IWAI Kento
| Faculty Division of Natural Sciences Research Group of Chemistry | Assistant Professor |
Last Updated :2025/07/03
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Profile Information
Name (Japanese)
IwaiName (Kana)
Kento
Research Areas
Research History
- Apr. 2024 - Present, Nara Women's University, Faculty Division of Natural Sciences, assistant professor
- Apr. 2023 - Mar. 2024, Kochi University of Technology, 理工学群, 助教, （学群名変更による）
- Apr. 2021 - Mar. 2023, Kochi University of Technology, School of Environmental Science and Engineering, 助教
- Apr. 2020 - Mar. 2021, Japan Society for the Promotion of Science, 特別研究員（DC2）
Education
- Apr. 2018 - Mar. 2021, Kyoto University, Graduate School of Science, Division of Chemistry
- Apr. 2016 - Mar. 2018, Kochi University of Technology, 大学院工学研究科, 基盤工学専攻
- Apr. 2012 - Mar. 2016, Kochi University of Technology, School of Environmental Science and Engineering, 化学・生命科学専攻
- Apr. 2009 - Mar. 2012, 高知県立幡多農業高校, 園芸システム科
Professional Memberships
Academic Activities
■Ⅱ．研究活動実績
Published Papers
- Refereed, The Journal of Organic Chemistry, American Chemical Society (ACS), Regioselective Modification Distinguishing Slight Difference between Two C–Br Bonds in 1,7-Dibromonaphthalene and Synthesis of Unsymmetric Naphthalene Derivatives, Kento Iwai; Nana Hatayama; Akitaka Ito; Nagatoshi Nishiwaki, 25 Jun. 2025, Scientific journal, 10.1021/acs.joc.5c00680
- Refereed, Journal of Oleo Science, A Straightforward Synthesis of Pinocembrin, Kento Iwai; Nagatoshi Nishiwaki, 2025, Scientific journal, 10.5650/jos.ess24245
- Refereed, Inorganic Chemistry, Unsymmetric Ir2 and RhIr Dinuclear Complexes Supported by a Linear Tetraphosphine meso-dpmppp, Showing High Reactivity for O2, H2, and HCl, Nakajima, T.; Kotani, M.; Maeda, Y.; Sato, M.; Iwai, K.; Tanase, T., 21 Oct. 2024, 63, 42, Scientific journal, 10.1021/acs.inorgchem.4c03241
- Refereed, Asian Journal of Organic Chemistry, Wiley, Non‐Electronic Activation of Anthracenes Using Steric Repulsion of the 9‐Substituent with Chloro Groups at the peri‐Positions, Annisa Indah Reza; Kento Iwai; Nagatoshi Nishiwaki, We investigated how the introduction of substituent at the 9‐ or 10‐position of the 1,8‐dichloroanthracene framework affects the horizontal and vertical distortions of the anthracene rings. The 9‐substituted anthracenes showed higher distortions than their 10‐substituted counterparts due to the steric repulsion with two chloro groups at the peri‐positions. The distortion of anthracene framework affected their reactivity. Indeed, 9‐substituted anthracenes exhibited higher reactivity to undergo the Diels–Alder reaction with maleic anhydride, which was a result of non‐electronic activation., 23 Aug. 2024, Scientific journal, 10.1002/ajoc.202400381
- Refereed, RSC Advances, Highly electron-deficient 1-propyl-3,5-dinitropyridinium: evaluation of electron-accepting ability and application as an oxidative quencher for metal complexes, Ito, A.; Kuroda, Y.; Iwai, K.; Yokoyama, S.; Nishiwaki, N., 2024, 14, 9, Scientific journal, 10.1039/d4ra00845f
- Refereed, Chemistry – An Asian Journal, Cationic Iridium‐Catalyzed Decarboxylation of Aromatic Carboxylic Acids, Reina Nonami; Yu Kishino; Tomokazu Yamasaki; Kazuya Kanemoto; Kento Iwai; Nagatoshi Nishiwaki; Kazutaka Shibatomi; Tomohiko Shirai, Practical synthetic applications of catalytic decarboxylation in producing useful molecules are limited. We report herein the cationic Ir-catalyzed decarboxylations of various electron-rich and -poor aromatic carboxylic acids to produce hydrocarbons in good yield (up to >99%). Additionally, this reaction is applicable in decarboxylative hydroarylation of bicyclic alkenes and decarboxylative fluorination, indicating the potential utility of this catalytic decarboxylation in synthetic chemistry., Sep. 2023, 18, 17, e202300533, Scientific journal, True, 10.1002/asia.202300533
- Refereed, European Journal of Inorganic Chemistry, Solid‐state Chromism of Zwitterionic Triarylmethylium Salts, Kento Iwai; Yoshiyuki Mizuhata; Tomoya Nakamura; Masato Goto; Atsushi Wakamiya; Yuichi Shimakawa; Norihiro Tokitoh, 24 Jul. 2023, Scientific journal, 10.1002/ejic.202300337
- Refereed, The Journal of Organic Chemistry, Halo-Jacobsen Rearrangement Induced by Steric Repulsion between peri-Iodo Groups, Kento Iwai; Noa Nishiguchi; Nagatoshi Nishiwaki, The naphthalene ring is distorted due to steric repulsion between iodo groups at the peri-positions. Due to the distortion, 1,8-diiodonaphthalene underwent a halo-Jacobsen rearrangement when treated with trifluoromethanesulfonic acid, producing 1,5-diiodonaphthalene and 1,4-diiodonaphthalene. In this reaction, acid-induced dehalogenative homocoupling also proceeded to form 4,4'-diiodo-1,1'-binaphthyl. The reaction selectivity could be controlled by varying the reaction temperature. DFT calculations and some control experiments revealed that these compounds were formed by different pathways., 07 Jul. 2023, 88, 13, 9409, 9412, Scientific journal, True, 10.1021/acs.joc.3c00165
- Refereed, Molecules, A Study of the Correlation between the Bulkiness of peri-Substituents and the Distortion of a Naphthalene Ring, Annisa Indah Reza; Kento Iwai; Nagatoshi Nishiwaki, Jul. 2023, 28, 14, Scientific journal, 10.3390/molecules28145343
- Refereed, Journal of Photochemistry and Photobiology, 2-Azafluorenone derivatives: Photocatalyst for oxygenation of toluene via electron transfer and hydrogen-atom transfer, Haruyasu Asahara; Yurie Horikawa; Kento Iwai; Nagatoshi Nishiwaki; Kei Ohkubo, Jun. 2023, 15, Scientific journal, 10.1016/j.jpap.2023.100184
- Refereed, The Journal of Organic Chemistry, Synthesis of Bis(functionalized) Aminals via Successive Nucleophilic Amidation and Amination, Kento Iwai; Akari Hikasa; Kotaro Yoshioka; Shinki Tani; Kazuto Umezu; Nagatoshi Nishiwaki, 17 Feb. 2023, 88, 4, 2207, 2213, Scientific journal, 10.1021/acs.joc.2c02647
- Refereed, Beilstein journal of organic chemistry, First synthesis of acylated nitrocyclopropanes., Kento Iwai; Rikiya Kamidate; Khimiya Wada; Haruyasu Asahara; Nagatoshi Nishiwaki, Although nitrocyclopropanedicarboxylic acid esters are widely used in organic syntheses, nitrocyclopropanes with an acyl group have not yet been synthesized. When adducts of β-nitrostyrene and 1,3-dicarbonyl compounds are treated with (diacetoxyiodo)benzene and tetrabutylammonium iodide, iodination occurs at the α-position of the nitro group, and the subsequent O-attack of the enol moiety leads to 2,3-dihydrofuran. Cyclopropane was successfully synthesized through C-attack as the acyl group became bulkier. The obtained nitrocyclopropane was transformed into furan upon treatment with tin(II) chloride via a ring-opening/ring-closure process., 2023, 19, 892, 900, Scientific journal, True, 10.3762/bjoc.19.67
- Refereed, ACS Omega, Synthesis of Unsymmetrical Ketones Using Chelation-Controlled Sequential Substitution of N-Triazinylamide/Weinreb Amide by Organometallic Reagents, Shotaro Hirao; Rumi Saeki; Toru Takahashi; Kento Iwai; Nagatoshi Nishiwaki; Yasushi Ohga, 27 Dec. 2022, 7, 51, 48476, 48483, Scientific journal, 10.1021/acsomega.2c06756
- Refereed, The Chemical Record, Wiley, Recent Advances in Synthesis of Multiply Arylated/Alkylated Pyridines, Annisa Indah Reza; Kento Iwai; Nagatoshi Nishiwaki, Sep. 2022, Scientific journal, 10.1002/tcr.202200099
- Refereed, Tetrahedron Letters, Efficient synthesis of α-Nitro-β-Dialdimine ligands via Equilibrium–Controlling approach, Mahiro Nakabayashi; Nagatoshi Nishiwaki; Akitaka Ito; Shotaro Hayashi; Kento Iwai, 20 Jul. 2022, 102, Scientific journal, 10.1016/j.tetlet.2022.153948
- Refereed, Molecules, Unusual Reactivities of ortho-Hydroxy-β-nitrostyrene, Kento Iwai; Khimiya Wada; Nagatoshi Nishiwaki, Jul. 2022, 27, 15, Scientific journal, 10.3390/molecules27154804
- Refereed, Synthesis, Georg Thieme Verlag {KG}, FeCl3-Promoted Facile Synthesis of Multiply Arylated Nicotinonitriles, Kento Iwai; Nagatoshi Nishiwaki; Haruka Yamauchi; Soichi Yokoyama, May 2022, 54, 10, 2480, 2486, Scientific journal, 10.1055/a-1731-9464
- Refereed, Journal of Oleo Science, A Mechanistic Study for Aziridination of Nitroalkenes Mediated by N-Chlorosuccinimide, Kento Iwai; Khimiya Wada; Feiyue Hao; Haruyasu Asahara; Nagatoshi Nishiwaki, 2022, 71, 6, 897, 903, Scientific journal, 10.5650/jos.ess21406
- Refereed, Organic & Biomolecular Chemistry, Royal Society of Chemistry ({RSC}), A new approach to 10-arylated 5H-dibenzo[b,f]azepines using syn-selective hydrohalogenation of ethynylaniline, Kento Iwai; Yusuke Mukaijo; Haruyasu Asahara; Nagatoshi Nishiwaki, 2022, 20, 28, 5543, 5550, Scientific journal, 10.1039/D2OB00950A
- Refereed, Organic & Biomolecular Chemistry, Royal Society of Chemistry ({RSC}), Development of a synthetic equivalent of α,α-dicationic acetic acid leading to unnatural amino acid derivatives via tetrafunctionalized methanes, Haruyasu Asahara; Atsushi Bonkohara; Masaya Takagi; Kento Iwai; Akitaka Ito; Kotaro Yoshioka; Shinki Tani; Kazuto Umezu; Nagatoshi Nishiwaki, 2022, 20, 11, 2282, 2292, Scientific journal, 10.1039/D1OB02482E
- Refereed, European Journal of Organic Chemistry, Metal‐Free and syn‐Selective Hydrohalogenation of Alkynes through a Pseudo‐Intramolecular Process, Haruyasu Asahara; Yusuke Mukaijo; Kengo Muragishi; Kento Iwai; Akitaka Ito; Nagatoshi Nishiwaki, 15 Nov. 2021, 2021, 42, 5747, 5755, Scientific journal, 10.1002/ejoc.202101134
- Refereed, Organometallics, Alkali-Metal-Ion-Centered Sandwich Structures of 4-Bromophenyl[tris(pentafluorophenyl)]borates and Their Synthetic Utility, Kento Iwai; Yoshiyuki Mizuhata; Norihiro Tokitoh, 08 Mar. 2021, 40, 5, 570, 577, Scientific journal, 10.1021/acs.organomet.0c00711
- Refereed, IUCrData, International Union of Crystallography ({IUCr}), 2,2-Bis[3,5-bis(dimethylamino)phenyl]-1,1,1,3,3,3-hexamethyltrisilane, Yoshiyuki Mizuhata; Kento Iwai; Norihiro Tokitoh, The title compound, C26H48N4Si3, was synthesized by the reaction of 2,2-di-chloro-tris-ilane with 3,5-bis-(di-methyl-amino)-phenyl-lithium. In the mol-ecule, the dihedral angle between the benzene rings is 57.57 (7)° and the Si-Si-Si bond angle is 110.08 (2)°. In the crystal, mol-ecules are linked via an SiC-H⋯π(ar-yl) inter-action, forming a chain along the c-axis direction., 28 Sep. 2020, 5, 9, x201299, Scientific journal, True, 10.1107/S2414314620012997
- Refereed, Bulletin of the Chemical Society of Japan, Non-electronic aromatic ring activation by simple steric repulsion between substituents in 1-methylquinolinium salt systems, Kento Iwai; Soichi Yokoyama; Haruyasu Asahara; Nagatoshi Nishiwaki, 2020, 93, 1, 50, 57, Scientific journal, 10.1246/bcsj.20190263
- Refereed, Chemical Communications, Royal Society of Chemistry ({RSC}), Development of a safely handleable synthetic equivalent of cyanonitrile oxide by 1,3-dipolar cycloaddition of nitroacetonitrile, Nagatoshi Nishiwaki; Yuta Kumegawa; Kento Iwai; Soichi Yokoyama, 2019, 55, 55, 7903, 7905, Scientific journal, 10.1039/C9CC03875B
- Refereed, Bulletin of the Chemical Society of Japan, A direct synthesis of trisubstituted allenes from propargyl alcohols via oxaphosphetane intermediates, Kento Iwai; Soichi Yokoyama; Haruyasu Asahara; Nagatoshi Nishiwaki, 2018, 91, 3, 337, 342, Scientific journal, 10.1246/bcsj.20170372
- Refereed, Journal of Oleo Science, Phosphine induced dimerization of propargyl alcohols leading to allyl propargyl ethers, Kento Iwai; Soichi Yokoyama; Haruyasu Asahara; Nagatoshi Nishiwaki, 2018, 67, 6, 773, 778, Scientific journal, 10.5650/jos.ess17277
- Refereed, Journal of Organic Chemistry, Synthesis of Functionalized 3-Cyanoisoxazoles Using a Dianionic Reagent, Kento Iwai; Haruyasu Asahara; Nagatoshi Nishiwaki, 19 May 2017, 82, 10, 5409, 5415, Scientific journal, 10.1021/acs.joc.7b00811
MISC
Research Projects
- 若手研究, 01 Apr. 2025 - 31 Mar. 2028, 25K18051, 骨格歪みの解消を駆動力とするアレーン遷移金属触媒の開発, 岩井 健人, 日本学術振興会, 科学研究費助成事業, 奈良女子大学, 4940000, 3800000, 1140000, kaken
- 特別研究員奨励費, 24 Apr. 2020 - 31 Mar. 2022, 20J12946, アニオン性置換基導入による高周期元素低配位化学種の酸化電位および構造の制御, 岩井 健人, 日本学術振興会, 科学研究費助成事業, 京都大学, 1700000, 1700000, 0, 申請者の2020年度における研究計画では、ボラヌイジル基を有する高周期典型元素低配位化学種を合成し、物性の評価を行なうことで、ボラヌイジル基の置換基効果を解明することを目標としていた。実際の研究では、ボラヌイジル基を有する双性イオン型トリアリールメチリウム塩やアクリジニウム塩およびケイ素化合物を新たに合成し、物性や反応性の評価を行なった。その結果、双性イオン型のトリアリールメチリウム塩が外部刺激に応答した色調の変化を示すことや、アクリジニウム塩が固体状態でのみ発光を示すことを明らかにした。これらの双性イオン型の色素について、単結晶X線構造解析など各種測定を行なったところ、ボラヌイジル基のイオン性相互作用に起因する特異な分子配列を示していることがわかった。この結果から、ボラヌイジル基の置換基効果として、分子内の電子的な効果のみならず、固体状態での分子間の集積構造を制御する効果があると考えられる。従って、ボラヌイジル基の新たな活用法として分子配列の制御が可能であることを示した点で本研究成果は意義深いといえる。
さらにボラヌイジル基を有する低配位ケイ素化学種の合成検討では、ボラヌイジル基を有するクロロシラン類にN-ヘテロ環状カルベン（NHC）を作用させると塩脱離を伴う求核置換反応が進行することを見出した。これは一般的なシラン類では見られない反応性であり、ボラヌイジル基を導入したことにより発現した新規な反応性であると考えられる。また、本置換反応により生成するイミダゾリオシランは更なる化学変換により多座配位性の配位場を有するアニオン性NHCへ変換できることを明らかにした。これらの一連の反応は近年注目を集めているアニオン性NHCの新規な合成法と見做せるため、合成化学的な観点から意義深い結果であると考えられる。, kaken
