture, Japan and 11,406 participants who attended local health-check examinations were targeted for baseline questionnaire and biochemical sampling, respectively. Information was gathered from 43,217 (64.2%) questionnaires and 8,052 (70.6%) biochemical samples; 6,945 participants consented to both questionnaire and biochemical sampling at baseline, conducted between fiscal years 2012 and 2015. Participants provided information regarding sociodemographic, lifestyle, and self-reported outcomes. Urine albumin-to-creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) were measured. The primary outcome is CKD based on self-report and biochemical/clinical diagnosis. RESULTS: Mean age of questionnaire respondents was 63.3 (standard deviation [SD], 12.5) years for men and 64.3 (SD, 13.3) years for women. Among participants who submitted urine samples, median ACR was 10.0 (interquartile range [IQR], 5.0-24.0) mg/g for men and 13.0 (IQR, 7.7-27.0) mg/g for women, and median eGFR was 73.6 mL/min/1.73 m2 (IQR, 63.5-84.5) for men and 73.5 mL/min/1.73 m2 (IQR, 64.4-83.5) for women. ACR 30 mg/g or more was found in 1,741 participants (21.7%) and eGFR <60 mL/min/1.73 m2 in 1,361 participants (16.9%). CONCLUSION: The Uonuma CKD cohort study was established to investigate the impact of lifestyle on CKD development and to provide data for preventing the onset and progression of CKD., 05 Apr. 2020, 30, 4, 170, 176, Scientific journal, False
  • Refereed, European Journal of Pain, Wiley, Total physical activity and risk of chronic low back and knee pain in middle‐aged and elderly Japanese people: The Murakami cohort study, Aleksandr Solovev; Yumi Watanabe; Kaori Kitamura; Akemi Takahashi; Ryosaku Kobayashi; Toshiko Saito; Ribeka Takachi; Keiko Kabasawa; Rieko Oshiki; Kseniia Platonova; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kei Watanabe; Kazutoshi Nakamura, BACKGROUND: Specific components of physical activity, such as vigorous exercise and heavy occupational work, are known to increase the risk of chronic low back pain (CLBP) and chronic knee pain (CKP), but impacts of other components are less known. This study aimed to assess the relationship between total physical activity and risk of CLBP and CKP from a public health perspective. METHODS: Participants were 7,565 individuals, aged 40-74 years, who did not have CLBP or CKP, and who participated in the 5-year follow-up survey. A self-administered questionnaire was used to obtain information on demographics, body size and lifestyle (including physical activity) in the baseline survey in 2011-2013, and on CLBP and CKP using Short Form 36 (SF-36) in the follow-up survey. Sitting, standing, walking and strenuous work for occupational activity were assessed for total physical activity, and walking slowly, walking quickly, light to moderate exercise and strenuous exercise were assessed for leisure-time physical activity using metabolic equivalent hours/day (METs score). RESULTS: Mean age of participants was 60.1 years (SD, 8.8). Participants with higher METs scores had a significantly higher risk of CKP (p for trend = 0.0089, OR of 4th quartile = 1.29, 95% CI: 1.04-1.59 vs. 1st quartile), but not CLBP. An intermediate leisure-time METs score was associated with a lower risk of CLBP (OR = 0.75, 95%CI: 0.61-0.92 vs. 0 METs-group). CONCLUSIONS: A high level of total physical activity may increase the risk of CKP, whereas an intermediate level of leisure-time physical activity may decrease the risk of CLBP, in middle-aged and elderly individuals. SIGNIFICANCE: Evidence on the longitudinal association between total physical activity and CLBP and CKP in middle-aged and elderly people is lacking. We conducted a cohort study to assess this association, and found that high levels of total physical activity increased risk of CKP, and intermediate levels of leisure-time physical activity decreased risk of CLBP. This suggests that the effect of physical activity on chronic pain differed by pain site., Apr. 2020, 24, 4, 863, 872, Scientific journal, True
  • Refereed, European Journal of Cancer Prevention, Ovid Technologies (Wolters Kluwer Health), Doneness preferences, meat and meat-derived heterocyclic amines intake, and N-acetyltransferase 2 polymorphisms: Association with Colorectal Adenoma in Japanese Brazilians., Sanjeev Budhathoki; Motoki Iwasaki; Taiki Yamaji; Gerson S. Hamada; Nelson T. Miyajima; Jose C. Zampieri; Sangita Sharma; Mohammadreza Pakseresht; Fariba Kolahdooz; Junko Ishihara; Ribeka Takachi; Hadrien Charvat; Loïic Le Marchand; Shoichiro Tsugane, Intake of heterocyclic amines (HCAs) and other mutagenic compounds formed during cooking has been hypothesized to be responsible for the positive association observed between red meat and colorectal cancer. We evaluated whether well-done/very well-done preferences for various meat and fish items, higher intakes of meat and fish, and meat-derived and fish-derived HCA are associated with the risk of colorectal adenoma (CRA) in a Japanese-Brazilian population. We selected 302 patients with adenoma and 403 control individuals who underwent total colonoscopy between 2007 and 2013, and collected information on aspects of meat intake using a detailed questionnaire. We also estimated HCA intake of the study participants using an HCA database that matched the cooking methods of this population. Latent class analysis on the basis of response to doneness preferences for different cooking methods of commonly consumed meat and fish items identified four distinct subgroups. Compared with the subgroup characterized by a preference for rare/medium well-done cooking for most meat and fish items, the odds ratio of CRA for the well-done/very well-done preference subgroup was 1.19 (95% confidence interval: 0.51-2.75). High intake of mixed-meat dishes was suggestively associated inversely with CRA, whereas a high intake of poultry was associated positively with CRA. No clear association with intake of total or specific HCAs and no effect modification by N-acetyltransferase 2 acetylation genotype were observed. We found no statistically significant associations between meat and HCA intake and CRA. These findings do not support a positive association between meat and meat-derived HCA intake and the risk of CRA., Jan. 2020, 29, 1, 7, 14, Scientific journal, True
  • Refereed, BMC Nephrology, Springer Science and Business Media LLC, Association of estimated dietary acid load with albuminuria in Japanese adults: a cross-sectional study, Keiko Kabasawa; Michihiro Hosojima; Ribeka Takachi; Kazutoshi Nakamura; Yumi Ito; Akihiko Saito; Norie Sawada; Shoichiro Tsugane; Junta Tanaka; Ichiei Narita, BACKGROUND: Acid-base imbalance might promote the progression of chronic kidney disease (CKD), but whether nutrient-derived dietary acid load increases the risk of albuminuria or even high normoalbuminuria is unclear. METHODS: A Japanese cohort comprising 3250 men and 3434 women aged 40-97 years with urine albumin-to-creatinine ratio (ACR) < 33.9 mg/mmol or estimated glomerular filtration rate ≥ 15 ml/min/1.73 m2 were assessed. We performed a cross-sectional evaluation of the association between net endogenous acid production (NEAP), estimated as dietary protein to potassium content ratio, and the presence of high normoalbuminuria (ACR: 1.13-3.38 mg/mmol) or microalbuminuria. RESULTS: Median NEAP was 43.4 (interquartile range (IQR): 34.2-53.4) mEq/day in men and 35.0 (IQR: 27.7-43.6) mEq/day in women. Median ACR was 1.11 (IQR: 0.57-2.49) mg/mmol in men and 1.47 (IQR: 0.82-2.83) mg/mmol in women. In multivariate analysis, the adjusted odds ratio of the highest versus lowest NEAP quartile for microalbuminuria was 1.47 (95% confidence interval (CI): 1.08-1.99) in men and 1.54 (95% CI: 1.11-2.14) in women. For high normoalbuminuria or microalbuminuria, the adjusted odds ratio was 1.28 (95% CI: 1.02-1.59) in men and 1.39 (95% CI: 1.11-1.74) in women. From nutrient composition analysis, subjects with the highest potassium intake, but not protein intake, had lower adjusted odds ratios for the presence of microalbuminuria than those in the lowest quartile for potassium intake. CONCLUSIONS: Higher NEAP was associated with albuminuria and its association might negatively relate to potassium intake in an adult Japanese population., Dec. 2019, 20, 1, 194, 194, Scientific journal, True
  • Refereed, JAMA Internal Medicine, American Medical Association (AMA), Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort, Sanjeev Budhathoki; Norie Sawada; Motoki Iwasaki; Taiki Yamaji; Atsushi Goto; Ayaka Kotemori; Junko Ishihara; Ribeka Takachi; Hadrien Charvat; Tetsuya Mizoue; Hiroyasu Iso; Shoichiro Tsugane, 01 Nov. 2019, 179, 11, 1509, 1509, Scientific journal
  • Refereed, Maturitas, Elsevier BV, Modifiable factors associated with symptomatic knee osteoarthritis: The Murakami cohort study, Ryoya Takiguchi; Rintaro Komatsu; Kaori Kitamura; Yumi Watanabe; Akemi Takahashi; Ryosaku Kobayashi; Rieko Oshiki; Toshiko Saito; Keiko Kabasawa; Ribeka Takachi; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kazutoshi Nakamura, Oct. 2019, 128, 53, 59, Scientific journal
  • Refereed, European Journal of Cancer Prevention, Ovid Technologies (Wolters Kluwer Health), Cruciferous vegetable intake and colorectal cancer risk, Nagisa Mori; Norie Sawada; Taichi Shimazu; Taiki Yamaji; Atsushi Goto; Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, We aimed to assess the association between cruciferous vegetable intake and colorectal cancer (CRC) development among Japanese adults aged between 45 and 74 years in the Japan Public Health Center-based Prospective Study. During 1 325 853 person-years of follow-up, 2612 CRC cases were identified. The association of cruciferous vegetable intake with CRC risk was assessed using a Cox proportional hazard regression model to compute hazard ratios (HRs) and 95% confidence intervals (CIs), adjusted for potential confounders. No significant association was observed between the highest cruciferous vegetable intake quartile (compared with the lowest) and CRC risk in men (multivariate HRs: 1.08; 95% CI: 0.91, 1.29) and women (multivariate HRs: 0.99; 95% CI: 0.80, 1.22) and its subsites. Women showed a marginal negative association between cruciferous vegetable intake and the risk of colon cancer (CC) after excluding participants who developed CC in the first 3 years of follow-up (P for trend = 0.08); a positive association was found with proximal CC in men. Cruciferous vegetable intake does not have a significant association with CRC risk in the Japanese general population., Sep. 2019, 28, 5, 420, 427, Scientific journal, True
  • Refereed, Open Access J Public Health., The effect of educational background music on reducing salt intake at a university canteen., Maruya S; Sato Y; Nakai H; Takachi R, Aug. 2019, 2, 4, 028, Scientific journal
  • Refereed, International Journal of Cancer, Wiley, Fruit and vegetable intake and pancreatic cancer risk in a population‐based cohort study in Japan, Yoko Yamagiwa; Norie Sawada; Taichi Shimazu; Taiki Yamaji; Atsushi Goto; Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Manami Inoue; Shoichiro Tsugane, Oxidative stress and chronic inflammation are potential pathogenic factors of pancreatic cancer. Although fruits and vegetables are abundant in antioxidants and anti-inflammatory constituents, the reported associations between fruit and vegetable intake and pancreatic cancer risk have been inconsistent. Here, we investigated the association between fruit and vegetable intake and pancreatic cancer risk as part of the Japan Public Health Center-based Prospective Study. The analysis included 90,185 participants who responded to a medical and lifestyle questionnaire during 1995-1998. Associations between fruit and vegetable intake and pancreatic cancer risk were evaluated with Cox proportional hazards models. Additional analyses were stratified by smoking status and body mass index. During follow-up (median duration, 16.9 years), 577 participants were diagnosed with pancreatic cancer. In multivariate-adjusted models, pancreatic cancer risk was inversely associated with total fruit intake (highest vs. lowest intake quartile; hazard ratio [HR]: 0.74, 95% confidence interval [CI]: 0.57-0.95, p-trend: 0.116) and positively associated with total vegetable intake (HR: 1.30, 95% CI: 1.01-1.66, p-trend: 0.151). For total fruit intake, the inverse association with pancreatic cancer risk was more apparent in never smokers (HR: 0.67, 95% CI: 0.47-0.97, p-trend: 0.034). For total vegetable intake, the positive association was statistically significant in ever smokers (HR: 1.49, 95% CI: 1.01-2.19, p-trend: 0.043) and statistically nonsignificant in never smokers. In summary, total fruit intake and total vegetable intake had inverse and positive associations, respectively, with pancreatic cancer risk. Vegetable intake may correlate with increased risk partly because of the influence of smoking on vegetable intake., 15 Apr. 2019, 144, 8, 1858, 1866, Scientific journal, True
  • Refereed, Clinical Nutrition, Elsevier BV, Cruciferous vegetable intake and mortality in middle-aged adults: A prospective cohort study, Nagisa Mori; Taichi Shimazu; Hadrien Charvat; Michihiro Mutoh; Norie Sawada; Motoki Iwasaki; Taiki Yamaji; Manami Inoue; Atsushi Goto; Ribeka Takachi; Junko Ishihara; Mitsuhiko Noda; Hiroyasu Iso; Shoichiro Tsugane, BACKGROUND & AIMS: Cruciferous vegetables contain isothiocyanates, which effectively reduce inflammation and oxidative stress related to chronic diseases, inhibit the bioactivation of procarcinogens, and enhance the excretion of carcinogens. However, at present, no large cohort studies have investigated the effect of cruciferous vegetable on mortality. We aimed to examine the association between cruciferous vegetable intake and all-cause mortality, namely cancer, heart disease, cerebrovascular disease, and injuries, in a large cohort study conducted between 1990 and 1993, in Japan. METHODS: The analysis included 88,184 participants (age: 45-74 years) with no history of cancer, myocardial infarction, and stroke. Participants were tracked for a median of 16.9 years, during which 15,349 deaths were occurred. The association between cruciferous vegetable intake and risk of all-cause and cause-specific mortality was determined by Cox proportional hazard regression analysis to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs), after adjustment for potential confounding factors. RESULTS: An inverse association was found between cruciferous vegetable intake and total mortality in both gender. HRs (95% CI) for all-cause mortality in the highest compared to the lowest quintile were 0.86 (0.80, 0.93) for men (P = 0.0002 for trend) and 0.89 (0.81, 0.98) for women (P = 0.03 for trend). Cruciferous vegetable intake was associated with lower cancer mortality in men, as well as with heart disease-, cerebrovascular disease-, and injury-related mortality in women. CONCLUSIONS: This prospective study suggests that a higher cruciferous vegetables intake is associated with reduced risk of all-cause mortality., Apr. 2019, 38, 2, 631, 643, Scientific journal, True
  • Refereed, Nutrients, MDPI AG, Validity and Reproducibility of a Self-Administered Food Frequency Questionnaire for the Assessment of Sugar Intake in Middle-Aged Japanese Adults, Rieko Kanehara; Atsushi Goto; Ayaka Kotemori; Nagisa Mori; Ari Nakamura; Norie Sawada; Junko Ishihara; Ribeka Takachi; Yukari Kawano; Motoki Iwasaki; Shoichiro Tsugane, We evaluated the validity and reproducibility of estimated sugar intakes using a food frequency questionnaire (FFQ) among middle-aged Japanese adults in the Japan Public Health Centre-Based Prospective (JPHC) study. In subsamples of the JPHC study (Cohorts I and II in multiple areas), we computed Spearman’s correlations of FFQ results with urine sugar concentrations and dietary records (DR) for validity; we evaluated correlations between two FFQs for reproducibility. During 1994–1998, participants (Cohort I: n = 27 [men], n = 45 [women]) provided two (spring and fall) 24-h urine samples and completed 7-consecutive-day DR per season (I: n = 99, n = 113; II: n = 168, n = 171) and two FFQs (147 food items) at yearly intervals (I: n = 101, n = 108; II: n = 143, n = 146). Sugar intakes from FFQ were correlated with urinary sugar (de-attenuated correlations: 0.40; 95%CI: 0.19, 0.58). After adjustment for sociodemographic and lifestyle variables, correlations between FFQ and DR for men and women were 0.57 (0.42, 0.69) and 0.41 (0.24, 0.55) (I) and 0.56 (0.44, 0.65) and 0.34 (0.20, 0.47) (II), respectively. Correlations between FFQs for men and women were 0.63 (0.49, 0.73) and 0.55 (0.41, 0.67) (I) and 0.66 (0.55, 0.74) and 0.63 (0.52, 0.72) (II). In conclusion, our study showed moderate FFQ validity and reproducibility for sugar intake evaluation., 05 Mar. 2019, 11, 3, 554, 554, Scientific journal
  • Refereed, Asia Pacific journal of clinical nutrition, Food frequency questionnaire reproducibility for middle-aged and elderly Japanese., Koutatsu Maruyama; Ai Ikeda; Junko Ishihara; Ribeka Takachi; Norie Sawada; Taichi Shimazu; Kazutoshi Nakamura; Junta Tanaka; Taiki Yamaji; Motoki Iwasaki; Hiroyasu Iso; Shoichiro Tsugane, BACKGROUND AND OBJECTIVES: The aim of this study was to examine the reproducibility of a self-administered food frequency questionnaire (FFQ) originally developed for the Japan Public Health Center-Based Prospective Study (JPHC study) and modified for use in the Next Generation (JPHC-NEXT) study. METHODS AND STUDY DESIGN: Participants included 98 men and 142 women aged 40-74 years from the five areas included in the JPHCNEXT protocol. In November 2012, participants were recruited and asked to complete the first nutrition survey. The second nutrition survey was completed after 1 year. RESULTS: We estimated daily energy as well as 53 nutrient and 29 food group intakes using the FFQ. To assess reproducibility, we calculated Spearman correlation coefficients between both FFQs, which showed mostly intermediate-to-high values. Median (range) correlation coefficients and quartile distribution in the same and adjacent categories for energy-adjusted nutrient intakes were 0.55 (0.42-0.84) and 84.7% (76.5%-98.0%) in men and 0.54 (0.35-0.80) and 84.5% (76.1%-94.4%) in women. The respective values for energy-adjusted food group intakes in men and women were also mostly intermediate to high: 0.54 (0.39-0.79) and 83.7% (75.5%-90.8%) in men and 0.57 (0.40-0.83) and 84.5% (77.5%-93.7%) in women. CONCLUSIONS: The FFQ developed for the JPHC-NEXT study has reasonable reproducibility. Because this FFQ has also been validated in a previous study, it can be considered a useful dietary assessment tool to examine associations between dietary consumption and lifestyle-related diseases., 2019, 28, 2, 362, 370, Scientific journal, True
  • Refereed, Journal of Pain Research, Informa UK Limited, Epidemiological profiles of chronic low back and knee pain in middle-aged and elderly Japanese from the Murakami cohort, Akemi Takahashi; Kaori Kitamura; Yumi Watanabe; Ryosaku Kobayashi; Toshiko Saito; Ribeka Takachi; Keiko Kabasawa; Rieko Oshiki; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kazutoshi Nakamura, Purpose: Epidemiological profiles of chronic low back and knee pain have not been studied extensively. This study aimed to determine the prevalence of and potential risk factors associated with chronic low back and knee pain in middle-aged and elderly Japanese. Methods: This cross-sectional study involved 14,217 community-dwelling individuals aged 40-74 years living in the Murakami area of Japan. A self-administered questionnaire was used to obtain information regarding marital status, education level, occupation, household income, and body size. Participants also reported current chronic pain, if any, by site and degree of severity, using the verbal rating scale of the Short Form 36. Results: The prevalence of moderate-very severe chronic pain was 9.7% in the low back, 6.7% in the knee, 13.9% in either the low back or knee, and 2.6% in both the low back and knee. Multivariate analysis revealed that lower education level, lower income, and manual occupation in men and older age and higher body mass index in women were significantly associated with a higher prevalence of chronic low back pain. In both sexes, older age, lower education level, and higher body mass index were significantly associated with a higher prevalence of knee pain. Regarding sex differences, adjusted ORs of chronic pain of the low back and knee for women were 0.85 (95% CI 0.75-0.97) and 1.27 (95% CI 1.09-1.49), respectively. Conclusion: Nearly 14% of middle-aged and elderly individuals had moderate-very severe chronic pain of the low back or knee, and this pain was associated with many demographic factors, including sex, age, education level, household income, occupation, and body size., Dec. 2018, 11, 3161, 3169, Scientific journal, True
  • Refereed, Environmental Health and Preventive Medicine, Springer Science and Business Media LLC, The Murakami Cohort Study of vitamin D for the prevention of musculoskeletal and other age-related diseases: a study protocol, Kazutoshi Nakamura; Ribeka Takachi; Kaori Kitamura; Toshiko Saito; Ryosaku Kobayashi; Rieko Oshiki; Yumi Watanabe; Keiko Kabasawa; Akemi Takahashi; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki, BACKGROUND: Age-related musculoskeletal diseases are becoming increasingly burdensome in terms of both individual quality of life and medical cost. We intended to establish a large population-based cohort study to determine environmental, lifestyle, and genetic risk factors of musculoskeletal and other age-related diseases, and to clarify the association between vitamin D status and such diseases. METHODS: We targeted 34,802 residents aged 40-74 years living in areas of northern Niigata Prefecture, including Sekikawa Village, Awashimaura Village, and Murakami City (Murakami region). The baseline questionnaire survey, conducted between 2011 and 2013, queried respondents on their lifestyle and environmental factors (predictors), and self-reported outcomes. Plasma 25-hydroxyvitamin D (25[OH]D) concentration, an indicator of vitamin D status, was determined with the Liaison® 25OH Vitamin D Total Assay. The primary outcome of this study was osteoporotic fracture; other outcomes included age-related diseases including knee osteoarthritis, perception of chronic pain, dementia, and long-term care insurance use. Mean ages of men and women were 59.2 (SD = 9.3, N = 6907) and 59.0 (SD = 9.3, N = 7457) years, respectively. From the blood samples provided by 3710 men and 4787 women, mean 25(OH)D concentrations were 56.5 (SD = 18.4) nmol/L (22.6 ng/mL) and 45.4 (SD = 16.5) nmol/L (18.2 ng/mL), respectively. DISCUSSION: Follow-up surveys are planned every 5 years for 15 years, and incident cases of our targeted diseases will be followed at hospitals and clinics in and nearby the cohort area. We anticipate that we will be able to clarify the association between vitamin D status and multiple disease outcomes in a Japanese population., Dec. 2018, 23, 1, 28, 28, Scientific journal, True
  • Refereed, European Journal of Clinical Nutrition, Springer Science and Business Media LLC, Effect of monitoring salt concentration of home-prepared dishes and using low-sodium seasonings on sodium intake reduction, Misako Nakadate; Junko Ishihara; Motoki Iwasaki; Kaori Kitamura; Erika Kato; Junta Tanaka; Kazutoshi Nakamura; Takuma Ishihara; Ayumi Shintani; Ribeka Takachi, BACKGROUND/OBJECTIVES: Objective methods such as the monitoring of salt concentrations in home-prepared dishes may be effective in reducing salt intake. We investigated the effect of monitoring the salt concentration of home-prepared dishes (Monitoring) on salt reduction and change in taste threshold, and the effect of the simultaneous use of low-sodium seasonings (Seasoning) to compare the effect of Monitoring with the conventional method. SUBJECTS/METHODS: We conducted a double-blind randomized controlled study using a 2 × 2 factorial design with two interventions. A total of 50 participants (40-75 years-old) were recruited among residents of Niigata Prefecture, a high sodium-consuming population in Japan, then randomly allocated to four groups. After excluding participants with incomplete urine collection, change in salt intake was evaluated using 24-hour urinary excretion as a surrogate of intake for 43 participants. Change in taste threshold was evaluated in 48 participants after excluding those with incomplete threshold measurement. RESULTS: The Monitoring intervention group showed a significant decrease in sodium intake (-777 mg/24 h), whereas the decrease in the Seasoning intervention group was not significant (-413 mg/24 h). Sodium intake did not statistically differ between the intervention and control groups (-1011 mg/24 h and -283 mg/24 h for Monitoring and Seasoning, respectively). The changes in taste threshold measurement were very small and did not markedly differ between groups. CONCLUSIONS: Monitoring the salt concentration of dishes had a potentially stronger salt-reducing effect than the use of low-sodium seasonings, a conventional method. Confirmation requires additional study with a larger sample size., Oct. 2018, 72, 10, 1413, 1420, Scientific journal, True
  • Refereed, International Journal of Cancer, Wiley, Dietary consumption of antioxidant vitamins and subsequent lung cancer risk: The Japan Public Health Center-based prospective study, Saki Narita; Eiko Saito; Norie Sawada; Taichi Shimazu; Taiki Yamaji; Motoki Iwasaki; Junko Ishihara; Ribeka Takachi; Kenji Shibuya; Manami Inoue; Shoichiro Tsugane, While many epidemiological studies have studied the association between lung cancer risk and fruits and vegetable consumption (the major sources of antioxidant vitamins), only a few have investigated the direct association with antioxidants in consideration of cancer subtypes and smoking status. Here, we examined the association between consumption of antioxidant vitamins and lung cancer risk in one of the largest prospective cohort studies in Japan. We investigated the association of dietary antioxidant vitamins intake, namely retinol, vitamin C, vitamin E, α-carotene, and β-carotene and subsequent incidence of lung cancer among 38,207 men and 41,498 women in the Japan Public Health Center-based prospective study. Cox proportional hazard regression was performed with adjustment for potential confounders and by strata of cancer subtypes and smoking status. Antioxidant and other dietary intakes were assessed using a food frequency questionnaire (FFQ). During 1,233,096 person-years of follow-up between 1995 and 2013, a total of 1,690 lung cancer cases were newly diagnosed. In a multivariate regression model, while higher retinol intake was positively associated with overall lung cancer risk in men (HR 1.26; 95% CI 1.05-1.51; ptrend  = 0.003), the estimates were more evident with small cell carcinoma (HR 1.92; 95% CI 1.13-3.24; ptrend  < 0.001). Null associations were observed for other antioxidant vitamins. Our prospective study suggests that higher consumption of retinol may be associated with an increased risk of lung cancer in men, especially with small cell carcinoma, although confirmation is required., 15 Jun. 2018, 142, 12, 2441, 2460, Scientific journal, True
  • Refereed, Cancer Causes & Control, Springer Science and Business Media LLC, Dietary patterns and prostate cancer risk in Japanese: the Japan Public Health Center-based Prospective Study (JPHC Study), Sangah Shin; Eiko Saito; Norie Sawada; Junko Ishihara; Ribeka Takachi; Akiko Nanri; Taichi Shimazu; Taiki Yamaji; Motoki Iwasaki; Shizuka Sasazuki; Manami Inoue; Shoichiro Tsugane, PURPOSE: The development of prostate cancer may be impacted by environmental factors, including diet. The aim of this study was to evaluate the association between dietary patterns and risk of prostate cancer in a large prospective cohort study among Japanese men. METHODS: A total of 43,469 men who participated in the Japan Public Health Center-based Prospective Study were followed from 1995 to 1998 to the end of 2012, during which 1,156 cases of prostate cancer were newly identified. Dietary intake was assessed using a validated food frequency questionnaire in the 5-year follow-up survey. RESULTS: Three major dietary patterns were derived using exploratory factors analysis: prudent, westernized, and traditional dietary patterns. The westernized dietary pattern was associated with a higher risk of total prostate cancer (HR: 1.22; 95% CI 1.00-1.49; p trend = 0.021), localized cancer (HR: 1.24; 95% CI 0.97-1.57; p trend = 0.045), and advanced cancer (HR: 1.23; 95% CI 0.82-1.84; p trend = 0.233). The prudent dietary pattern was associated with a lower risk of total and localized prostate cancer, with respective multivariable HRs for the highest and lowest quintiles of 0.71 (95% CI 0.50-1.02; p trend = 0.037) and 0.63 (95% CI 0.38-1.03; p trend = 0.048) among subjects detected by subjective symptoms. No association was found between the traditional dietary pattern and prostate cancer risk among our subjects. CONCLUSION: Our results suggest that a western-style diet may lead to a higher risk of prostate cancer in the total population, whereas the prudent diet contributes to a lower risk among subjects detected by subjective symptoms., Jun. 2018, 29, 6, 589, 600, Scientific journal, True
  • Refereed, Clinical Nutrition, Elsevier BV, Dietary patterns and colorectal cancer risk in middle-aged adults: A large population-based prospective cohort study, Sangah Shin; Eiko Saito; Norie Sawada; Junko Ishihara; Ribeka Takachi; Akiko Nanri; Taichi Shimazu; Taiki Yamaji; Motoki Iwasaki; Shizuka Sasazuki; Manami Inoue; Shoichiro Tsugane; S. Tsugane; JPHC Study group., BACKGROUND & AIMS: A finding between dietary pattern and cancer may provide visions beyond the assessment of individual foods or nutrients. We examined the influence of dietary pattern with colorectal cancer (CRC) among a Japanese population. METHODS: A total of 93,062 subjects (43,591 men, 49,471 women) who participated in the Japan Public Health Center-based Prospective Study were followed from 1995-1998 to the end of 2012, during which 2482 cases of CRC (1514 men, 968 women) were newly identified. Dietary data was obtained from a validated food-frequency questionnaire between 1995 and 1998. RESULTS: Three dietary pattern was derived from principal components factor: prudent, westernized, and traditional pattern. After controlled for potential confounders, the prudent pattern showed a decreased association of CRC risk in men (HR for highest quintile vs lowest: 0.85; 95% CI: 0.72-1.00; P trend <0.05), slightly more strongly with distal colon cancer (P trend <0.05); but an increased risk of rectal cancer in women (P trend <0.05). The westernized pattern showed a significant positive linear trend for colon (P trend <0.05) and distal cancer (P trend <0.05) in women. There was no apparent association of traditional Japanese dietary pattern on the overall or any specific sites risk of CRC. CONCLUSIONS: A prudent dietary pattern showed an inverse association with CRC risk in men, and a westernized pattern was related with a higher risk of colon and distal cancer in women., Jun. 2018, 37, 3, 1019, 1026, Scientific journal, True
  • Refereed, European Journal of Clinical Nutrition, Springer Science and Business Media LLC, Dietary intake of antioxidant vitamins and risk of stroke: the Japan Public Health Center–based Prospective Study, S Uesugi; J Ishihara; H Iso; N Sawada; R Takachi; M Inoue; S Tsugane, Oct. 2017, 71, 10, 1179, 1185, Scientific journal
  • Refereed, PLOS ONE, Public Library of Science (PLoS), Weight loss from 20 years of age is associated with cognitive impairment in middle-aged and elderly individuals, Kaori Kitamura; Yumi Watanabe; Kazutoshi Nakamura; Akemi Takahashi; Ribeka Takachi; Rieko Oshiki; Ryosaku Kobayashi; Toshiko Saito; Shoichiro Tsugane; Ayako Sasaki, Oct. 2017, 12, 10, e0185960, e0185960, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Online version of the self-administered food frequency questionnaire for the Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT) protocol: Relative validity, usability, and comparison with a printed questionnaire, Erika Kato; Ribeka Takachi; Junko Ishihara; Yuri Ishii; Shizuka Sasazuki; Norie Sawada; Motoki Iwasaki; Yurie Shinozawa; Jun Umezawa; Junta Tanaka; Yuta Yokoyama; Kaori Kitamura; Kazutoshi Nakamura; Shoichiro Tsugane,

    Background: Online dietary assessment tools offer advantages over printed questionnaires, such as the automatic and direct data storage of answers, and have the potential to become valuable research methods. We developed an online survey system (web-FFQ) for the existing printed FFQ used in the JPHC-NEXT protocol, the platform of a large-scale genetic cohort study. Here, we examined the validity of ranking individuals according to dietary intake using this web-FFQ and its usability compared with the printed questionnaire (print-FFQ) for combined usage.

    Methods: We included 237 men and women aged 40–74 years from five areas specified in the JPHC-NEXT protocol. From 2012 to 2013, participants were asked to provide 12-day weighed food records (12d-WFR) as the reference intake and to respond to the print- and web-FFQs. Spearman's correlation coefficients (CCs) between estimates using the web-FFQ and 12d-WFR were calculated. Cross-classification of intakes was compared with those using the print-FFQ.

    Results: Most participants (83%) answered that completing the web-FFQ was comparable to or easier than completing the printed questionnaire. The median value of CCs across energy and 53 nutrients for men and women was 0.47 (range, 0.10–0.86) and 0.46 (range, 0.16–0.69), respectively. CCs for individual nutrient intakes were closely similar to those based on the print-FFQ, irrespective of response location. Cross-classification by quintile of intake based on two FFQs was reasonably accurate for many nutrients and food groups.

    Conclusion: This online survey system is a reasonably valid measure for ranking individuals by intake for many nutrients, like the printed FFQ. Mixing of two FFQs for exposure assessments in epidemiological studies appears acceptable.

    , Sep. 2017, 27, 9, 435, 446, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Comparison of weighed food record procedures for the reference methods in two validation studies of food frequency questionnaires, Yuri Ishii; Junko Ishihara; Ribeka Takachi; Yurie Shinozawa; Nahomi Imaeda; Chiho Goto; Kenji Wakai; Toshiaki Takahashi; Hiroyasu Iso; Kazutoshi Nakamura; Junta Tanaka; Taichi Shimazu; Taiki Yamaji; Shizuka Sasazuki; Norie Sawada; Motoki Iwasaki; Haruo Mikami; Kiyonori Kuriki; Mariko Naito; Naoko Okamoto; Fumi Kondo; Satoyo Hosono; Naoko Miyagawa; Etsuko Ozaki; Sakurako Katsuura-Kamano; Keizo Ohnaka; Hinako Nanri; Noriko Tsunematsu-Nakahata; Takamasa Kayama; Ayako Kurihara; Shiomi Kojima; Hideo Tanaka; Shoichiro Tsugane, Jul. 2017, 27, 7, 331, 337, Scientific journal
  • Refereed, The Journal of Nutrition, Oxford University Press (OUP), Cruciferous Vegetable Intake Is Inversely Associated with Lung Cancer Risk among Current Nonsmoking Men in the Japan Public Health Center (JPHC) Study, Nagisa Mori; Taichi Shimazu; Shizuka Sasazuki; Miho Nozue; Michihiro Mutoh; Norie Sawada; Motoki Iwasaki; Taiki Yamaji; Manami Inoue; Ribeka Takachi; Ayaka Sunami; Junko Ishihara; Tomotaka Sobue; Shoichiro Tsugane, May 2017, 147, 5, 841, 849, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Fruit and vegetable intake and the risk of overall cancer in Japanese: A pooled analysis of population-based cohort studies, Ribeka Takachi; Manami Inoue; Yumi Sugawara; Ichiro Tsuji; Shoichiro Tsugane; Hidemi Ito; Keitaro Matsuo; Keitaro Tanaka; Akiko Tamakoshi; Tetsuya Mizoue; Kenji Wakai; Chisato Nagata; Shizuka Sasazuki, Apr. 2017, 27, 4, 152, 162, Scientific journal
  • Refereed, PLOS ONE, Public Library of Science (PLoS), Dietary patterns and all-cause, cancer, and cardiovascular disease mortality in Japanese men and women: The Japan public health center-based prospective study, Akiko Nanri; Tetsuya Mizoue; Taichi Shimazu; Junko Ishihara; Ribeka Takachi; Mitsuhiko Noda; Hiroyasu Iso; Shizuka Sasazuki; Norie Sawada; Shoichiro Tsugane, Apr. 2017, 12, 4, e0174848, e0174848, Scientific journal
  • Refereed, 家政学研究 = Research journal of living science, 奈良女子大学家政学会, Development and pilot study of a web-based computerized 24-hour dietary recall system : Automated web-based assessment system using recipe-data for Japanese : AWARDJP, 大内 詩野; 髙地 リベカ; 小田 瑞希; 林 えりこ; 山岸 万里菜; 斉藤 裕美; 中舘 美佐子; 石原 淳子, Mar. 2017, 63, 2, 54, 64
  • Refereed, British Journal of Nutrition, Cambridge University Press (CUP), Dietary pattern and breast cancer risk in Japanese women: the Japan Public Health Center-based Prospective Study (JPHC Study), Sangah Shin; Eiko Saito; Manami Inoue; Norie Sawada; Junko Ishihara; Ribeka Takachi; Akiko Nanri; Taichi Shimazu; Taiki Yamaji; Motoki Iwasaki; Shizuka Sasazuki; Shoichiro Tsugane, AbstractEvidence that diet is associated with breast cancer risk is inconsistent. Most of the studies have focused on risks associated with specific foods and nutrients, rather than overall diet. In this study, we aimed to evaluate the association between dietary patterns and breast cancer risk in Japanese women. A total of 49 552 Japanese women were followed-up from 1995 to 1998 (5-year follow-up survey) until the end of 2012 for an average of 14·6 years. During 725 534 person-years of follow-up, 718 cases of breast cancer were identified. We identified three dietary patterns (prudent, westernised and traditional Japanese). The westernised dietary pattern was associated with a 32 % increase in breast cancer risk (hazard ratios (HR) 1·32; 95 % CI 1·03, 1·70; Ptrend=0·04). In particular, subjects with extreme intake of the westernised diet (quintile (Q) Q5_5th) had an 83 % increase in risk of breast cancer in contrast to those in the lowest Q1 (HR 1·83; 95 % CI 1·25, 2·68; Ptrend=0·01). In analyses stratified by menopausal status, postmenopausal subjects in the highest quintile of the westernised dietary pattern had a 29 % increased risk of breast cancer (HR 1·29; 95 % CI 0·99, 1·76; Ptrend=0·04). With regard to hormone receptor status, the westernised dietary pattern was associated with an increased risk of oestrogen receptor-positive/progesterone receptor-positivetumours (HR 2·49; 95 % CI 1·40, 4·43; Ptrend<0·01). The other dietary patterns were not associated with the risk of breast cancer in Japanese women. A westernised dietary pattern is associated with an increased risk of breast cancer in Japanese women., May 2016, 115, 10, 1769, 1779, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Validity of a Self-Administered Food-Frequency Questionnaire for Assessing Amino Acid Intake in Japan: Comparison With Intake From 4-Day Weighed Dietary Records and Plasma Levels, Motoki Iwasaki; Junko Ishihara; Ribeka Takachi; Hidemi Todoriki; Hiroshi Yamamoto; Hiroshi Miyano; Taiki Yamaji; Shoichiro Tsugane, 2016, 26, 1, 36, 44, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Validity of Short and Long Self-Administered Food Frequency Questionnaires in Ranking Dietary Intake in Middle-Aged and Elderly Japanese in the Japan Public Health Center-Based Prospective Study for the Next Generation (JPHC-NEXT) Protocol Area, Yuta Yokoyama; Ribeka Takachi; Junko Ishihara; Yuri Ishii; Shizuka Sasazuki; Norie Sawada; Yurie Shinozawa; Junta Tanaka; Erika Kato; Kaori Kitamura; Kazutoshi Nakamura; Shoichiro Tsugane, Background: Longitudinal epidemiological studies require both the periodic update of intake information via repeated dietary survey and the minimization of subject burden in responding to questionnaires. We developed a 66-item Food Frequency Questionnaire (short-FFQ) for the Japan Public Health Center-based prospective Study for the Next Generation (JPHC-NEXT) follow-up survey using major foods from the FFQ developed for the original JPHC Study. For the JPHC-NEXT baseline survey, we used a larger 172-item FFQ (long-FFQ), which was also derived from the JPHC-FFQ. We compared the validity of ranking individuals by levels of dietary consumption by these FFQs among residents of selected JPHC-NEXT study areas.
    Methods: From 2012 to 2013, 240 men and women aged 40–74 years from five areas in the JPHC-NEXT protocol were asked to respond to the long-FFQ and provide 12-day weighed food records (WFR) as reference; 228 also completed the short-FFQ. Spearman's correlation coefficients (CCs) between estimates from the FFQs and WFR were calculated and corrected for intra-individual variation of the WFR.
    Results: Median CC values for energy and 53 nutrients for the short-FFQ for men and women were 0.46 and 0.44, respectively. Respective values for the long-FFQ were 0.50 and 0.43. Compared with the long-FFQ, cross-classification into exact plus adjacent quintiles with the short-FFQ ranged from 68% to 91% in men and 58% to 85% in women.
    Conclusions: Similar to the long-FFQ, the short-FFQ provided reasonably valid measures for ranking middle-aged and elderly Japanese for many nutrients and food groups. The short-FFQ can be used in follow-up surveys in prospective cohort studies aimed at updating diet rank information., 2016, 26, 8, 420, 432, Scientific journal
  • Refereed, Bone, Elsevier BV, Impact of demographic, environmental, and lifestyle factors on vitamin D sufficiency in 9084 Japanese adults, K. Nakamura; K. Kitamura; R. Takachi; T. Saito; R. Kobayashi; R. Oshiki; Y. Watanabe; S. Tsugane; A. Sasaki; O. Yamazaki, May 2015, 74, 10, 17, Scientific journal
  • Refereed, European Journal of Cancer Prevention, Ovid Technologies (Wolters Kluwer Health), Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA, Motoki Iwasaki; Adrian A. Franke; Gerson S. Hamada; Nelson T. Miyajima; Sangita Sharma; Junko Ishihara; Ribeka Takachi; Shoichiro Tsugane; Loïc Le Marchand, Mar. 2015, 24, 2, 155, 161, Scientific journal
  • Refereed, Cancer Epidemiology Biomarkers & Prevention, American Association for Cancer Research (AACR), Dietary Heterocyclic Amine Intake, NAT2 Genetic Polymorphism, and Colorectal Adenoma Risk: The Colorectal Adenoma Study in Tokyo, Sanjeev Budhathoki; Motoki Iwasaki; Taiki Yamaji; Shizuka Sasazuki; Ribeka Takachi; Hiromi Sakamoto; Teruhiko Yoshida; Shoichiro Tsugane, Mar. 2015, 24, 3, 613, 620, Scientific journal
  • Refereed, Cancer Causes & Control, Springer Science and Business Media LLC, Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines, Motoki Iwasaki; Tomomi Mukai; Ribeka Takachi; Junko Ishihara; Yukari Totsuka; Shoichiro Tsugane, Aug. 2014, 25, 8, 1015, 1028, Scientific journal
  • Refereed, Journal of the Academy of Nutrition and Dietetics, Elsevier BV, Self-Reported Taste Preference Can Be a Proxy for Daily Sodium Intake in Middle-Aged Japanese Adults, Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Yuri Ishii; Shoichiro Tsugane, May 2014, 114, 5, 781, 787, Scientific journal
  • Refereed, International Journal of Hygiene and Environmental Health, Elsevier BV, Dietary cadmium intake and breast cancer risk in Japanese women: A case–control study, Hiroaki Itoh; Motoki Iwasaki; Norie Sawada; Ribeka Takachi; Yoshio Kasuga; Shiro Yokoyama; Hiroshi Onuma; Hideki Nishimura; Ritsu Kusama; Kazuhito Yokoyama; Shoichiro Tsugane, Jan. 2014, 217, 1, 70, 77, Scientific journal
  • Refereed, Cancer Causes & Control, Springer Science and Business Media LLC, Dietary arsenic intake and subsequent risk of cancer: the Japan Public Health Center-based (JPHC) Prospective Study, Norie Sawada; Motoki Iwasaki; Manami Inoue; Ribeka Takachi; Shizuka Sasazuki; Taiki Yamaji; Taichi Shimazu; Shoichiro Tsugane, Jul. 2013, 24, 7, 1403, 1415, Scientific journal
  • Refereed, European Journal of Clinical Nutrition, Springer Science and Business Media LLC, Dietary patterns and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study, A Nanri; T Shimazu; R Takachi; J Ishihara; T Mizoue; M Noda; M Inoue; S Tsugane, Jan. 2013, 67, 1, 18, 24, Scientific journal
  • Refereed, 新潟医学会雑誌, 新潟医学会, Secular Trends of Cerebrovascular Disease, Salt Intake, and The Percentage Contribution to Total Salt Intake by Food Groups in Japan, Sakaguchi Yuta; Gibo Tomoki; Takachi Ribeka, わが国における死因別死亡率では1980年代まで脳血管疾患が第一位を占め, 現在も欧米と比べ死亡率が高い. また, 部位別の悪性新生物年齢調整死亡率では胃がんが欧米と比して著名に高い. 食塩の過剰摂取はこれらの疾患に共通するリスク要因である. 日本人の食塩摂取量は年々減少していると言われているものの, 今なお一人1日当たり平均10.5g摂取しており, 推奨値6g/日とは大きく隔たりがある. 本研究の目的は, 脳血管疾患と食塩摂取量の推移により両者の動向と関連性を観察すること, 及び食塩摂取量の性・年齢階級別推移及び食塩摂取量に寄与する食品の推移を記述することにより食塩摂取量低減のターゲットを明らかにすることである. 記述疫学的研究デザインにより, 政府統計による脳血管疾患年齢調整死亡率の年次推移及び厚生労働省国民健康・栄養調査結果による年次推移を観察した. その結果, 脳血管疾患の年齢調整死亡率は男女ともに最近の40年間減少し続けていた..食塩摂取量も長期的には減少傾向にあり,各年齢階級においても同様に推移していた. エネルギー1,000keal当たりの調整食塩摂取量は一定で稚移し,調味料の食塩摂取量への寄与は1980年から増加傾向にあり,2001年以降約70%とほぼ一定で推移していることが明らかになった.今後さらなる食塩の摂取量の低減のためには調味料によりもたらされる食塩,及び中高年世代の食塩摂取量の低減が重要なタ-ゲットであることが示唆された., 2013, 127, 1, 48, 54
  • Refereed, 新潟医学会雑誌, 日本人における虚血性心疾患死亡率、脂質摂取量及び食品群別寄与率の推移, 宜保智樹; 坂口裕太; 高地リベカ, 2013, 127, 103, 7
  • Refereed, Journal of Bone and Mineral Research, Wiley, Effect of low-dose calcium supplements on bone loss in perimenopausal and postmenopausal Asian women: A randomized controlled trial, Kazutoshi Nakamura; Toshiko Saito; Ryosaku Kobayashi; Rieko Oshiki; Kaori Kitamura; Mari Oyama; Sachiko Narisawa; Mitsue Nashimoto; Shunsuke Takahashi; Ribeka Takachi, Nov. 2012, 27, 11, 2264, 2270, Scientific journal
  • Refereed, The American Journal of Clinical Nutrition, Oxford University Press (OUP), Zinc and heme iron intakes and risk of colorectal cancer: a population-based prospective cohort study in Japan, Azusa Hara; Shizuka Sasazuki; Manami Inoue; Motoki Iwasaki; Taichi Shimazu; Norie Sawada; Taiki Yamaji; Ribeka Takachi; Shoichiro Tsugane, 01 Oct. 2012, 96, 4, 864, 873, Scientific journal
  • Refereed, Nihon Koshu Eisei Zasshi(JAPANESE JOURNAL OF PUBLIC HEALTH), Japanese Society of Public Health, Applicability of the Dietary Record by Cooked Dishes method for estimating dietary intake of populations in the areas other than where the database was developed, KITO Kumiko; ISHIHARA Junko; KIMIRA Mitsuru; TAKACHI Ribeka; HOSOI Satoko; ISHII Yuri; IWASAKI Motoki, Objectives The Dietary Record by Cooked Dishes (DRcd) method, which enables simple assessment of food and nutrient intake, is unique because it uses a nutrient database of cooked dishes. Although this method has been validated among the rural Japanese populations for which the database was developed, the applicability of the DRcd for other populations is unclear. In this study, we have examined the applicability of DRcd among an urban population.
    Methods Subjects were selected from among patients who underwent cancer screening between 2004 and 2006 at the Research Center for Cancer Prevention and Screening, National Cancer Center, Japan. Subjects aged 40–69 years, who lived in Tokyo and the surrounding suburbs, were stratified into groups by sex and age. A total of 144 men and women agreed to participate in the study after random selection. Subjects were instructed to keep 4-day dietary records (4d-DR) of all consumed foods and beverages, including dish names, and all dishes were then coded using DRcd codes on the basis their names. The intake of 17 food groups and 40 nutrients was estimated using the dish-based nutrient composition table of the DRcd. Simultaneously, 4d-DR were used to calculate dietary intake independently, which served as a reference. We examined the applicability of the DRcd method using percentage difference and Pearson's correlation coefficients for intakes estimated using 4d-DR and the DRcd. Moreover, the results were compared to those of a previous study.
    Results A total of 88% of the recorded dishes matched the dish codes of the DRcd database by name. Pearson's correlation coefficient scores of 0.6 or higher were observed for 12 and 10 food groups, and for 34 and 27 nutrients in men and women, respectively. Notably, the intake of majority of the nutrients tended to be underestimated, a difference that was more pronounced in men. In comparison with a previous study, the percentage differences and Pearson's correlation coefficient scores for intake tended to be lower in our study.
    Conclusion As the correlation coefficients (0.6) were high for a majority of food groups and nutrients estimated by DRcd, the DRcd method may be applicable for urban populations. However, regional intake data may be necessary for the estimation of absolute value for the intake of some nutrients., 15 Sep. 2012, 59, 9, 700, 711
  • Refereed, Gastroenterology, Elsevier BV, Consumption of n-3 Fatty Acids and Fish Reduces Risk of Hepatocellular Carcinoma, Norie Sawada; Manami Inoue; Motoki Iwasaki; Shizuka Sasazuki; Taichi Shimazu; Taiki Yamaji; Ribeka Takachi; Yasuhito Tanaka; Masashi Mizokami; Shoichiro Tsugane, Jun. 2012, 142, 7, 1468, 1475, Scientific journal
  • Refereed, Epidemiology, Ovid Technologies (Wolters Kluwer Health), Long-term Dietary Cadmium Intake and Cancer Incidence, Norie Sawada; Motoki Iwasaki; Manami Inoue; Ribeka Takachi; Shizuka Sasazuki; Taiki Yamaji; Taichi Shimazu; Yoko Endo; Shoichiro Tsugane, May 2012, 23, 3, 368, 376, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Reproducibility and Validity of Dietary Patterns Assessed by a Food Frequency Questionnaire Used in the 5-Year Follow-Up Survey of the Japan Public Health Center-Based Prospective Study, Akiko Nanri; Taichi Shimazu; Junko Ishihara; Ribeka Takachi; Tetsuya Mizoue; Manami Inoue; Shoichiro Tsugane, Background: Analysis of dietary pattern is increasingly popular in nutritional epidemiology. However, few studies have examined the validity and reproducibility of dietary patterns. We assessed the reproducibility and validity of dietary patterns identified by a food frequency questionnaire (FFQ) used in the 5-year follow-up survey of the Japan Public Health Center-Based Prospective Study (JPHC Study).
    Methods: The participants were a subsample (244 men and 254 women) from the JPHC Study. Principal component analysis was used to identify dietary patterns from 28- or 14-day dietary records and 2 FFQs. To assess reproducibility and validity, we calculated Spearman correlation coefficients between dietary pattern scores derived from FFQs separated by a 1-year interval, and between dietary pattern scores derived from dietary records and those derived from a FFQ completed after the dietary records, respectively.
    Results: We identified 3 Japanese dietary patterns from the dietary records and 2 FFQs: prudent, westernized, and traditional. Regarding reproducibility, Spearman correlation coefficients between the 2 FFQs ranged from 0.55 for the westernized Japanese pattern in men and the prudent Japanese pattern in women to 0.77 for the traditional Japanese pattern in men. Regarding validity, the corresponding values between dietary records and the FFQ ranged from 0.32 for the westernized Japanese pattern in men to 0.63 for the traditional Japanese pattern in women.
    Conclusions: Acceptable reproducibility and validity was shown by the 3 dietary patterns identified by principal component analysis based on the FFQ used in the 5-year follow-up survey of the JPHC Study., 2012, 22, 3, 205, 215, Scientific journal
  • Refereed, International Journal of Cancer, Wiley, Intake of n-3 and n-6 polyunsaturated fatty acids and development of colorectal cancer by subsite: Japan Public Health Center-based prospective study, Shizuka Sasazuki; Manami Inoue; Motoki Iwasaki; Norie Sawada; Taichi Shimazu; Taiki Yamaji; Ribeka Takachi; Shoichiro Tsugane, Oct. 2011, 129, 7, 1718, 1729, Scientific journal
  • Refereed, Asia Pac J Clin Nutr, H E C PRESS, HEALTHY EATING CLUB PTY LTD, Red meat intake may increase the risk of colon cancer in Japanese, a population with relatively low red meat consumption, Ribeka Takachi; Yoshitaka Tsubono; Keisuke Baba; Manami Inoue; Shizuka Sasazuki; Motoki Iwasaki; Shoichiro Tsugane, Asian populations have changed from traditional to Westernized diets, with increased red meat intake. They are suggested to be particularly susceptible to the adverse effects of red meat on the development of colorectal cancers, however, few prospective studies of this putative link have been conducted. We examined associations between the consumption of red and processed meat and the risk of subsite-specific colorectal cancer by gender in a large Japanese cohort. During 1995-1998, a validated food frequency questionnaire was administered to 80,658 men and women aged 45-74 years. During 758,116 person-years of follow-up until the end of 2006, 1,145 cases of colorectal cancer were identified. Higher consumption of red meat was significantly associated with a higher risk of colon cancer among women [multivariate hazard ratios (95%CIs) for the highest versus lowest quintiles (HR): 1.48 (1.01, 2.17; trend p=0.03)], as was higher consumption of total meat among men [HR=1.44 (1.06, 1.98; trend p=0.07)]. By site, these positive associations were found for the risk of proximal colon cancer among women and for distal colon cancer among men. No association was found between the consumption of processed meat and risk of either colon or rectal cancer. In conclusion, red meat intake may modestly increase the risk of colon cancer in middle-aged Japanese, although the highest quintile of red meat consumption could be considered moderate by Western standards., 2011, 20, 4, 603, 612, Scientific journal
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Validity of a Self-Administered Food Frequency Questionnaire for Middle-Aged Urban Cancer Screenees: Comparison With 4-Day Weighed Dietary Records, Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Satoko Hosoi; Yuri Ishii; Shizuka Sasazuki; Norie Sawada; Taiki Yamaji; Taichi Shimazu; Manami Inoue; Shoichiro Tsugane, Background: The validity of estimates of dietary intake calculated using a food frequency questionnaire (FFQ) depends on the specific population. The 138-item FFQ used in the 5-year follow-up survey for the Japan Public Health Center-based Prospective Study was initially developed for and validated in rural residents. However, the validity of estimates based on this FFQ for urban residents, whose diet and lifestyle differ from those of rural residents, has not been clarified. We examined the validity of ranking individuals according to level of dietary consumption, as estimated by this FFQ, among an urban population in Japan.
    Methods: Among 896 candidates randomly selected from examinees of cancer screening provided by the National Cancer Center, Japan, 144 participated in the study. In 2007–2008, at an average 2.7 years after cancer screening, participants were asked to respond to the questionnaire and to provide 4-day weighed diet records (4d-DRs) for use as the reference intake. Spearman correlation coefficients (CCs) between the FFQ and 4d-DR estimates were calculated, after correction for intraindividual variation of 4d-DRs.
    Results: The median (range) deattenuated CC for men and women was 0.57 (0.23 to 0.89) and 0.47 (0.08 to 0.94), respectively, across 45 nutrients and 0.51 (0.10 to 0.98) and 0.51 (−0.36 to 0.88) for 43 food groups.
    Conclusions: Although the FFQ was developed for a rural population, it provided reasonably valid measures of consumption for many nutrients and food groups in middle-aged screenees living in urban areas in Japan., 2011, 21, 6, 447, 458, Scientific journal
  • Refereed, Gastric Cancer, Springer Science and Business Media LLC, Socioeconomic status and gastric cancer survival in Japan, Aya Kuwahara; Ribeka Takachi; Yoshitaka Tsubono; Shizuka Sasazuki; Manami Inoue; Shoichiro Tsugane, Nov. 2010, 13, 4, 222, 230, Scientific journal
  • Refereed, AMERICAN JOURNAL OF CLINICAL NUTRITION, AMER SOC CLINICAL NUTRITION, Sodium intake adjustment in the evaluation of the association between salted foods and risk of cancer and cardiovascular disease Reply, Ribeka Takachi; Yoshitaka Tsubono; Manami Inoue; Shoichiro Tsugane, Sep. 2010, 92, 3, 668, 669
  • Refereed, The American Journal of Clinical Nutrition, Oxford University Press (OUP), Confounders in Asian studies Reply, Ribeka Takachi; Yoshitaka Tsubono; Manami Inoue; Shoichiro Tsugane, Jun. 2010, 91, 6, 1805, 1806, Scientific journal
  • Refereed, Journal of Nutrition, Oxford University Press (OUP), High Dietary Intake of Magnesium May Decrease Risk of Colorectal Cancer in Japanese Men, E. Ma; S. Sasazuki; M. Inoue; M. Iwasaki; N. Sawada; R. Takachi; S. Tsugane, Apr. 2010, 140, 4, 779, 785, Scientific journal
  • Refereed, Journal of Food Composition and Analysis, Elsevier BV, Heterocyclic amines content of meat and fish cooked by Brazilian methods, Motoki Iwasaki; Hiroyuki Kataoka; Junko Ishihara; Ribeka Takachi; Gerson Shigeaki Hamada; Sangita Sharma; Loïc Le Marchand; Shoichiro Tsugane, Feb. 2010, 23, 1, 61, 69, Scientific journal
  • Refereed, The American Journal of Clinical Nutrition, Oxford University Press (OUP), Consumption of sodium and salted foods in relation to cancer and cardiovascular disease: the Japan Public Health Center–based Prospective Study, Ribeka Takachi; Manami Inoue; Taichi Shimazu; Shizuka Sasazuki; Junko Ishihara; Norie Sawada; Taiki Yamaji; Motoki Iwasaki; Hiroyasu Iso; Yoshitaka Tsubono; Shoichiro Tsugane, Feb. 2010, 91, 2, 456, 464, Scientific journal
  • Refereed, Nutrition and Cancer, Informa UK Limited, Fruits and Vegetables in Relation to Prostate Cancer in Japanese Men: The Japan Public Health Center-Based Prospective Study, Ribeka Takachi; Manami Inoue; Norie Sawada; Motoki Iwasaki; Shizuka Sasazuki; Junko Ishihara; Yoshitaka Tsubono; Shoichiro Tsugane; for the Japan Public Health Center-, Dec. 2009, 62, 1, 30, 39, Scientific journal
  • Refereed, The Japanese Journal of Nutrition and Dietetics, The Japanese Society of Nutrition and Dietetics, Application of Digital Photographic Images of Meals to Assess Dietary Intake in Epidemiological Studies, ISHIHARA Junko; TAKACHI Ribeka; HOSOI Satoko; IWASAKI Motoki, We compiled 4-day dietary records with digital photographic images of meals to investigate the variation of frequently consumed foods which could enable the development of a dish-based database for dietary assessment in epidemiological studies. We also evaluated the validity of using a digital photographic image as a tool to assess the dietary intake of a food group. Participants in the study were 144 men and women living in urban areas of Japan who were asked to take pictures with a digital camera of all foods and beverages they consumed during 4 consecutive days. Simultaneous dietary records were used as the reference. The dietary intake was independently calculated from the two methods. We found that the variation in intake was high for such seasoning as salt which indicated that the degree of measurement error may be high when a representative portion size for such seasoning was used in a dish-based database. The estimated intake level by two methods was similar for green-yellow vegetables, fruit, fish, meat, eggs, milk and other dairy products, whereas the over/under-estimation for other food groups was too great to be used for accurate assessment. In contrast, the validity for ranking individuals by the estimated multiple-day intake was relatively high, with the exception of beverages, seasonings and spices., 01 Oct. 2009, 67, 5, 252, 259
  • Refereed, 日本給食経営管理学会誌, 日本給食経営管理学会, Study on menu-related factors affecting the planning of providing amounts of fatty acids in food service among college women, 上杉宰世; 彦坂令子; 大川正美; 高地リベカ; 君羅満, Sep. 2009, 3, 2, 13, 24
  • 東北大学博士論文, A population- based prospective study of fruit and vegetable intake, and the risk of total cancers, prostate cancer, and cardiovascular disease, Ribeka Takachi, Sep. 2009
  • Refereed, The European Journal of Public Health, Oxford University Press (OUP), Education in relation to incidence of and mortality from cancer and cardiovascular disease in Japan, S. Ito; R. Takachi; M. Inoue; N. Kurahashi; M. Iwasaki; S. Sasazuki; H. Iso; Y. Tsubono; S. Tsugane, Oct. 2008, 18, 5, 466, 472, Scientific journal
  • Refereed, American Journal of Epidemiology, Oxford University Press (OUP), Fruit and Vegetable Intake and Risk of Total Cancer and Cardiovascular Disease: Japan Public Health Center-based Prospective Study, R. Takachi; M. Inoue; J. Ishihara; N. Kurahashi; M. Iwasaki; S. Sasazuki; H. Iso; Y. Tsubono; S. Tsugane, Nov. 2007, 167, 1, 59, 70, Scientific journal
  • Refereed, The Japanese journal of nutrition and dietetics, 日本栄養改善学会, Validity of Smaller Sample Sizes for the Dish-based Component Table to Use with the Self-reported "Dietary Record by Cooked Dishes", TAKACHI Ribeka; KUDO Yoko; WATANABE Shaw; KIMIRA Mitsuru, Jun. 2006, 64, 2, 97, 105
  • Refereed, 健康・体力・栄養, 尿中ナトリウム、カリウム、リン排泄量による自記式簡易食事調査法「料理単位法」の検討., 工藤陽子; 高地リベカ; 君羅満, Mar. 2005, 10, 2, 108, 17
  • 東京農業大学修士論文, 若年及び高齢女性の脂肪酸摂取と血小板凝集能に関する研究, 高地リベカ, Mar. 2005
  • Refereed, 健康・体力・栄養, 料理単位による食事調査., 君羅満; 高地リベカ; 工藤陽子; 羽場亮太; 上杉宰世; 伊澤正利; 高橋東生; 飯樋洋二; 渡邊昌, Dec. 2004, 10, 1, 3, 13
  • Refereed, Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), The Japanese Society for Hygiene, Associations between Dietary Intake and Urinary Excretion of Sodium, Potassium, Phosphorus, Magnesium, and Calcium, KIMIRA Mitsuru; KUDO Yoko; TAKACHI Ribeka; HABA Ryota; WATANABE Shaw, Objectives and Methods: The associations between dietary intake and urinary excretion of sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), and phosphorus (P), and the major dietary sources derived from the urinary minerals were studied in a nutritional survey of 219 Japanese females aged 27-84 years, who completed anthropometric measurements, a one-day dietary record, and a 24hr urine collection.
    Results: The minerals excreted in the urine were significantly and positively correlated with each other, in which Na excretion was correlated with K and Ca excretion (r=0.490 and r=0.482, respectively, p<0.01) and Ca excretion was correlated with Mg excretion (r=0.526, p<0.01). The ratios of urinary exertion to dietary intake of Na, K, Ca, Mg, and P were 81.5%, 62.7%, 24.5%, 21.7%, and 56.1%, respectively. The dietary intake and the urinary excretion of the minerals expressed per body weight (kg) were significantly and positively correlated (Na, r=0.267; K, r=0.460; Ca, r=0.181; Mg, r=0.245; P, r=0.351, p<0.01). Further examinations using chief component analysis for food intake showed several significant positive correlations, including between Na intake and the intake of vegetables, noodles, and seasonings (r=0.332-0.381, p<0.01); between K, Mg and P intake and the intake of vegetables, fruits, and potatoes (r=0.332-0.533, p<0.01); and between Ca intake and the intake of bread and dairy foods (r=0.428, p<0.01). In addition, significant positive associations were found between Na excretion and the intake of confectionaries, nuts, and seeds (r=0.223, p<0.01). Weak correlations were also found between K excretion and the intake of vegetables (r=0.296, p<0.01); between Ca and P excretion and the intake of meat, oil, and fats (r=0.135, P<0.05; r=0.193, P<0.01, respectively), and between Mg excretion and the intake of bread and dairy foods (r=0.137, P<0.05).
    Conclusions: Findings from this study indicate that, while urinary excretion of Ca and Mg is unlikely to be a reliable biochemical marker of dietary intake, the levels of urinary excretion of Na, K, and P can be reflective of the intake of salt, vegetables, and meats, respectively. The urinary excretion of the minerals, particularly Na, K, and Ca, may be highly linked to salt intake in Japanese females., Jan. 2004, 59, 1, 23, 30
  • Refereed, BioFactors, Wiley, The effect of dietary and plasma fatty acids on platelet aggregation in senior generation of Japanese women, Ribeka Takachi; Mitsuru Kimira; Sayo Uesugi; Yoko Kudo; Kazuyuki Ouchi; Shaw Watanabe, 2004, 22, 1-4, 205, 210, Scientific journal
  • Refereed, British Journal of Nutrition, Cambridge University Press (CUP), Non-alcoholic beverages intake and risk of CVD among Japanese men and women: the Japan Public Health Center study, Renzhe Cui; Hiroyasu Iso; Ehab Salah Eshak; Koutatsu Maruyama; Junko Ishihara; Ribeka Takachi; Norie Sawada; Shoichiro Tsugane, Abstract The association between the intake of non-alcoholic beverages and CVD in Asians is uncertain. The intake of non-alcoholic beverages was estimated in 77 407 participants of the Japan Public Health Centre-based cohort study aged 45–74 years. The Cox regression calculated the hazard ratios (HR) and 95 % CI for incident CVD according to sex-specific quintiles of intake of non-alcoholic beverages. A total of 4578 incident CVD (3751 strokes and 827 CHD) were diagnosed during a 13·6-year median follow-up. The risks of stroke and total CVD were lower for the highest v. lowest intake quintiles of non-alcoholic beverages in men and women: the multivariable HRs (95 % CIs) were 0·82 (0·71, 0·93, Ptrend = 0·005) and 0·86 (0·76, 0·97, Ptrend = 0·02), respectively, in men and were 0·73 (0·63, 0·86, Ptrend = 0·003) and 0·75 (0·65, 0·87, Ptrend = 0·005), respectively, in women. The reduced risk was evident for both ischaemic and haemorrhagic strokes and was mainly attributable to green tea consumption. The intake of non-alcoholic beverages from coffee and other beverages was not associated with the risk of CVD in both men and women. Also, there was no association between the intake of non-alcoholic beverages and the risk of CHD in either sex. In conclusion, the risks of stroke and total CVD were lower with a higher intake of non-alcoholic beverages in Japanese men and women., 21 Jul. 2021, 1, 8, Scientific journal
  • Refereed, European Journal of Clinical Nutrition, Springer Science and Business Media LLC, Validity of dietary isothiocyanate intake estimates from a food frequency questionnaire using 24 h urinary isothiocyanate excretion as an objective biomarker: the JPHC-NEXT protocol area, Nagisa Mori; Norie Sawada; Junpei Yamamoto; Junko Ishihara; Taichi Shimazu; Ribeka Takachi; Utako Murai; Kazutoshi Nakamura; Junta Tanaka; Taiki Yamaji; Motoki Iwasaki; Hiroyasu Iso; Masuko Kobori; Shoichiro Tsugane, BACKGROUND/OBJECTIVES: Isothiocyanate (ITC) is formed via the hydrolysis of glucosinolates by myrosinase, found in cruciferous vegetables. Although myrosinase is inactivated by the cooking process, no studies have incorporated the effect of cooking into the estimation of dietary ITC intake or evaluated the validity. We evaluated the validity of dietary ITC intake estimated from a food frequency questionnaire (FFQ), and urinary ITC levels using 24 h urine samples or a WFR (weighed food record), and evaluated the reproducibility of dietary ITC in two FFQs administered at an interval of 1-year. SUBJECTS/METHODS: The JPHC-NEXT Protocol Area included a total of 255 middle-aged participants across Japan. We calculated dietary ITC intake from WFR and two FFQs by assuming that cooked cruciferous vegetables contain zero ITC. Urinary ITC excretion was measured at two points during summer and winter. The validity and reproducibility of dietary ITC intake estimated by FFQ were assessed using Spearman's correlation coefficients. RESULTS: Although we observed a moderate correlation between dietary ITC intake derived from a 12-day WFR and urinary ITC excretion, notwithstanding the cooking process, the correlation between dietary ITC intake estimated by FFQ and mean urinary ITC excretion was low. However, the correlation was improved when we compared urinary ITC excretion and a 3-day WFR or FFQ collected during winter. Our FFQ showed good reproducibility. CONCLUSION: Although seasonality is a critical factor, dietary ITC intake estimated using an FFQ showed moderate validity and reproducibility and can be used in future epidemiological studies., Mar. 2022, 76, 3, 462, 468, Scientific journal, True
  • Refereed, European Journal of Nutrition, Springer Science and Business Media LLC, Dietary glycemic index, glycemic load and mortality: Japan Public Health Center-based prospective study, Hsi-Lan Huang; Sarah Krull Abe; Norie Sawada; Ribeka Takachi; Junko Ishihara; Motoki Iwasaki; Taiki Yamaji; Hiroyasu Iso; Tetsuya Mizoue; Mitsuhiko Noda; Masahiro Hashizume; Manami Inoue; Shoichiro Tsugane, PURPOSE: Long-term associations of dietary glycemic index (GI) and glycemic load (GL) with mortality outcomes remain unclear. METHODS: The present analysis included 72,783 participants of the Japan Public Health Center-based Prospective Study. Participants who responded to the 5-year follow-up questionnaire in 1995-1999 were followed-up until December 2015. We estimated the risk of total and cause-specific mortality associated with GI and GL using Cox proportional hazards regression models. RESULTS: During 1,244,553 person years of follow-up, 7535 men and 4913 women died. GI was positively associated with all-cause mortality. As compared with the lowest quartile, the multivariable HR for those who had the highest quartile of GI was 1.14 (95% CI 1.08-1.20). The HRs for death comparing the highest with the lowest quartile were 1.28 (95% CI 1.14-1.42) for circulatory system diseases, 1.33 (95% CI 1.14-1.55) for heart disease, 1.32 (95% CI 1.11-1.57) for cerebrovascular disease, and 1.45 (95% CI 1.18-1.78) for respiratory diseases. GI was not associated with mortality risks of cancer and digestive diseases. GL showed a null association with all-cause mortality (highest vs lowest quartile; HR 1.04; 95% CI 0.96-1.12). However, among those who had the highest quartile of GL, the HRs for death from circulatory system diseases was 1.24 (95% CI 1.05-1.46), cerebrovascular disease was 1.34 (95% CI 1.03-1.74), and respiratory diseases was 1.35 (95% CI 1.00-1.82), as compared with the lowest quartile. CONCLUSION: In this large prospective cohort study, dietary GI and GL were associated with mortality risks., Dec. 2021, 60, 8, 4607, 4620, Scientific journal, True
  • Journal of nutritional science, Validity of a food frequency questionnaire for the estimation of total polyphenol intake estimates and its major food sources in the Japanese population: the JPHC FFQ Validation Study., Nagisa Mori; Norie Sawada; Junko Ishihara; Ayaka Kotemori; Ribeka Takachi; Utako Murai; Masuko Kobori; Shoichiro Tsugane, We examine the validity and reproducibility of a food frequency questionnaire (FFQ) in a subsample of participants in the Japan Public Health Center-based Prospective Cohort Study using a database of polyphenol-containing foods commonly consumed in the Japanese population. Participants of the validation study were recruited from two different cohorts. In Cohort I, 215 participants completed a 28-d dietary record (DR) and the FFQ, and in Cohort II, 350 participants completed DRs and the FFQ. The total polyphenol intake estimated from the 28-d DR and FFQ were log-transformed and adjusted for energy intake by the residual method. Spearman correlation coefficients (CCs) between estimates from the FFQ and 28-d DR as well as two FFQs administered at a 1-year interval were computed. Median intakes of dietary polyphenols calculated from the DRs were 1172 mg/d for men and 1024 mg/d for women in Cohort I, and 1061 mg/d for men and 942 mg/d for women in Cohort II. The de-attenuated CCs for polyphenol intake between the DR and FFQ were 0⋅47 for men and 0⋅37 for women in Cohort I and 0⋅44 for men and 0⋅50 for women in Cohort II. Non-alcoholic beverages were the main contributor to total polyphenol intake in both men and women, accounting for 50 % of total polyphenol intake regardless of cohort and gender, followed by alcoholic beverages and seasoning and spices in men, and seasoning and spices, fruits and other vegetables in women. The present study showed that this FFQ had moderate validity and reproducibility and is suitable for use in future epidemiological studies., 2021, 10, e35, Scientific journal, True
  • Refereed, Journal of the American Geriatrics Society, Wiley, Association of coffee, green tea, and caffeine with the risk of dementia in older Japanese people, Nana Matsushita; Yuta Nakanishi; Yumi Watanabe; Kaori Kitamura; Keiko Kabasawa; Akemi Takahashi; Toshiko Saito; Ryosaku Kobayashi; Ribeka Takachi; Rieko Oshiki; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kei Watanabe; Kazutoshi Nakamura, Dec. 2021, 69, 12, 3529, 3544, Scientific journal
  • Refereed, Global Health & Medicine, National Center for Global Health and Medicine (JST), Burden of cancer attributable to modifiable factors in Japan in 2015, Manami Inoue; Mayo Hirabayashi; Sarah Krull Abe; Kota Katanoda; Norie Sawada; Yingsong Lin; Junko Ishihara; Ribeka Takachi; Chisato Nagata; Eiko Saito; Atsushi Goto; Kayo Ueda; Junko Tanaka; Megumi Hori; Tomohiro Matsuda, The This study estimated the cancer burden attributable to modifiable factors in Japan in 2015 using the best available epidemiological evidence and a standard methodology. We selected the following factors for inclusion in the estimates, namely tobacco smoking (active smoking and secondhand smoking), alcohol drinking, excess bodyweight, physical inactivity, infectious agents (Helicobacter pylori, hepatitis C virus, hepatitis B virus, human papilloma virus, Epstein-Barr virus, and human T-cell leukemia virus type 1), dietary intake (highly salted food, fruit, vegetables, dietary fiber, red meat, processed meat), exogenous hormone use, never breastfeeding and air pollution, given that these were considered modifiable, in theory at least. We first estimated the population attributable fraction (PAF) of each cancer attributable to these factors using representative relative risks of Japanese and the prevalence of exposures in Japanese around 2005, in consideration of the 10-year interval between exposure and cancer outcomes. Using nationwide cancer incidence and mortality statistics, we then estimated the attributable cancer incidence and mortality in 2015. We finally obtained the PAF for site-specific and total cancers attributable to all modifiable risk factors using this formula, with statistical consideration of the effect of overlap between risk factors. The results showed that 35.9% of all cancer incidence (43.4% in men and 25.3% in women) and 41.0% of all cancer mortality (49.7% in men and 26.8% in women) would be considered preventable by avoidance of these exposures. Infections and active smoking followed by alcohol drinking were the greatest contributing factors to cancer in Japan in 2015., 28 Feb. 2022, 4, 1, 26, 36, Scientific journal, False
  • Refereed, Journal of Epidemiology, Japan Epidemiological Association, Applicability of a web-based 24-hour dietary recall tool for Japanese populations in large-scale epidemiological studies, Yoshie Hose; Junko Ishihara; Ayaka Kotemori; Misako Nakadate; Sachiko Maruya; Junta Tanaka; Hiroshi Yatsuya; Atsuko Aoyama; Chifa Chiang; Tsuneo Konta; Takamasa Kayama; Yoshiyuki Ueno; Manami Inoue; Norie Sawada; Shoichiro Tsugane; Ribeka Takachi, 2022, Scientific journal
  • Refereed, GHM Open, National Center for Global Health and Medicine (JST), Burden of cancer attributable to insufficient vegetable, fruit and dietary fiber consumption in Japan in 2015, Junko Ishihara; Ribeka Takachi; Sarah Krull Abe; Mayo Hirabayashi; Eiko Saito; Megumi Hori; Kota Katanoda; Tomohiro Matsuda; Manami Inoue, 31 Dec. 2021, 1, 2, 70, 75, Scientific journal
  • Refereed, GHM Open, National Center for Global Health and Medicine (JST), Burden of cancer attributable to excess red and processed meat consumption in Japan in 2015, Sarah Krull Abe; Ribeka Takachi; Junko Ishihara; Mayo Hirabayashi; Eiko Saito; Megumi Hori; Kota Katanoda; Tomohiro Matsuda; Manami Inoue, 31 Dec. 2021, 1, 2, 91, 96, Scientific journal
  • Refereed, GHM Open, National Center for Global Health and Medicine (JST), Burden of cancer attributable to consumption of highly salted food in Japan in 2015, Ribeka Takachi; Junko Ishihara; Sarah Krull Abe; Mayo Hirabayashi; Eiko Saito; Megumi Hori; Kota Katanoda; Tomohiro Matsuda; Manami Inoue, 31 Dec. 2021, 1, 2, 85, 90, Scientific journal
  • Not Refereed, 家政学研究, 奈良女子大学家政学会, Nutritional epidemiolog: focused on salt intake in relation to cerebrovascular disease and gastric cancer., Takachi Ribeka, 2015, 62, 1, 52, 6
  • Scientific reports, Sugary drink consumption and risk of kidney and bladder cancer in Japanese adults., Chi Yan Leung; Sarah Krull Abe; Norie Sawada; Junko Ishihara; Ribeka Takachi; Taiki Yamaji; Motoki Iwasaki; Masahiro Hashizume; Manami Inoue; Shoichiro Tsugane, Globally, sugary drinks are widely consumed, however, few epidemiologic studies have investigated the association between sugary drink consumption and risk of kidney and bladder cancer. We examined the association of sugary drinks with risk of kidney and bladder cancer in 73,024 participants from the Japan Public Health Center-based Prospective Study who reported no history of cancer. Sugary drink consumption was assessed using a validated food frequency questionnaire at study baseline (1995-1999). Individuals were followed to December 31, 2013. Multivariable Cox proportional hazards regression models were used to calculate hazard ratios (HR) and 95% confidence intervals (CIs). During 1,069,815 person years of follow-up, 169 kidney cancer and 297 bladder cancer cases were documented. After adjusting for potential confounders, no greater risk of kidney and bladder cancer was observed. However, sugary drink consumption was positively associated with the risk of kidney cancer (HR for 100 ml/day increase in consumption was 1.11 [95% CI 1.01-1.22]) and bladder cancer (HR for 100 ml/d increase in consumption was 1.11 [95% CI 1.01-1.22]) among women after exclusion of cases diagnosed in the first three years of follow-up. In this large prospective cohort, consumption of sugary drinks was significantly associated with a small increase in hazard ratio for kidney and bladder cancer among women after exclusion of cases diagnosed within the first three years., 04 Nov. 2021, 11, 1, 21701, 21701, Scientific journal, True
  • BMC public health, Education, household income, and depressive symptoms in middle-aged and older Japanese adults., Aya Hinata; Keiko Kabasawa; Yumi Watanabe; Kaori Kitamura; Yumi Ito; Ribeka Takachi; Shoichiro Tsugane; Junta Tanaka; Ayako Sasaki; Ichiei Narita; Kazutoshi Nakamura, BACKGROUND: Income inequality has dramatically increased worldwide, and there is a need to re-evaluate the association between socio-economic status (SES) and depression. Relative contributions of household income and education to depression, as well as their interactions, have not been fully evaluated. This study aimed to examine the association between SES and depressive symptoms in Japanese adults, focusing on interactions between education and household income levels. METHODS: This cross-sectional study used data from baseline surveys of two cohort studies. Participants were 38,499 community-dwelling people aged 40-74 years who participated in baseline surveys of the Murakami cohort study (2011-2012) and Uonuma cohort study (2012-2015) conducted in Niigata Prefecture, Japan. Information regarding marital status, education level, household income, occupation, activities of daily living (ADL), and history of cancer, myocardial infarction, stroke, and diabetes was obtained using a self-administered questionnaire. Depressive symptoms were examined using the Center for Epidemiologic Studies Depression Scale (CES-D). Logistic regression analysis was used to obtain odds ratios (ORs). Covariates included age, sex, marital status, education, household income, occupation, ADL, and disease history. RESULTS: Individuals with higher education levels had lower ORs (adjusted P for trend = 0.0007) for depressive symptoms, independently of household income level. The OR of the university-or-higher group was significantly lower than that of the junior high school group (adjusted OR = 0.79). Individuals with lower household income levels had higher ORs (adjusted P for trend< 0.0001) for depressive symptoms, independently of education level. The type of occupation was not associated with depressive symptoms. In subgroup analyses according to household income level, individuals with higher education levels had significantly lower ORs in the lowest- and lower-income groups (adjusted P for trend = 0.0275 and 0.0123, respectively), but not in higher- and highest-income groups (0.5214 and 0.0915, respectively). CONCLUSIONS: Both education and household income levels are independently associated with the prevalence of depressive symptoms, with household income levels showing a more robust association with depressive symptoms than education levels. This suggests that a high household income level may offset the risk of depressive symptoms from having a low education level., 18 Nov. 2021, 21, 1, 2120, 2120, Scientific journal, True
  • Refereed, ANNALS OF NUTRITION AND METABOLISM, KARGER, CRUCIFEROUS VEGETABLE INTAKE AND LUNG CANCER RISK: A PROSPECTIVE STUDY AND A META-ANALYSIS, Nagisa Mori; Taichi Shimazu; Miho Nozue; Norie Sawada; Motoki Iwasaki; Ribeka Takachi; Ayaka Sunami; Junko Ishihara; Tomotaka Sobue; Shoichiro Tsugane, 2017, 71, 667, 667
  • The Journal of nutrition, Inverse Association between Fruit and Vegetable Intake and All-Cause Mortality: Japan Public Health Center-Based Prospective Study., Yuki Sahashi; Atsushi Goto; Ribeka Takachi; Junko Ishihara; Kumiko Kito; Rieko Kanehara; Taiki Yamaji; Motoki Iwasaki; Manami Inoue; Tsugane Shoichiro; Norie Sawada, BACKGROUND: A dose-response and nonlinear association between fruit and vegetable intake and mortality has been reported in Europe and the United States, but little is known about this association in Asia. OBJECTIVES: This study aimed to evaluate the association of fruit and vegetable intake with all-cause, cancer, cardiovascular, and respiratory disease mortality in a Japanese cohort. METHODS: In the Japan Public Health Center-based prospective study, we included 94,658 participants (mean age; 56.4 ± 7.8 years, male; 46.0%) without cancer and cardiovascular disease at baseline. Information on fruit and vegetable intake was collected using a validated food frequency questionnaire. The Cox proportional-hazards model was used to estimate hazard ratios (HR) and 95% confidence intervals (CIs) of each quintile of fruit and vegetable intake, separately, in relation to all-cause and cause-specific mortality using the first quintile as a reference. Nonlinear associations were evaluated using a likelihood ratio test, comparing a linear model with a restricted cubic spline model. RESULTS: During a median of 20.9 follow-up years (interquartile range: 19.6-23.8), 23,687 all-cause deaths were documented. After adjusting for age, sex, and potential confounding factors, fruit and vegetable intake was nonlinearly and significantly associated with lower all-cause mortality, with the fourth and fifth quintiles having comparable HRs (fruit: fourth quintile, HR: 0.91; 95%CI: 0.87, 0.95, fifth quintile, HR: 0.92; 95%CI: 0.88, 0.96; P for nonlinearity < 0.001; vegetable: fourth quintile, HR: 0.92; 95%CI: 0.88, 0.97, fifth quintile, HR: 0.93; 95%CI: 0.89, 0.98; P for nonlinearity = 0.002). Fruit intake was significantly associated with lower cardiovascular mortality (HR in the fifth quintile: 0.91; 95%CI: 0.83, 0.99; P for nonlinearity = 0.01). CONCLUSIONS: In the Japanese population, higher intake of fruits and vegetables was nonlinearly associated with decreased all-cause mortality. These findings may contribute to the establishment of dietary recommendations for enhancing life expectancy in Asia., 28 Jun. 2022, Scientific journal, True
  • Journal of the American Medical Directors Association, Leisure-Time and Non-Leisure-Time Physical Activities are Dose-Dependently Associated With a Reduced Risk of Dementia in Community-Dwelling People Aged 40-74 Years: The Murakami Cohort Study., Kaori Kitamura; Yumi Watanabe; Keiko Kabasawa; Akemi Takahashi; Toshiko Saito; Ryosaku Kobayashi; Ribeka Takachi; Rieko Oshiki; Shoichiro Tsugane; Masayuki Iki; Ayako Sasaki; Osamu Yamazaki; Kei Watanabe; Kazutoshi Nakamura, OBJECTIVE: Although physical activity (PA) in late life is considered a preventive factor for dementia, effects of different types of PAs on the development of dementia in early old age are unclear. This study aimed to determine the effect of leisure-time and non-leisure-time PAs on dementia risk in middle-aged and older adults during an 8-year follow-up. DESIGN: Prospective cohort study. SETTING AND PARTICIPANTS: Participants were 13,773 community-dwelling individuals aged 40-74 years who completed the baseline self-administered questionnaire survey of the Murakami cohort study in 2011-2013. METHODS: Main predictors were leisure-time and non-leisure-time (commute, occupational work, and housework) PAs as assessed by MET score (MET-hour/d). The outcome was newly developed dementia determined using a long-term care insurance database. Covariates included demographics, lifestyle, body size, disease history, and PA level. Hazard ratios (HRs) were calculated using Cox proportional hazards models. RESULTS: Mean age of participants was 59.0 (SD 9.3) years. Higher levels of leisure-time PA were associated with lower HRs (adjusted P for trend <.001), with all tertiles having significantly lower HRs (low: 0.71, 95% CI 0.51-0.99; medium: 0.59, 95% CI 0.43-0.81; high: 0.55, 95% CI 0.41-0.75) relative to the reference (zero). Higher quartiles of non-leisure-time PA were associated with lower adjusted HRs for dementia (adjusted P for trend < .001), with the second-fourth quartiles having significantly lower HRs (second: 0.73, 95% CI 0.54-0.98; third: 0.59, 95% CI 0.43-0.81; fourth: 0.55, 95% CI 0.41-0.75) relative to the lowest quartile. These associations were robust regardless of sex and age group. CONCLUSIONS AND IMPLICATIONS: Both leisure-time and non-leisure-time PAs are independently and robustly associated with a reduced risk of dementia., Jul. 2022, 23, 7, 1197, 1204, Scientific journal, True

MISC

  • Not Refereed, 栄養学雑誌, 栄養疫学における食事評価の現状と課題~集団の疾病予防エビデンスづくりの視点から~(日本疫学会から), 石原淳子; 高地リベカ, 03 Sep. 2018, 76, 5 Supplement, 82
  • Not Refereed, New Diet Therapy, (一社)日本臨床栄養協会, 日本人の食生活に適した減塩のポピュレーション戦略の模索, 石原淳子; 高地リベカ, Sep. 2018, 34, 2, 144, 144
  • Not Refereed, 食に関する助成研究調査報告書, すかいらーくフードサイエンス研究所, Development of an innovative method for dietary exposure assessment in epidemiological studies, 石原淳子; 高地リベカ; 井上真奈美, 2015, 28, 95, 102
  • Not Refereed, 国立がん研究センターがん研究開発費総括研究報告書(Web), 多目的コホートに基づくがん予防など健康の維持・増進に役立つエビデンスの構築に関する研究, 津金昌一郎; 澤田典絵; 笹月静; 岩崎基; 島津太一; 山地太樹; 井上真奈美; 佐藤日出夫; 六本木義光; 伊藤善信; 小松真吾; 小林一司; 塚田昌大; 塚田昌大; 崎山八郎; 伊禮壬紀夫; 大和慎一; 松井一光; 片桐幹雄; 田上豊資; 後藤尚; 仲宗根正; 一居誠; 小久保喜弘; 磯博康; 山岸良匡; 斉藤功; 溝上哲也; 国吉秀樹; 栗山進一; 中村和利; 佐々木綾子; 高地リベカ; 石原淳子; 高橋俊明; 小野剛; 小松裕和; 安田誠史; 横井左奈; 山下英俊; 祖父江友孝; 三村將; 青柳潔, 2014, 2013, 23-A-31, WEB ONLY
  • Not Refereed, The Lipid, 脂質とがんの疫学, 髙地 リベカ; 髙地リベカ; 津金昌一郎, 2014, 25, 4, 344, 51
  • Not Refereed, 月刊カレントテラピー, 減塩運動の現状と展望~にいがた減塩ルネサンス運動, 髙地 リベカ; 山﨑理; 小島美世; 永瀨吉彦; 髙地リベカ; 中村和利, 2013, 31, 10, 39, 44
  • Not Refereed, アジア諸国でのがん予防、がん検診、がん治療向上のための調査研究 平成23年度 総括・分担研究報告書, アジア諸国でのがん予防,がん検診,がん治療向上のための調査研究 東アジア地域におけるがん一次予防普及のための検証的研究, 井上真奈美; 石原淳子; 高地リベカ; 入江ふじこ, 2012, 25, 28
  • Not Refereed, 総合健康推進財団研究報告書, アジア集団における食事摂取量把握精度向上をめざした食事データベースの構築, 井上真奈美; 石原淳子; 高地リベカ, 08 Jul. 2011, 2009, 1, 8
  • Not Refereed, 新潟県医師会報, 村上コホート研究について, 中村和利; 髙地リベカ; 北村香織; 斎藤トシ子; 小林量作; 押木利英子; 佐々木綾子; 山崎理, 2011, 740, 2, 5
  • Not Refereed, 臨床栄養, 野菜果物とがん・循環器疾患について, 髙地 リベカ; 髙地リベカ; 坪野吉孝, 2008, 112, 3, 242, 3
  • Not Refereed, 栄養日本, 生活習慣病予防における栄養指導効果検証のための簡易食事調査「料理単位法」の妥当性と応用可能性, 髙地 リベカ; 君羅満; 髙地リベカ; 工藤陽子; 渡邊昌; 菅野英子; 佐藤恵子, 2006, 49, 3, 40, 2

Books etc

  • コンパクト公衆栄養学第3版, 朝倉書店, 2016, Not Refereed
  • 公衆栄養学実習, 建帛社, 2012, Not Refereed, 9784767904689

Presentations

  • Kanehara R; Goto A; Kotemori A; Mori N; Nakamura A; Sawada N; Ishihara J; Takachi R; Kawano Y; Iwasaki M; Tsugane S, Nutrients 2019 – Nutritional Advances in the Prevention and Management of Chronic Disease, Estimation of Sugar Intake and Validation Study for a Self-Administered Food Frequency Questionnaire Using Urinary Sugar in Middle-Aged Japanese Adults., Sep. 2019, True
  • Takeuchi A; Harada S; Shimazu T; Yamaji T; Sawada N; Ishihara J; Takachi R; Nakamura K; Tanaka J; Inoue M; Iwasaki M; Iso H; Sugimoto M; Hirayama A; Soga T; Tomita M; Tsugane S; Takebayashi T, 2019 Metabolomics Conference, 15th Annual Conference of the Metabolomics Society, Detect and Quantify Sources of Variability in Metabolite Measurement in a Japanese population, Jun. 2019, True
  • 神田真希、丸谷幸子、中舘美佐子、松本海保、島袋夏乃華、戸谷みのり、本多泉美、岩崎基、高地リベカ、石原淳子., 第29回日本疫学会学術総会, 家庭調味モニタリングまたは低塩調味料による減塩効果の検討のための無作為化比較試験., Feb. 2019, False
  • 山極洋子, 澤田典絵, 島津太一, 山地太樹, 後藤温, 高地リベカ, 石原淳子, 岩崎基,井上真奈美, 津金昌一郎, 第29回日本疫学会学術総会, 果物・野菜摂取と膵がん罹患の関連の検討:多目的コホート研究., Feb. 2019, False
  • 松本麻由佳、丸谷幸子、西本侑加、加藤祐子、中館美佐子、高地リベカ、石原淳子, 第28回日本疫学会学術総会, 簡易チェックシートによる食塩摂取量スクリーニングの妥当性, 01 Feb. 2018
  • 藤田みほ, 石原淳子, 八谷寛, 田中純太, 西本侑加, 丸谷幸子, 平川仁尚, 江啓発, 加藤祐子, 澤田典絵, 井上真奈美, 青山温子, 髙地リベカ, 第28回日本疫学会学術総会, 料理ベース食事調査Webシステムのコホートでの活用に関するパイロット研究~第1報 実施方法と回答状況~, Feb. 2018
  • 加藤祐子; 石原淳子; 八谷寛; 田中純太; 藤田みほ; 西本侑加; 丸谷幸子; 青山温子; 平川仁尚; 江啓発; 澤田典絵; 井上真奈美; 髙地リベカ, 第28回日本疫学会学術総会, 料理データベース食事調査Webシステムのコホートでの活用に関するパイロット研究~第2報 摂取量の推定結果~, Feb. 2018
  • 金原里恵子; 後藤温; 小手森綾香; 森渚; 中村有里; 澤田典絵; 石原淳子; 髙地リベカ; 川野因; 岩崎基; 津金昌一郎, 第28回日本疫学会学術総会, 食物摂取頻度調査票による単純糖質摂取量の妥当性および再現性, Feb. 2018
  • Mori N; Sawada N; Shimazu T; Yamamoto J; Ishihara J; Takachi R; Nakamura K; Tanaka J; Yamaji T; Iwasaki M; Iso H, European Congress of Epidemiology, IEA, Validity and reproducibility of isothiocyanate intake assessed by food frequency questionnaire in the JPHC-NEXT Validation Study: Comparison with 12-day weighed food records., Jul. 2018
  • 高地リベカ; 西本侑加; 丸谷幸子; 松本海保; 神田真希, 第65回 日本栄養改善学会学術総会, 質問票を用いた血中25(OH)D濃度予測式開発と開発集団内における妥当性, Sep. 2018
  • 石原淳子; 高地リベカ, 第65回 日本栄養改善学会学術総会<日本疫学会・日本病態栄養学会・日本栄養改善学会共催シンポジウム>「栄養改善の効果につながる食事評価法を考える」, 「栄養疫学における食事評価の現状と課題 〜集団の疾病予防エビデンスづくりの視点から〜(日本疫学会から)」, 03 Sep. 2018
  • 森渚; 島津太一; 武藤倫弘; 澤田典絵; 岩崎基; 山路大樹; 井上真奈美; 後藤温; 高地リベカ; 石原淳子; 津金昌一郎, 第77回 日本癌学会学術総会, アブラナ科野菜摂取と全死亡およびがん死亡リスクとの関連., Sep. 2018
  • Kabasawa K; Hosojima M; Ito Y; Kabasawa H; Takachi R; Nakamura K; Saito A; Tanaka J; Tsugane S; Narita I, American Society of Nephrology, Kidney Week 2018., The association with estimated dietary acid load and albuminuria in the Japanese adults., 2018
  • 髙地リベカ; 井上真奈美; 菅原由美; 辻一郎; 津金昌一郎; 伊藤秀美; 松尾恵太郎; 田中恵太郎; 玉腰暁子; 溝上哲也; 若井建志; 永田知里; 笹月静, 第27回日本疫学会学術総会, 野菜・果物摂取と全がん罹患率との関係:日本人における大規模コホートのプール解析., Jan. 2017
  • 三浦咲; 中舘美佐子; 石原淳子; 岩崎基; 中村和利; 北村香織; 加藤恵梨香; 横山悠太; 田中純太; 柏木友紀穂; 松木祐実; 髙地リベカ, 第27回日本疫学会学術総会, 家庭調味モニタリングの介入研究ベースラインにおける地域別基本特性の検討(1) ナトリウム・高塩分食品摂取., Jan. 2017
  • 中舘美佐子; 石原淳子; 岩崎基; 中村和利; 北村香織; 加藤恵梨香; 横山悠太; 田中純太; 柏木友紀穂; 松木祐美; 三浦咲; 髙地リベカ, 第27回日本疫学会学術総会, 家庭調味モニタリングの介入研究ベースラインにおける地域別基本特性の検討(2)食習慣・食嗜好., Jan. 2017
  • 丸谷幸子; 西本侑加; 髙地リベカ, 第63回日本栄養改善学会学術総会, 減塩BGMの効果を検証する食堂介入研究, Sep. 2017
  • 西本侑加; 髙地リベカ, 第63回日本栄養改善学会学術総会, 乳酸菌飲料及びヨーグルト摂取と大腸がんの関連に関する検討:システマティックレビュー, Sep. 2017
  • 高地リベカ, 第39回日本臨床栄養学会総会・第38回日本臨床栄養協会総会 第15回大連合大会・日本疫学会共催シンポジウム, 日本人の食生活と生活習慣病「食生活とがん」, 2017
  • 山岸万里奈; 髙地リベカ; 石原淳子; 石井有里; 篠澤友里江; 北村香織; 野田愛; 三代泉; 貢英彦; 澤田典絵; 島津太一; 中村和利; 田中純太; 磯博康; 笹月静; 津金昌一郎; 統合妥当性研究グルー, 第26回 日本疫学会学術総会, 味付けの好み・食行動と24時間尿中ナトリウム排泄量(5回/年)との関連, Jan. 2016
  • Takachi R; Ishihara J; Ishii Y; Ohuchi S; Saito H; Nakadate M; Yokoyama Y; Yoshida M; Takamoto E; Inoue M, th International Conference on Diet and Activity Methods, An innovative methods for dietary assessment in Japan – as a platform for the large-scale cohort consortium –, Sep. 2015, True
  • Ishihara J; Takachi R, The 25th Annual Scientific Meeting of the Japan Epidemiological Association, 2015 (Nagoya, Japan), Need for innovative dietary assessment method in Asia., Jan. 2015
  • Takachi R; Ishihara J; Nakadate M; Iwasaki M; Kitamura K; Kato E; Yokoyama Y; Tanaka J; Nakamura K, 第25回 日本疫学会学術総会, Randomized controlled crossover trial of salt reduction: (1) effect of low-sodium seasoning use., Jan. 2015
  • Nakadate M; Ishihara J; Iwasaki M; Kitamura K; Kato E; Yokoyama Y; Tanaka J; Nakamura K; Takachi R, 第25回 日本疫学会学術総会, Randomized controlled crossover trial of salt reduction: (2) effect of monitoring salt concentration.(優秀演題賞受賞), Jan. 2015
  • Kato E; Takachi R; Ishihara J; Ishii Y; Sasazuki S; Sawada N; Tanaka J; Yokoyama Y; Kitamura K; Nakamura K; Tsugane S, 第25回 日本疫学会学術総会, Validity and feasibility of Web-based self-administered FFQ developed for the JPHC-NEXT protocol., Jan. 2015
  • Yokoyama Y; Takachi R; Ishihara J; Ishii Y; Sasazuki S; Sawada N; Tanaka J; Kato E; Kitamura K; Nakamura K; Tsugane S, 第25回 日本疫学会学術総会, Short and long FFQs to rank dietary intakes in middle-aged Japanese: for the JPHC-NEXT protocol., Jan. 2015
  • Imaeda N; Ishihara J; Takachi R; Goto C; Ishii Y; Kojima S; Nanri H; Nakamura K; Yamaguchi M; Tanaka J; Fukuda N; Iso H; Hosono S; Shimazu T; Miyagawa N; Sawada N; Wakai K; Sasazuki S; Tanaka H; Tsugane S, 第25回 日本疫学会学術総会, Comparison of dietary record procedures in calibration studies for two large cohort studies., Jan. 2015
  • Nakamura K; Kitamura K; Takachi R; Saito T; Kobayashi R; Oshiki R; Watanabe Y, World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases 2015, The Murakami Cohort Study for the prevention of musculoskeletal diseases with vitamin D in Japan., Mar. 2015
  • 髙地リベカ; 吉田美佳; 高本栄一郎; 石井有里; 大内詩野; 山岸万里奈; 小田瑞希; 林えりこ; 中舘美佐子; 石原淳子, 第62回日本栄養改善学会学術集会, ICTによる自動式24時間思い出しシステムの開発-秤量法に基づく料理データベースを活用して-, Sep. 2015
  • 中舘美佐子; 石原淳子; 加藤恵梨香; 横山悠太; 髙地リベカ, 第62回日本栄養改善学会学術総会, 家庭調味モニタリング介入の効果~対象者特性別層別解析~, Sep. 2015
  • 石井有里; 髙地リベカ; 篠澤有里江; 鬼頭久美子; 石原淳子, 第61回日本栄養改善学会学術総会, 食事記録調査における調査員スキル標準化に向けての取り組み(第2報)~模擬献立を用いた推定摂取量~, Aug. 2014, False
  • 髙地リベカ; 石井有里; 篠澤有里江; 鬼頭久美子; 石原淳子, 第61回日本栄養改善学会学術総会, 食事記録調査における調査員スキル標準化に向けての取り組み(第1報)~模擬調査票を用いた確認事項達成度~, Aug. 2014, False
  • 横山悠太; 髙地リベカ; 石原淳; 岩崎基; 澤田典絵; 笹月静; 加藤恵梨香; 中村和利; 津金昌一郎, 第24回 日本疫学会学術総会, 簡易版食物摂取頻度調査票開発のための予備的検討-食品群・栄養素等の摂取量推定・妥当性検証-, Jan. 2014
  • 伊藤弘明; 岩崎基; 澤田典絵; 髙地リベカ; 春日好雄; 横山史朗; 小沼博; 西村秀紀; 草間律; 横山和仁; 津金昌一郎, 第84回 日本衛生学会学術総会, カドミウム摂取量と乳がんリスクの関連:ホルモン受容体を考慮した解析, May 2014
  • Sawada N; Iwasaki M; Inoue M; Takachi R; Sasazuki S; Yamaji T; Shimazu T; Tsugane S, The 72nd Annual Meeting of the Japanese Cancer Association, Dietary arsenic intake and subsequent risk of cancer: the Japan Public Health Center-based (JPHC) Prospective Study., Sep. 2013
  • 中村和利; 髙地リベカ; 北村香織; 斎藤トシ子; 小林量作; 押木利英子; 佐々木綾子; 山崎理; 伊木雅之, 第72回 日本公衆衛生学会総会, 加齢性運動器疾患の分子疫学コホート研究(村上鮭で元気プロジェクト), Oct. 2013
  • Nakamura K; Kitamura K; Saito T; Kobayashi R; Oshiki R; Takachi R; Sasaki A; Yamazaki O, IOF Regionals 4th Asia-Pacific Osteoporosis Meeting, Serum 25-hydroxyvitamin D levels in a population-based cohort in Japan: Murakami Cohort Study., Dec. 2013
  • 高地リベカ, 第689回 新潟医学会(特別講演), 栄養疫学と曝露評価の意義, 2013
  • 髙地リベカ; 坪野吉孝; 井上真奈美; 笹月静; 岩崎基; 津金昌一郎, 第22回 日本疫学会学術総会, 赤肉・加工肉摂取量と大腸がん罹患との関連; JPHC Study, Jan. 2012
  • 石原淳子; 髙地リベカ; 細井聖子; 石井有里; 岩崎基; 津金昌一郎, 第22回 日本疫学会学術総会, 料理画像を用いた栄養素摂取量推定の精度の検討-生体指標との比較, Jan. 2012
  • Ishihara J; Takachi R; Ishii Y; Shinozawa Y; Inoue M; Imai T; Tsugane S, 8th International Conference on Diet and Activity Methods., Development of a recipe-based database for the assessment of dietary intake in Japanese populations: Part I – framework and strategy., May 2012
  • Takachi R; Ishihara J; Ishii Y; Shinozawa Y; Inoue M; Imai T; Tsugane S, 8th International Conference on Diet and Activity Methods., Development of a recipe-based database for the assessment of dietary intake in Japanese populations: Part II – basic results., May 2012
  • 石原淳子; 髙地リベカ; 石井有里; 篠澤友里江; 鬼頭久美子; 君羅満; 今井具子, 第59回 日本栄養改善学会学術総会, 食事評価のための料理データベース開発(第1報)~データベースの基本情報について~, Sep. 2012
  • 石井有里; 髙地リベカ; 篠澤友里江; 鬼頭久美子; 君羅満; 石原淳子, 第59回 日本栄養改善学会学術総会, 食事評価のための料理データベース開発(第2報)~1食あたり料理の大きさについて~, Sep. 2012
  • Sawada N; Iwasaki M; Inoue M; Takachi R; Sasazuki S; Yamaji T; Shimazu T; Tsugane S, The 71st Annual Meeting of the Japanese Cancer Association, Long-term Dietary Cadmium Intake and Cancer Incidence: the Japan Public Health Center-based Prospective Study., Sep. 2012
  • 伊藤弘明; 岩崎基; 澤田典絵; 髙地リベカ; 春日好雄; 横山史朗; 小沼博; 西村秀紀; 草間律; 横山和仁; 津金昌一郎, 第77回 日本民族衛生学会総会, カドミウム摂取による乳がん罹患リスク -長野県における症例対照研究-, Nov. 2012
  • 高地リベカ, 第35回 高血圧学会学術総会コメディカル・メディカル合同シンポジウム, にいがた減塩ルネサンス運動, 2012
  • 髙地リベカ; 石原淳子; 岩崎基; 津金昌一郎, 第21回 日本疫学会学術総会, 検診受診者における質問紙による「みそ汁の味付け」とみそ汁濃度実測値及び食事記録法による食塩摂取量と関連, Jan. 2011
  • Takachi R; Ishihara J; Hosoi S; Iwasaki M; Tsugane S, The joint scientific meeting of the International Epidemiological Association Western Pacific Region and the 20th JEA, Validity of using digital photographic images of meals as a tool for assessing nutrient intake in middle-aged Japanese., Jan. 2010
  • 髙地リベカ; 石原淳子, 第57回 日本栄養改善学会学術総会, 日本人における塩・塩蔵食品と全がん及び循環器疾患との関連: JPHC Study, Sep. 2010
  • 鬼頭久美子; 石原淳子; 君羅満; 髙地リベカ; 細井聖子; 石井有里, 第57回 日本栄養改善学会学術総会, 料理単位による食品群・栄養素等摂取量推定の妥当性の検討, Sep. 2010
  • Ishihara J; Takachi R; Hosoi S; Iwasaki M; Tsugane S, The joint scientific meeting of the International Epidemiological Association Western Pacific Region and the 20th JEA, Validity of using digital photographic images of meals as a tool for assessing food group intake in middle-aged Japanese., Jan. 2010
  • 髙地リベカ; 石原淳子; 岩崎基; 津金昌一郎, 第19回 日本疫学会学術総会, 検診受診者における自記式半定量食物摂取頻度調査票による食品群・栄養素等摂取量推定の妥当性・再現性の検討, Jan. 2009
  • 髙地リベカ; 井上真奈美; 倉橋典江; 岩崎基; 笹月静; 石原淳子; 坪野吉孝; 津金昌一郎, 第56回 日本栄養改善学会学術総会, 日本人男性における野菜・果物摂取と前立腺がんとの関連:JPHC Study, Sep. 2009
  • 鬼頭久美子; 石原淳子; 君羅満; 髙地リベカ, 岩崎基, 第56回 日本栄養改善学会学術総会, 食事記録調査における料理別摂取頻度と食品数:料理を基本とする食事調査データベース構築のための予備検討, Sep. 2009
  • 高地リベカ, 第56回 日本栄養改善学会学術総会(奨励賞受賞講演), 実践的な料理データベース作成のための標本サイズと妥当性, Sep. 2009
  • 髙地リベカ; 井上真奈美; 石原淳子; 倉橋典江; 岩崎基; 笹月静; 磯博康; 坪野吉孝; 津金昌一郎, 第18回 日本疫学会学術総会, 野菜・果物摂取と全がん・循環器疾患罹患との関連;JPHC Study, Jan. 2008
  • 大滝直人; 馬場麻里子; 宮﨑絵里子; 羽場亮太; 君羅満; 髙地リベカ; 上杉宰世; 井沢正利; 工藤陽子, 第13回 日本健康体力栄養学会総会, 食事バランスガイドに則した中高年女性の食事の検討, Mar. 2006
  • 工藤陽子; 髙地リベカ; 関千代子; 大滝直人; 君羅満, 第53回 日本栄養改善学会学術総会, 骨密度と尿中Ca・Na排泄量との関連~閉経後期間が及ぼす影響~, Sep. 2006
  • 髙地リベカ; 上杉宰世; 大内和幸; 工藤陽子; 君羅満; 渡邊昌, 第15回 日本疫学会学術総会, 閉経後女性における血小板凝集能と食生活・脂肪酸について, Jan. 2005
  • 大滝直人; 髙地リベカ; 羽場亮太; 君羅満; 渡邊昌, 第15回 日本疫学会学術総会, 24時間尿中ミネラル排泄によるスポット尿の有効性に関する検討, Jan. 2005
  • 君羅満; 髙地リベカ; 馬場麻里子; 宮崎絵里子; 百瀬小夜; 木村一恵; 千葉歌織; 大滝直人; 工藤陽子; 渡辺昌, 第12回 日本健康体力栄養学会総会, 簡易な食事調査"料理単位法"における料理データベースの標本サイズと信頼性, Mar. 2005
  • 工藤陽子; 髙地リベカ; 大滝直人; 上杉宰世; 羽場亮太; 君羅満, 第52回 日本栄養改善学会学術総会, 簡易食事調査『料理単位法』による栄養摂取状況の把握と生活習慣病の有病数との関連, Sep. 2005
  • 君羅満; 工藤陽子; 髙地リベカ; 羽場亮太; 倉永ひさ; 関円香; 知念多美; 藤川聡子; 渡辺昌, 第14回 日本疫学会学術総会, 尿中ナトリウム, カリウム排泄量による食事調査法「料理単位法」の検討, Jan. 2004
  • 髙地リベカ; 相木浩子; 石川千尋; 石田美保子; 上杉宰世; 大内和幸; 君羅満; 渡辺昌, 第14回 日本疫学会学術総会, 一般住民における血小板凝集能検査と関連する要因について, Jan. 2004
  • 髙地リベカ; 工藤陽子; 相木浩子; 倉永ひさ; 知念多美; 君羅満, 第11回 健康体力栄養研究会総会, 簡易栄養調査法(料理単位法)の検討について: 料理成分値の妥当性, Mar. 2004
  • 君羅満; 髙地リベカ; 工藤陽子; 石川千尋; 石田美保子; 関円香; 藤川聡子, 第11回 健康体力栄養研究会総会, 簡易栄養調査法(料理単位法)の検討について ~料理ポーションサイズの検討~, Mar. 2004
  • 髙地リベカ; 工藤陽子; 菅野英子; 君羅満; 渡邊昌, 第51回 日本栄養改善学会学術総会, 簡易栄養調査法(料理単位法)の検討: 料理データベースの標本サイズ, Sep. 2004
  • 工藤陽子; 羽場亮太; 髙地リベカ; 君羅満; 渡辺昌, 第50回 日本栄養改善学会学術総会, 主要ミネラルの1日摂取量と尿中排泄量の検討, Sep. 2003
  • 荒井裕介; 谷本典隆; 八束リベカ; 高橋博子; 岩瀬靖彦; 君羅満; 高橋東生; 飯樋洋二; 赤羽正之; 五島孜郎, 第3回 日本健康体力栄養研究会, 地方都市における食生活と運動の状況について, Feb. 1996
  • 荒井裕介; 谷本典隆; 高橋博子; 八束リベカ; 岩瀬靖彦; 君羅満; 飯樋洋二; 赤羽正之, 第42回 日本栄養改善学会, 岩手県の一地域における栄養状態の経年比較について, Oct. 1995
  • Takachi R; Ishihara J; Maruya S; Tanaka J; Yatsuya H; Aoyama A; Hirakawa Y; Chiang C; Konta T; Kayama Y; Inoue M; Sawada N; Tsugane S, International Conference on Diet and Activity Methods 2020, eICDAM 2021, Automated Web-based Assessment system using Recipe-Data for Japanese (AWARDJP) – a pilot study for the middle and old age population-base cohort studies in Japan., Feb. 2021
  • 藤原紗音; 丸谷幸子; 小川冬華; 松野友香; 高地リベカ, 第67回日本栄養改善学会学術総会, 適塩ソング」BGM 放送の食塩摂取行動への影響―特定給食施設における非無作為化比較試験―, Sep. 2020
  • 鬼頭久美子; 石原淳子; 山本純平; 小手森綾香; 草野幹太; 小野澤桃子; 村岡志桜里; 丸山広達; 岡田知佳; 高地リベカ; 中村和利; 田中純太; 山地太樹; 島津太一; 石井有里; 澤田典絵; 岩崎基; 磯博康; 津金昌一郎, 第30回日本疫学会学術総会, 食事由来のトランス脂肪酸摂取量~2012-13年の摂取状態及び食物摂取頻度調査票の妥当性検証, Feb. 2020
  • 鬼頭久美子; 石原淳子; 山本純平; 細田享恒; 小手森綾香; 高地リベカ; 中村和利; 田中純太; 山地太樹; 島津太一; 澤田典絵; 岩崎基; 津金昌一郎; 磯博康; 祖父江友孝, 日本疫学会学術総会講演集(Web), 食事由来のアクリルアミド曝露量推定におけるFFQの妥当性検証, 2019, 2019, 2019
  • 金原里恵子; 金原里恵子; 後藤温; 砂見綾香; 森渚; 中村有里; 澤田典絵; 石原淳子; 石原淳子; 高地リベカ; 高地リベカ; 川野因; 岩崎基; 津金昌一郎, 日本疫学会学術総会講演集(Web), 食物摂取頻度調査票による単純糖質摂取量の妥当性および再現性に関する研究, 2018, 2018, 2018

Works

  • 多目的コホートに基づくがん予防など健康の維持・増進に役立つエビデンスの構築に関する研究-次世代コホート(新潟県地域)における栄養摂取量把握の妥当性に関する研究, Apr. 2012

Awards

  • 優秀演題, 2015, Japan
  • 奨励賞, 2009, Japan

Research Projects

  • Aug. 2019, Mar. 2024, Coinvestigator
  • May 2021, Mar. 2026, Coinvestigator
  • 01 Apr. 2021, 31 Mar. 2025, 21H03208, Coinvestigator
  • 01 Apr. 2020, 31 Mar. 2025, 20H01615, Principal investigator
  • Apr. 2018, Mar. 2022, 二重標識水法を活用した料理ベースICT食事調査システムの精度の検討, 石原 淳子, 科研費基盤(B), 0, 0, 0, Competitive research funding
  • Apr. 2018, Mar. 2022, 写真法で客観測定した食事時刻・栄養摂取とサーカディアンリズムに関する疫学研究, 石塚 理香, 科研費基盤(C), 0, 0, 0, Competitive research funding, rm:published_papers
  • 2012, 多目的コホートに基づくがん予防など健康の維持・増進に役立つエビデンスの構築に関する研究-次世代コホートにおける栄養摂取量把握の妥当性に関する研究, 津金昌一郎; 国立がん研究セ, 国立がん研究センター研究開発事業委託費, 0, 0, 0, Competitive research funding, rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers
  • 01 Apr. 2020, 31 Mar. 2025, 20H01615, Principal investigator
  • Apr. 2018, Mar. 2022, 写真法で客観測定した食事時刻・栄養摂取とサーカディアンリズムに関する疫学研究, 石塚 理香, 科研費基盤(C), 0, 0, 0, Competitive research funding, rm:published_papers
  • Apr. 2018, Mar. 2022, 二重標識水法を活用した料理ベースICT食事調査システムの精度の検討, 石原 淳子, 科研費基盤(B), 0, 0, 0, Competitive research funding
  • 2012, 多目的コホートに基づくがん予防など健康の維持・増進に役立つエビデンスの構築に関する研究-次世代コホートにおける栄養摂取量把握の妥当性に関する研究, 津金昌一郎; 国立がん研究セ, 国立がん研究センター研究開発事業委託費, 0, 0, 0, Competitive research funding, rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers
  • Apr. 2016, Mar. 2019, 日本人におけるがんの原因の寄与度:最新推計と将来予測, 井上 真奈美; 国立がん研究セ, 科研費基盤(B), 0, 0, 0, Competitive research funding, rm:published_papers;rm:published_papers;rm:published_papers;rm:published_papers
  • Apr. 2015, Mar. 2019, Principal investigator, 新たな食生活評価システムの大規模疫学研究への導入と活用に関する研究, 髙地 リベカ, 科研費基盤(B), 0, 0, 0, Competitive research funding, rm:published_papers
  • Apr. 2015, Mar. 2018, 日本人の食生活様式に適した再現可能な減塩方法を提示する無作為化比較試験, 石原 淳子, 科研費基盤(C), 0, 0, 0, Competitive research funding
  • 2015, Development of automated self-administered 24hour recall system for Japanese diet., 0, 0, 0, Competitive research funding
  • Apr. 2012, Mar. 2015, Principal investigator, 生体試料を用いた、塩味嗜好性の変容による定量的な減塩効果に関する研究, 髙地 リベカ, 科研費基盤(C), 0, 0, 0, Competitive research funding
  • Apr. 2011, Mar. 2014, 料理単位法を用いた食事評価のための標準化データベース開発, 石原 淳子, 科研費基盤(C), 0, 0, 0, Competitive research funding
  • Apr. 2010, Mar. 2012, Principal investigator, 料理データベースによる食生活調査の外的妥当性と食塩摂取量把握精度向上の検討, 髙地 リベカ, 科研費研究活動スタート支援, 0, 0, 0, Competitive research funding


Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.