研究者総覧

菊﨑 泰枝 (キクザキ ヒロエ)

  • 研究院生活環境科学系食物栄養学領域 教授
Last Updated :2021/07/07

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学位

  • 博士 生活科学, 大阪市立大学

研究キーワード

  • 食品化学 天然物化学 調理科学 給食経営管理学 食用植物 香辛料 構造解析 抗酸化性 酵素阻害 抗アレルギー 食品機能成分 

研究分野

  • 人文・社会, 家政学、生活科学
  • ライフサイエンス, 生物有機化学
  • ライフサイエンス, 食品科学

経歴

  • 2010年04月 奈良女子大学生活環境学部・教授
  • 2003年04月 - 2010年03月 大阪市立大学大学院生活科学研究科・准教授
  • 1999年04月 - 2003年03月 大阪市立大学生活科学部・講師
  • 1996年10月 - 1999年03月 大阪市立大学生活科学部・助手
  • 1984年10月 - 1996年09月 大阪市立大学生活科学部・技術職員

学歴

  • 1984年04月- 1984年09月 大阪市立大学大学院 生活科学研究科 栄養・保健学
  • 1978年04月- 1982年03月 大阪市立大学 生活科学部 食物学科

委員歴

  • 日本フードファクター学会 評議員 society

    学協会

  • 日本調理科学会 近畿支部委員 society

    学協会

  • 日本家政学会 関西支部委員 society

    学協会

  • 日本栄養・食糧学会 近畿支部評議委員 society

    学協会

  • 香料・テルペンおよび精油化学に関する討論会 役員 society

    学協会

  • 日本香辛料研究会 役員 society

    学協会

  • 日本家政学会 代議員 society

    学協会

  • 日本給食経営管理学会 評議員 society

    学協会

  • 日本農芸化学会 代議員 society

    学協会

  • 日本調理科学会 本部代議員 society

    学協会

  • 日本調理科学会 近畿支部執行部 society

    学協会

  • 日本栄養改善学会 評議員 society

    学協会

  • AOU研究会 評議委員 society

    学協会

  • 日本栄養・食糧学会 英文誌編集委員 society

    学協会

  • 日本フードファクター学会 理事 society

    学協会

  • 日本調理科学会 本部理事 society

    学協会

論文

  • Isolation of phenolic components from strawberry cultivar 'Tokun' and their inhibitory activities on recombinant human histidine decarboxylase

    2020年/0月8/日, J. Biol. Macromol., 20 (2), 33 - 39

  • Effects of cooking methods on free amino acid contents in vegetables

    Ito, H; Kikuzaki, H; Ueno, H

    2019年, J. Nutr. Sci. Vitam., 65, 264 - 271

    研究論文(学術雑誌)

  • Free Amino Acid Compositions for Fruits

    菊﨑泰枝

    2017年11月, Journal of Nutrition and Dietetic Practice, 1 (1), 1-5

  • Novel inhibitors for histidine decarboxylase from plant components

    菊﨑泰枝

    2017年08月, International Biology Review, 1 (2), 1-14

  • Inhibition of recombinant human histidine decarboxylase activity in different strawberry cultivars

    Uno, Yuichi; Nitta, Yoko; Ishibashi, Misaki; Noguchi, Yuji; Kikuzaki, Hiroe

    Strawberry fruit contains many constituents, some of which have the potential to inhibit histidine decarboxylase (HDC) activity. HDC converts L-histidine to histamine, which is associated with allergic and other biological reactions in the human body. The HDC inhibition levels were different and the component ratios varied by genotype in strawberry. Among the 11 cultivars collected locally in Japan, 'Tokun' had an approximately ten times higher inhibition ratio than the lowest cultivar. The reproducibility was confirmed using five cultivars under the same conditions in a glass greenhouse, suggesting that genotypic variation is a major factor of HDC inhibition. The potential inhibitors of HDC might be polyphenols because they showed moderate correlations with HDC inhibition rates. Among the polyphenols, the anthocyanin content possessed a moderate negative correlation. Ascorbic acid, which contributes to the overestimation of total polyphenol, did not independently inhibit HDC activity. These findings will support the identification of potential HDC inhibitors in strawberry and indicated that genotypic differences would make useful probes for inhibitor identification., 2017年06月, ACTA PHYSIOLOGIAE PLANTARUM, 39 (6), web_of_science;doi

    研究論文(学術雑誌)

  • ヒトEGFR過剰発現線虫を用いたビフィズス菌のプロバイオティクス効果

    小村 智美; Shim Jaegal; 岩城 啓子; 菊崎 泰枝; 西川 禎一

    (公社)日本栄養・食糧学会, 2017年04月, 日本栄養・食糧学会大会講演要旨集, 71回, 282 - 282

  • Construction of a free-form amino acid database for vegetables and mushrooms

    菊﨑泰枝

    2017年04月, Integrative Food, Nutrition and Metabloism, 4 (4), 1-9, doi

  • Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3 '-O-Methylepigallocatechin 3-O-Gallate

    Keiko Kobayashi; Yuki Ishizaki; Shosuke Kojo; Hiroe Kikuzaki

    Sphingomyelinases (SMases) are key enzymes involved in many diseases which are caused by oxidative stress, such as atherosclerosis, diabetes mellitus, nonalcoholic fatty liver disease, and Alzheimer's disease. SMases hydrolyze sphingomyelin to generate ceramide, a well-known pro-apoptotic lipid. SMases are classified into five types based on pH optimum, subcellular localization, and cation dependence. Previously, we demonstrated that elevation of secretory sphingomyelinase (sSMase) activity increased the plasma ceramide concentration under oxidative stress induced by diabetes and atherosclerosis in murine models. These results suggest that sSMase inhibitors can prevent the progress of these diseases. The present study demonstrated that sSMase activity was activated by oxidation and inhibited by reduction. Furthermore, we examined whether catechins inhibited the sSMase activity in a physiological plasma concentration. Among catechins, (-)-epicatechin 3-O-gallate (ECg) exhibited strong inhibitory effect on sSMase (IC50=25.7 mu m). This effect was attenuated by methylation at the 3 ''- or 4 ''-position. On the other hand, (-)-epigallocatechin 3-O-gallate (EGCg) and (-)-catechin 3-O-gallate (Cg) exhibited weaker inhibitory activity than ECg, and (-)-epicatechin and (-)-epigallocatechin did not affect sSMase activity. Additionally, one synthetic catechin, (-)-3'-O-methylepigallocatechin 3-O-gallate (EGCg-3'-O-Me), showed the strongest inhibitory effect (IC50=1.7 mu m) on sSMase. This phenomenon was not observed for (-)-4'-O-methylepigallocatechin 3-O-gallate. These results suggest that the reduction potential, the presence of the galloyl residue at the C-3 position, and the steric requirement to interact with sSMase protein are important for effective inhibition of sSMase., 2016年04月, JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 62 (2), 123 - 129, web_of_science

    研究論文(学術雑誌)

  • Inhibition of Morganella morganii Histidine Decarboxylase Activity and Histamine Accumulation in Mackerel Muscle Derived from Filipendula ulumaria Extracts

    Yoko Nitta; Fumiko Yasukata; Noritoshi Kitamoto; Mikiko Ito; Motoyoshi Sakaue; Hiroe Kikuzaki; Hiroshi Ueno

    Filipendula ulmaria, also known as meadowsweet, is an herb; its extract was examined for the prevention of histamine production, primarily that caused by contaminated fish. The efficacy of meadowsweet was assessed using two parameters: inhibition of Morganella morganii histidine decarboxylase (HDC) and inhibition of histamine accumulation in mackerel. Ellagitannins from F. ulmaria (rugosin D, rugosin A methyl ester, tellimagrandin II, and rugosin A) were previously shown to be potent inhibitors of human HDC; and in the present work, these compounds inhibited M. morganii HDC, with half maximal inhibitory concentration values of 1.5, 4.4, 6.1, and 6.8 respectively. Application of the extracts (at 2 wt%) to mackerel meat yielded significantly decreased histamine accumulation compared with treatment with phosphate-buffered saline as a control. Hence, F. ulmaria exhibits inhibitory activity against bacterial HDC and might be effective for preventing food poisoning caused by histamine., 2016年03月, JOURNAL OF FOOD PROTECTION, 79 (3), 463 - 467, doi;web_of_science

    研究論文(学術雑誌)

  • Anti-allergenic activity of polymethoxyflavones from Kaempferia parviflora

    Shoko Kobayashi; Taro Kato; Toshiaki Azuma; Hiroe Kikuzaki; Keiko Abe

    The inhibitory effects of 13 polymethoxyflavones (PMFs) obtained from Kaempferia paruiflora extracts were evaluated on RBL-2H3 cell degranulation. These flavones suppressed antigeninduced degranulation in RBL-2H3 cells. 5-Hydroxy-3,7,4',-trimethoxyflavone (KP02) and 5,3'-dihydroxy-3,7,4',-trimethoxyflavone (KP10) showed potent inhibitory activities. KP10 significantly suppressed calcium ionophores, such as A23187 and 2,5-ditert-butylhydroquinone, which promoted calcium influx from the outside of cells and from the endoplasmic reticulum, respectively. However, these activities did not fully explain the PMFs' effects. Immunoblot analysis of KPO2 and KP10 showed that the inhibitory effects were attributable to the downregulation of PLC gamma 1 kinase phosphorylation in the signaling pathways involved in degranulation. The phosphorylation levels of Syk were also suppressed by the addition of KP10. KP02 and KP10 treatment to the cells did not affect the high affinity IgE receptor (Fc epsilon RI) levels inside RBL-2H3 cells, but they suppressed the Fc epsilon RI levels in the plasma membrane. Therefore, K. parviflora PMFs have multiple degranulation mechanisms to suppress RBL-2H3 cells and would be beneficial for alleviating type I allergy symptoms. (C) 2014 Elsevier Ltd. All rights reserved., 2015年03月, JOURNAL OF FUNCTIONAL FOODS, 13, 100 - 107, doi;web_of_science

    研究論文(学術雑誌)

  • Sucrose release from agar gels: Correlation with sucrose content and rheology

    Kun Yang; Zheng Wang; Tom Brenner; Hiroe Kikuzaki; Yapeng Fang; Katsuyoshi Nishinari

    The effect of sucrose and agar concentrations on sucrose release from agar gels was investigated. It was found that the sucrose release ratio decreased with increasing sucrose concentration and with increasing fracture stress, which is consistent with previous findings. High correlation was found between the fracture stress, sucrose concentration and the sucrose release ratio. The total amount of sucrose released showed a maximum at a certain sucrose concentration, indicating that sucrose addition to enhance sweetness intensity may be ineffective or even counterproductive beyond a certain limit. (C) 2014 Elsevier Ltd. All rights reserved., 2015年01月, FOOD HYDROCOLLOIDS, 43 (1), 132 - 136, doi;web_of_science

    研究論文(学術雑誌)

  • Sucrose release from agar gels: Effects of dissolution order and the network inhomogeneity

    Kun Yang; Zheng Wang; Tom Brenner; Hiroe Kikuzaki; Yapeng Fang; Katsuyoshi Nishinari

    The effect of sucrose addition prior to or following the dissolution of agar on sucrose release from 1 wt% agar gels was studied. The order of addition was found to affect the fracture stress, fracture strain and sucrose release ratio. At sucrose concentrations below 30%, the rheology (fracture stress and strain) and structure of the gels did not depend on the order of addition of sucrose and agar. At sucrose concentrations >40%, however, the network structure of gels where sucrose was dissolved before agar addition was weaker than that of gels where sucrose was added after agar dissolution. The weaker network structure resulted in lower fracture stress and strain values. For gels prepared by adding agar to sucrose solutions, both fracture stress and strain decreased with increasing sucrose concentration in the range 40-55%. The decrease in fracture stress and strain led to an increase in the sucrose release ratio. The sucrose release ratio decreased monotonously with increasing concentration of sucrose when agar was dissolved prior to sucrose addition. The findings are discussed in relation to recent publications on gel inhomogeneity. (C) 2014 Elsevier Ltd. All rights reserved., 2015年01月, FOOD HYDROCOLLOIDS, 43 (1), 100 - 106, doi;web_of_science

    研究論文(学術雑誌)

  • The influence of agar gel texture on sucrose release

    Zheng Wang; Kun Yang; Tom Brenner; Hiroe Kikuzaki; Katsuyoshi Nishinari

    The relationship between sucrose release and texture of food gels was investigated by rheological measurements. Agar gels were selected as model food gel, and sucrose was used as a sweetener. Large deformation uniaxial compression tests were carried out at different compression speeds. The fracture stress increased with increasing agar concentration, while the concentration dependence of the fracture strain was different at different compression speeds. The size-distribution of fragments obtained after repeated compression-cycles was quantified using image analysis. The number and total surface area of fragments decreased with increasing agar concentration. Increasing the compression speed led to an initial increase followed by a monotonous decrease of both the number of fragments and their total surface area. The gel texture affected in a similar fashion both the sucrose release ratio and the total fragment surface area. The sucrose release ratio decreased with increasing agar concentration. (C) 2013 Elsevier Ltd. All rights reserved., 2014年05月, FOOD HYDROCOLLOIDS, 36, 196 - 203, doi;web_of_science

    研究論文(学術雑誌)

  • Glucosyl terpenates from the dried fruits of Prunus domestica L.

    Shin-ichi Kayano; Hiroe Kikuzaki; Sachiko Hashimoto; Kumi Kasamatsu; Takao Ikami; Nobuji Nakatani

    The chemical structures of 9 compounds isolated from the dried fruits of Prunus domestica L. were elucidated on the basis of NMR and MS analyses. Each isolated compound was determined to be scopolin (1), (3-O-cis-p-coumaroyl-beta-D-fructofuranosyl)-(2 -> 1)-alpha-D-glucopyranoside (2), 1S-(4-beta-D-glucopyranosyl- 3-methoxyphenyl)-2R-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-1,3-propanediol (3), beta-D-glucopyranosyl 9-carboxy-8-hydroxy-2,7-dimethyl-2E, 4E-nonadienate (4), beta-D-glucopyranosyl 7-carboxy2- methyl-2E, 4E-octadienate (5), 8-hydroxy-2,7-dimethyl-2E, 4E-decadienedioic acid 1-beta-D-glucopyranyl ester 10-methyl ester (6), (3-O-trans-p-coumaroyl-beta-D-fructofuranosyl)-(2 -> 1)-alpha-D-glucopyranoside (7), b-D-glucopyranosyl cinnamate (8), and 2,7-dimethyl-2E, 4E-octadienedioic acid (9), respectively. Compounds 2, 3, 4, 7, 8, and 9 were isolated from P. domestica L. for the first time, and compounds 5 and 6 were novel glucosyl terpenates. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved., 2014年05月, PHYTOCHEMISTRY LETTERS, 8, 132 - 136, doi;web_of_science

    研究論文(学術雑誌)

  • Increase in Secretory Sphingomyelinase Activity and Specific Ceramides in the Aorta of Apolipoprotein E Knockout Mice during Aging

    Keiko Kobayashi; Eri Nagata; Kazuki Sasaki; Mariko Harada-Shiba; Shosuke Kojo; Hiroe Kikuzaki

    Atherosclerosis is caused by many factors, one of which is oxidative stress. We recently demonstrated that systemic oxidative stress increased secretory sphingomyelinase (sSMase) activity and generated ceramides in the plasma of diabetic rats. In addition, we also showed that the total ceramide level in human plasma correlated with the level of oxidized low-density lipoprotein. To investigate the relationship between ceramide species and atherogenesis during aging, we compared age-related changes in ceramide metabolism in apolipoprotein E knock out mice (apoE(-/-)) and wild type mice (WT). Although the total plasma ceramide level was higher in apoE(-/-) than that in WT at all ages, it decreased with increasing age. sSMase activity increased at 65 weeks (w) of age in both strains of mice. When apoE(-/-) developed atherosclerosis at 15 w of age, C18:0, C22:0, and C24:0 ceramide levels in the apoE(-/-) aorta significantly increased. Furthermore, at 65 w of age C16:0 and C24:1 ceramide levels were significantly higher than those in WT. These results suggested that elevation in levels of specific ceramide species due to sSMase activity contributed to atherogenesis during aging., 2013年07月, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 36 (7), 1192 - 1196, web_of_science

    研究論文(学術雑誌)

  • Inhibitory activity of Filipendula ulmaria constituents on recombinant human histidine decarboxylase

    Yoko Nitta; Hiroe Kikuzaki; Toshiaki Azuma; Yuan Ye; Motoyoshi Sakaue; Yoshiki Higuchi; Hirohumi Komori; Hiroshi Ueno

    Histidine decarboxylase (HDC) catalyses the formation of histamine, a bioactive amine. Agents that control HDC activity are beneficial for treating histamine-mediated symptoms, such as allergies and stomach ulceration. We searched for inhibitors of HDC from the ethyl acetate extract of the petal of Filipendula ulmaria, also called meadowsweet. Rugosin D, rugosin A, rugosin A methyl ester (a novel compound), and tellimagrandin II were the main components these 4 ellagitannins exhibited a non-competitive type of inhibition, with Ki values of approximately 0.35-1 μM. These Ki values are nearly equal to that of histidine methyl ester (Ki = 0.46 μM), an existing substrate analogue inhibitor. Our results show that food products contain potent HDC inhibitors and that these active food constituents might be useful for designing clinically available HDC inhibitors. © 2012 Elsevier Ltd. All rights reserved., 2013年06月01日, Food Chemistry, 138 (2-3), 1551 - 1556, doi;pubmed

    研究論文(学術雑誌)

  • 給食経営管理実習中の消費電力の推算及び実測によるエネルギー教育の試み

    菊﨑泰枝; 山形純子; 小林慧子; 伊與田浩志

    2013年05月, 日本給食経営管理学会誌, 7 (1), 31-42

  • Isoflavone C-glycosides isolated from the root of kudzu (Pueraria lobata) and their estrogenic activities

    Shin-ichi Kayano; Yoko Matsumura; Yoko Kitagawa; Mayumi Kobayashi; Asuka Nagayama; Nami Kawabata; Hiroe Kikuzaki; Yoshimi Kitada

    The chemical structures of six isoflavones (1-6) isolated from the kudzu root (Pueraria lobata) were elucidated on the basis of the NMR and MS analyses to be four isoflavone C-glycosides as 6 ''-O-alpha-D-glucopyranosylpuerarin (1), puerarin (2), 3'-methoxypuerarin (3), 6 ''-O-alpha-D-apiofranosylpuerarin (4), and two aglycons as biochanin A (5) and formononetin (6), respectively. The estrogenic activities of isolated compounds and related isoflavones were evaluated using a yeast two-hybrid assay. Genistein exhibited the highest activity among the evaluated compounds at 10(-6) M followed by daidzein (10(-5) M), baiochanin A (5) (10(-5) M), daidzin (10(-5) M), 3',4',7-trihydroxyisoflavone (10(-3) M), and formononetin (6) (10(-2) M). The isoflavone C-glycosides (1-4) and 4',7-dimethoxyisoflavone showed no activities. In these results, it was found that the addition of 8-C-glucose or 3'-hydroxyl group to daidzein skeleton, or the substitution of hydroxyl functions to methoxyl groups, decreased the estrogenic activity of daidzein, on the other hand, the addition of 7-O-glucose moiety had no influence on the activity. (C) 2012 Elsevier Ltd. All rights reserved., 2012年09月, FOOD CHEMISTRY, 134 (1), 282 - 287, doi;web_of_science

    研究論文(学術雑誌)

  • Identification of a Novel Glycoside, Leptosin, as a Chemical Marker of Manuka Honey

    Yoji Kato; Natsuki Umeda; Asuna Maeda; Daiki Matsumoto; Noritoshi Kitamoto; Hiroe Kikuzaki

    As a preliminary study, we have found that honey from manuka (Leptospermum scoparium) in New Zealand inhibits myeloperoxidase (MPO) activity. In this study, using a chromatographic technique, we isolated two active compounds for MPO-inhibition from manuka honey. One is methyl syringate (MSYR), and the other was identified as a novel glycoside of MSYR, methyl syringate 4-O-beta-D-gentiobiose, which has been named "leptosin" after the genus Leptospermum. The amount of the glycoside ranged from 0.2 to 1.2 mu mol/g honey. Leptosin was only found in honeys from the Oceania region, and abundantly in manuka honey including jelly bush honey from Leptospermum polygalifolium in Australia. Therefore, leptosin may be a good chemical marker for manuka honey. Interestingly, the concentration of leptosin in manuka honey was positively correlated with the unique manuka factor (UMF) value, which is expressed as phenol equivalents of its bactericidal activity., 2012年04月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 60 (13), 3418 - 3423, doi;web_of_science

    研究論文(学術雑誌)

  • Antimutagenic and α-glucosidase inhibitory effects of constituents from Kaempferia parviflora

    菊﨑泰枝

    研究の立案、筆頭著者の研究指導、論文作成を行った, 2011年03月, FOOD CHEMISTRY, 125 (2), 471 - 475, doi;web_of_science

    研究論文(学術雑誌)

  • 大量調理施設におけるエネルギー消費意識の実態調査と管理栄養士養成課程の学内給食実習におけるエネルギー消費量「見える化」の試み

    菊﨑泰枝; 山形純子他

    2011年03月, 日本給食経営管理学会誌, 5 (1), 29-37

  • Inhibitory Activity of Pimenta dioica Extracts and Constituents on Recombinant Human Histidine Decarboxylase

    菊﨑泰枝

    2009年01月, Food Chemistry, 113, 445-449

  • Phenolic Glycosides from Kaempferia parviflora

    菊﨑泰枝

    2008年10月, Phytochemistry, 69, 2743-2748

  • Phenolic glycosides from berries of Pimenta dioica

    Hiroe Kikuzaki; Yoshiko Miyajima; Nobuji Nakatani

    Four new phenolic glycosides, (27hydroxy-3-methoxy-5-allyl)phenyl beta-D-(6-O-E-sinapoyl)glucopyranoside (1), (1'R,5'R)-5-(5-carboxymethyl-2-oxocyclopentyl)-3Z-pentenyl beta-D-(6-O-galloyl)glucopyranoside (2), (S)-alpha-terpinyl [alpha-L-(2-O-galloyl)arabinofuranosyl]-(1 -> 6)-beta-D-glucopyranoside (3), and (R)-alpha-terpinyl [alpha-L-(2-O-galloyl)arabinofuranosyl]-(1 -> 6)-beta-D-glucopyranoside (4), were isolated from the berries of Pimenta dioica together with eight known flavonoids. The structures of 1-4 were elucidated on the basis of MS and NMR data and enzymatic hydrolysis. All four glycosides showed radical - scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals., 2008年05月, JOURNAL OF NATURAL PRODUCTS, 71 (5), 861 - 865, doi;web_of_science

    研究論文(学術雑誌)

  • Ecdysteroids act as inhibitors of calf skin collagenase and oxidative stress

    Robert Yawadio Nsimba; Hiroe Kikuzaki; Yotaro Konishi

    Three new phytoecdysteroids have been isolated from the seeds of Chenopodium quinoa and structurally identified as 20,26-dihydroxy, 28-methyl ecdysone, 20,26-dihydroxy, 24(28)-dehydro ecdysone, and 20-hydroxyecdysone 22-glycolate using serial chromatographic and spectroscopic methods. Both previously reported compounds and newly identified phytoecdysteroids were evaluated for their inhibitory effect on calf skin collagenase, as this enzyme is involved in aging skin diseases. Their effectiveness on scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, as well as in chelating the iron metal ions was also investigated. All isolated compounds demonstrated a higher potency to inhibit this matrix metalloproteinase and to chelate the iron ion, both with respect to the number of carbonyl groups bearing their carbon skeleton, suggesting that their mechanism of action involves their ability to coordinate both ions (either the zinc ion of the catalytic domain of collagenase or the iron ion), acting as an electron donor. The DPPH-scavenging ability was hydroxyl dependent. Satisfactory results obtained from the enzyme in vitro experiment were further supported by the gel electrophoresis. These results indicate that ecdysteroids might be considered as potent chemical agents to prevent or delay both collagenase-related skin damages and oxidative stress. (C) 2008 Wiley Periodicals, Inc., 2008年, JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 22 (4), 240 - 250, doi;web_of_science

    研究論文(学術雑誌)

  • Antioxidant activity of various extracts and fractions of Chenopodium quinoa and Amaranthus spp. seeds

    Robert Yawadio Nsimba; Hiroe Kikuzaki; Yotaro Konishi

    The antioxidant potency of various extracts and fractions from Chenopodium quinoa and Amaranthus sp. was evaluated using three established methods, specifically the DPPH scavenging activity, FRAP, and P-carotene bleaching assays. Satisfying results were obtained, which lead to expect the use of these seeds as health-promoting ingredients. The antioxidant activity was less correlated to the phenolics content suggesting that non-phenolic compounds might play major free radicals scavenging activity in studied plant materials. (c) 2007 Elsevier Ltd. All rights reserved., 2008年01月, FOOD CHEMISTRY, 106 (2), 760 - 766, doi;web_of_science

    研究論文(学術雑誌)

  • Chemical constituents of cape aloe and their synergistic growth-inhibiting effect on Ehrlich ascites tumor cells

    Saeda Kametani; Akiko Kojima-Yuasa; Hiroe Kikuzaki; David Opare Kennedy; Mayumi Honzawa; Isao Matsui-Yuasa

    The constituents of cape aloe were investigated after a preliminary screening of the growth-inhibiting effect on Ehrlich ascites tumor cells (EATC) of several extracts of this plant. Ten compounds were isolated from the dichloromethane (CH2Cl2) extract that showed the strongest activity, and their structures were elucidated as aloe-emodin (1), p-hydroxybenzaldehyde (2), p-hydroxyacetophenone (3), pyrocatechol (4), 10-oxooctadecanoic acid (5), 10-hydroxyoctadecanoic acid (6), methyl 10-hydroxyoctadecanoate (7), 7-hydroxy-2,5-dimethylchromone (8), furoaloesone (9), and 2-acetonyl-8-(2-furoylmethyl)-7-hydroxy-5-methylchromone (10) based on MS and various NMR spectroscopic techniques. Compounds 2-7 were isolated for the first time from cape aloe. Compounds 4-7 and 10 showed a significant growth-inhibiting effect, and compound 1 exhibited a remarkable synergistic effect on compounds 8-10, which was not observed with the treatment by each compound alone on EATC. These results suggest that the strong growth-inhibiting effect of the CH2Cl2 extract was dependent not on one compound alone, but on the synergistic effect from the combination of compound 1 and the other compounds., 2007年05月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71 (5), 1220 - 1229, doi;web_of_science

    研究論文(学術雑誌)

  • Food Components Inhibiting Recombinant Human Histidine Decarboxylase Activity

    菊﨑泰枝

    2007年02月, J. Agric. Food Chem., 55 (2), 299-304

  • 給食経営管理実習における衛生管理に対するHACCP概念導入の教育効果について 作業過程における一般生菌数の推移と作業動線の実態調査から

    菊崎 泰枝; 御前 加奈; 戸嶋 ひろ野; 松村 羊子; 荻布 智恵; 西川 禎一; 尾立 純子

    栄養士法一部改正以前の旧カリキュラムで実施した給食管理実習と改正後の新カリキュラムで実施した給食経営管理実習において、HACCP(危害分析重要管理点)概念を導入した衛生教育を行うことが実際の実習の場にどのような影響を与えるかを検証した。使用設備の一般生菌数の推移はHACCP教育の有無にかかわらず、作業の清潔度に応じた推移を示した。手指の一般生菌数の推移を調べた結果からはHACCP教育の導入による手指の洗浄改善効果は認めなかった。作業動線および温度管理状況に対しては、HACCP教育の効果が顕著に認めた。, 大阪市立大学大学院生活科学研究科, 2007年03月, 生活科学研究誌, 5, 35 - 44, jamas_url;jamas_url

  • 特定給食施設(病院)における人件費率、食材料費の実態

    赤尾 正; 菊﨑泰枝; 藤原政嘉

    2006年12月, 生活科学研究誌, 5, 45-50

  • Terpenoids and a diarylheptanoid from Zingiber ottensii

    Kayo Akiyama; Hiroe Kikuzaki; Takako Aoki; Akiko Okuda; Nordin H. Lajis; Nobuji Nakatani

    Four new terpenoids and a diarylheptanoid were isolated together with 16 known compounds from rhizomes of Zingiber ottensii. The structures of the new compounds were determined to be 1,10,10-trimethylbicyclo[7,4,0] tridecane-3,6-dione (1), (E)-14-hydroxy-15-norlabda-8(17), 12-dien-16-al (2), (E)-labda-8(17), 12,14-trien-15(16)-olide (3), (E)-14,-15,16- trinorlabda-8(17), 11-dien-13-oic acid (4), and rel-(3R, 5S)-3,5-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(3, 4-dihydroxyphenyl) heptane (5) by spectroscopic evidence., 2006年11月, JOURNAL OF NATURAL PRODUCTS, 69 (11), 1637 - 1640, doi;web_of_science

    研究論文(学術雑誌)

  • Capsaicinol: Synthesis by allylic oxidation and its effect on TRPV1-expressing cells and adrenaline secretion in rats

    Kenji Kobata; Takahito Iwasawa; Yusaku Iwasaki; Akihito Morita; Yuichi Suzuki; Hiroe Kikuzaki; Nobuji Nakatani; Tatsuo Watanabe

    Capsaicinol is an ingredient of hot red pepper. In this study, we developed a novel method for capsaicinol synthesis and examined capsaicinol's physiological effects on capsaicin receptor (TRPV1)-related actions. Allylic oxidation of capsaicin by palladium acetate (Pd(OAc)(2)) resulted in the formation of (+/-)-capsaicinol acetate at a 7.2% yield in a single step. The effectiveness of (+/-)-capsaicinol in TRPV1 activation (EC50 = 1.1 mu M) was found to be weaker than that of capsaicin (EC50 = 0.017 mu M), whereas the efficacy of (+/-)-capsaicinol reached 15% of that of capsaicin. Intravenous administration of (+/-)-capsaicinol in anesthetized rats dose-dependently enhanced adrenaline secretion from the adrenal gland. The response to a 5mg/kg-dose of (+/-)-capsaicinol was comparable to that of a 0.05 mg/kg-dose of capsaicin. The relative pungency of capsaicinol to capsaicin was coincident with the relative effectiveness in. inducing these TRPV1-related actions., 2006年08月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 70 (8), 1904 - 1912, doi;web_of_science

    研究論文(学術雑誌)

  • Chemical Constituents of Piper retrofractum Vahl and Their Antioxidant and Radical Scavenging Activities

    菊﨑泰枝

    2005年12月, ITE Letters on Batteries, New Technologies & Medicine, 6, 566-573

  • Antioxidative constituents of Etlingera elatior

    H Mohamad; NH Lajis; F Abas; AM Ali; MA Sukari; H Kikuzaki; N Nakatani

    Phytochemical studies on the rhizomes of Etlingera elatior have resulted in the isolation of 1,7-bis(4-hydroxyphenyl)-2,4,6-heptatrienone (1), demethoxycurcumin (2), 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one (3), 16-hydroxylabda-8(17),11,13-trien-15,16-olide (4), stigmast-4-en-3-one, stigmast-4-ene-3,6-dione, stigmast-4-en-6beta-ol-3-one, and 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol. Compounds 1 and 4 are new, and their structures were elucidated by analysis of spectroscopic data. Diarylheptanoids 1-3 were found to inhibit lipid peroxidation in a more potent manner than alpha-tocopherol., 2005年02月, JOURNAL OF NATURAL PRODUCTS, 68 (2), 285 - 288, doi;web_of_science

    研究論文(学術雑誌)

  • Screening of Spice and Herb Extracts for Cytotoxic Activity against Ehrlich Ascites Tumor Cells and DPPH Radical Scavenging Activity

    菊﨑泰枝

    2004年12月, ITE Letters on Batteries, New Technologies & Medicine, 5, 67-75

  • DPPH free radical scavenger components from the fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae)

    H Mohamad; F Abas; D Permana; NH Lajis; AM Ali; MA Sukari; TYY Hin; H Kikuzaki; N Nakatani

    The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2',3',4',6'-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC50 value of 55 mum. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3- one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis., 2004年11月, ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, 59 (11-12), 811 - 815, web_of_science

    研究論文(学術雑誌)

  • Constituents of the Leaves of Peucedanum japonicum Thunb. and Their Biological Activity

    菊﨑泰枝

    2004年04月, J. Agric. Food Chem., 52, 445-450

  • A new bipyrrole and some phenolic constituents in prunes (Prunus domestica L.) and their oxygen radical absorbance capacity (ORAC)

    S Kayano; H Kikuzaki; T Ikami; T Suzuki; T Mitani; N Nakatani

    Isolation and structural elucidation of prune constituents were performed and total 10 compounds were determined by NMR and MS analyses. A novel compound was identified to be 2-(5-hydroxymethyl-2',5'dioxo-2',3',4',5'-tetrahydro-l'H-1,3'-bipyrrole)carbalde- hyde, and 7 phenolic compounds were isolated from prunes for the first time. In addition, antioxidant activity of them was evaluated on the basis of the oxygen radical absorbance capacity (ORAC)., 2004年04月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 68 (4), 942 - 944, web_of_science

    研究論文(学術雑誌)

  • 大量調理に使用する粉末出しのミネラル含量-学校給食から-

    菊﨑泰枝; 尾立純子; 福田直子; 菊崎泰枝; 湯浅(小島)明子; 船坂邦弘

    2004年04月, 食生活研究, 24, 40-46

  • Abscisic Acid Related Compounds and Lignans in Prunes (Prunus domestica L.) and Their Oxygen Radical Absorbance Capacity (ORAC)

    菊﨑泰枝

    2004年03月, J. Agric. Food Chem., 52, 344-349

  • Antioxidant properties of gingerol related compounds from ginger

    Y Masuda; H Kikuzaki; M Hisamoto; N Nakatani

    Ginger (Zingiber officinale Roscoe) shows an antioxidant activity, and we have been engaging to determine the structures of more than 50 antioxidants isolated from the rhizomes of ginger. The isolated antioxidants are divided into two groups; gingerol related compounds and diarylheptanoids. In this study, structure-activity relationship of gingerol related compounds was evaluated. Gingerol related compounds substituted with an alkyl group bearing 10-, 12- or 14-carbon chain length were isolated from the dichloromethane extract of rhizomes using repeated chromatographic techniques. The antioxidant activities of these compounds were evaluated by the following measurements; 1) 1, 1 -diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, 2) inhibitory effect on oxidation of methyl linoleate under aeration and heating by the Oil Stability Index (OSI) method, and 3) inhibitory effect on oxidation of liposome induced by 2,2 -azobis(2-amidinopropane)dihydrochloride (AAPH). These results suggested that the substituents on the alkyl chain might contribute to both radical scavenging effect and inhibitory effect of autoxidation of oils, while inhibitory effects against the AAPH-induced peroxidation of liposome was somewhat influenced by the alkyl chain length; the antioxidant activity might be due to not only radical scavenging activity of antioxidants but also their affinity of the antioxidants to the substrates., 2004年, BIOFACTORS, 21 (1-4), 293 - 296, web_of_science

    研究論文(学術雑誌)

  • Antioxidative polyphenols from berries of Pimenta dioica

    Y Miyajima; H Kikuzaki; M Hisamoto; N Nakatani

    The ethyl acetate-soluble part of allspice, berries of Pimenta dioica, showed strong antioxidant activity and radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazy] (DPPH) radical. From the ethyl acetate-soluble part, two new compounds, 5-galloyloxy-3,4-dihydroxypentanoic acid and 5-(5-carboxymethyl-2-oxocyclopentyl)-3Z-pentenyl 6-O-galloyl-beta-D-glucoside were isolated together with 11 known polyphenols by repeated column chromatography. Their structures were elucidated on the basis of MS and various NMR spectroscopic data.All isolated compounds were evaluated for antioxidative effects on oxidation of methyl linoleate under aeration and heating, and on peroxidation of liposome induced by 2,1-azobis-(2-amidinopropane)dihydrocloride (AAPH) as a water-soluble initiator along with their radical -scavenging activity against DPPH. Quercetin and its glycosides showed remarkable activity for scavenging DPPH radical and inhibiting peroxidation of liposome. Two new compounds also exhibited strong DPPH radical -scavenging activity and inhibitory effect on the peroxidation of liposome as myricetin., 2004年, BIOFACTORS, 21 (1-4), 301 - 303, web_of_science

    研究論文(学術雑誌)

  • Antioxidant properties of prunes (Prunus domestica L.) and their constituents

    SI Kayano; H Kikuzaki; NF Yamada; A Aoki; K Kasamatsu; Y Yamasaki; T Ikami; T Suzuki; T Mitani; N Nakatani

    Prunes contain large amounts of phenolics and show high antioxidant activity. The aim of this study is to clarify the contents of caffeoylquinic acid (CQA) isomers, and to estimate the contribution of these isomers to the antioxidant activity of prunes. Furthermore, structural elucidation and evaluation of antioxidant activity of prune components were also performed. CQA isomers in prunes were quantified by HPLC analysis, and it has become apparent that prunes contain relatively high amount of 4-O-caffeoylquinic acid. The contribution of CQA isomers to the antioxidant activity of prunes was revealed to be 28.4% on the basis of oxygen radical absorbance capacity (ORAC); hence, it was indicated that residual ORAC is dependent on unknown antioxidant components. Total 28 compounds were isolated and their structures were elucidated by NMR and MS analyses. Four abscisic acid related compounds, a chromanon, and a bipyrrole were novel. Each CQA isomer in prunes showed high antioxidant activities when measured by the oil stability index (OSI) method, O-2(-) scavenging activity, and ORAC. Other isolated compounds such as hydroxycinnamic acids, benzoic acids, coumarins, lignans, and flavonoid showed high ORAC values. Furthermore, a novel chromanon indicated a remarkable synergistic effect on ORAC of CQA isomers., 2004年, BIOFACTORS, 21 (1-4), 309 - 313, web_of_science

    研究論文(学術雑誌)

  • Antioxidant and antitumor promoting activities of the flavonoids from Hedychium thyrsiforme

    Jasril; LY Mooi; NH Lajis; AM Ali; MA Sukari; AA Rahman; AG Othman; H Kikuzaki; N Nakatani

    Five flavonoids, including 3,7,4'-trimethoxy-5-hydroxyflavone (1), 3,4'-dimethoxy-5,7-dihydroxyflavone (2), 5,7,4'-trimethoxy-3-hydroxyflavone (3), 3,5,7,4'-tetramethoxyflavone (4), and 7,4'-dimethoxy-3,5-dihydroxyflavone (5), were isolated from the rhizome of Hedychium thyrsiforme and assayed for antioxidant and antitumor promoting activities. The antioxidant assays showed that 5,7,4'-trimethoxy-3-hydroxyflavone, 7,4'-dimethoxy-3,5-dihydroxyflavone and 3,4'-dimethoxy-5,7-dihydroxyflavone had strong activities. Only two compounds, 5,7,4'-trimethoxy-3-hydroxyflavone and 7,4'-dimethoxy-3,5-dihydroxyflavone, were found to be strong 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavengers with fifty percent inhibition concentration (IC50) values of 92 and 119 muM, respectively. Antitumor promoting assays indicated that all the flavonoids showed strong inhibition activity towards Epstein-Barr virus (EBV) activation in Raji cells., 2003年10月, PHARMACEUTICAL BIOLOGY, 41 (7), 506 - 511, web_of_science

    研究論文(学術雑誌)

  • Comparison of antioxidative properties of carbazole alkaloids from Murraya koenigii leaves

    Y Tachibana; H Kikuzaki; NH Lajis; N Nakatani

    A new dimeric carbazole alkaloid, 8,10'-[3,3',11,11'-tetrahydro-9,9'-dihydroxy-3,3',5,8'-tetramethyl-3,3'-bis(4-methyl-3-pentenyl)]bipyrano[3,2-a]carbazole (12), was isolated from the CH2Cl2 extract of Murraya koenigii together with six known carbazole alkaloids, koenimbine (6), O-methylmurrayamine A (7), O-methylmahanine (8), isomahanine (9), bismahanine (10), and bispyrayafoline (11). Their structures were determined on the basis of H-1 and C-13 NMR spectroscopic and mass spectrometric (MS) data. The antioxidative properties of 12 carbazole alkaloids isolated from leaves of M. koenigii were evaluated on the basis of the oil stability index together with their radical scavenging ability against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical. On the basis of the lag time to reach a steady state, the 12 carbazoles were classified into three groups. It is suggested that an aryl hydroxyl substituent on the carbazole rings plays a role in stabilizing the thermal oxidation and rate of reaction against DPPH radical., 2003年10月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 51 (22), 6461 - 6467, doi;web_of_science

    研究論文(学術雑誌)

  • Quantification of Quinic Acid in Prunes (Prunus domestica L.) by HPLC Analysis

    菊﨑泰枝

    2003年10月, ITE Letters on Batteries, New Technologies & Medicine, 4, 639-644

  • Antioxidant compounds from the leaves of Peucedanum japonicum Thunb

    M Hisamoto; H Kikuzaki; H Ohigashi; N Nakatani

    Seventeen compounds were isolated from the n-butanol soluble fraction of the leaves of Peucedanum japonicum Thunb. On the basis of MS and various NMR spectroscopic techniques, the structures of the isolated compounds were determined as isoquercitrin (1), rutin (2), 3-O-caffeoylquinic acid (3), 4-O-caffeoylquinic acid (4), 5-O-caffeoylquinic acid (5), cnidioside A (6), praeroside II (7), praeroside III (8), apterin (9), esculin (10), (R)-peucedanol (11), (R)-peucedanol 7-O-beta-D-glucopyranoside (12), L-tryptophan (113), uracil (114), guanosine (115), uridine (116), and thymidine (117). All compounds except 11 and 12 were isolated for the first time from P. japonicum. Several isolated compounds were quantified by high-performance liquid chromatography analysis. In addition, all isolated compounds were examined for radical scavenging on 1,1-diphenyl-2-picrylhydrazyl radical and for inhibition of oxidation of liposome induced by 2,2'-azobis(2-amidinopropane)dihydrochloride. Compounds 2-5 were found to be the major potent constituents, which contribute to the antioxidant activity of P. japonicum leaves., 2003年08月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 51 (18), 5255 - 5261, doi;web_of_science

    研究論文(学術雑誌)

  • Conformational Isomers of 3-O-Caffeoylquinic Acid Isolated from Prunes (Prunus domestica L.) and Their Antioxidant Activity

    菊﨑泰枝

    2003年08月, ITE Letters on Batteries, New Technologies & Medicine, 4, 478-484

  • Lack of Inhibitory Effects of Coumaperine from Pepper on the Promotion Stage of Chemical Hepatocarcinogenesis in the Rat

    菊﨑泰枝

    2003年08月, J. Toxicol. Pathol., 16, 161-164

  • The Antioxidative Components from Alpinia nutans

    菊﨑泰枝

    2003年07月, Pharmaceutical Biology, 41, 7-9

  • Quantitative Evaluation of Antioxidant Components in Prunes (Prunus domestica L.)

    菊﨑泰枝

    2003年05月, J. Agric. Food Chem., 51, 1480-1485

  • 沖縄産香辛植物の食中毒菌増殖抑制作用

    菊﨑泰枝; 西川禎一; 森光康次郎

    2003年04月, 生活科学研究誌, 1, 11-16

  • Sphingolipid and other constituents from almond nuts (Prunus amygdalus Batsch)

    SM Sang; H Kikuzaki; K Lapsley; RT Rosen; N Nakatani; CT Ho

    One sphingolipid, 1-O-beta-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2R)-2-hydroxyhexadecanoylamino]-4,8-octadecadiene-1,3-diol, and four other constituents, beta-sitosterol, daucosterol, uridine, and adenosine, have been isolated from the nuts of almond (Prunus amygdalus). Complete assignments of the proton and carbon chemical shifts for the sphingolipid were accomplished on the basis of high-resolution 1D and 2D NMR. data. All of these compounds are being reported from almond nuts (P. amygdalus) for the first time., 2002年07月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 50 (16), 4709 - 4712, doi;web_of_science

    研究論文(学術雑誌)

  • Antifungal Garcinia Acid Esters from the Fruits of Garcinia atroviridis

    菊﨑泰枝

    2002年05月, Z. Naturforsch, 57c, 291-295

  • Antixoidant Activity of Prune (Prunus domestica L.) Constituents and a New Synergist

    菊﨑泰枝

    2002年05月, J. Agric. Food Chem., 50, 3708-3712

  • Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method

    K Miura; H Kikuzaki; N Nakatani

    A new abietane diterpenoid, 12-O-methyl carnosol (2), was isolated from the leaves of sage (Salvia officinalis L.), together with 11 abietane diterpenoids, 3 apianane terpenoids, 1 anthraquinone, and 8 flavonoids. Antioxidant activity of these compounds along with 4 flavonoids isolated from thyme (Thymus vulgaris L.) was evaluated by the oil stability index method using a model substrate oil including methyl linoleate in silicone oil at 90 degreesC. Carnosol, rosmanol, epirosmanol, isorosmanol, galdosol, and carnosic acid exhibited remarkably strong activity, which was comparable to that of alpha-tocopherol. The activity of miltirone, atuntzensin A, luteolin, 7-O-methyl luteolin, and eupafolin was comparable to that of butylated hydroxytoluene. The activity of these compounds was mainly due to the presence of ortho-dihydroxy groups. The 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity of these compounds showed the similar result., 2002年03月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 50 (7), 1845 - 1851, doi;web_of_science

    研究論文(学術雑誌)

  • Antioxidant properties of ferulic acid and its related compounds

    H Kikuzaki; M Hisamoto; K Hirose; K Akiyama; H Taniguchi

    Antioxidant activity of 24 ferulic acid related compounds together with 6 gallic acid related compounds was evaluated using several different physical systems as well as their radical scavenging activity. The radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) decreased in the order caffeic acid > sinapic acid > ferulic acid > ferulic acid esters > p-coumaric acid. In bulk methyl linoleate, test hydroxycinnamic acids and ferulic acid esters showed antioxidant activity in parallel with their radical scavenging activity. In an ethanol-buffer solution of linoleic acid, the activity of test compounds was not always associated with their radical scavenging activity. Ferulic acid was most effective among the tested phenolic acids. Esterification of ferulic acid resulted in increasing activity. The activity of alkyl ferulates was somewhat influenced by the chain length of alcohol moiety. When the inhibitory effects of alkyl ferulates against oxidation of liposome induced by AAPH were tested, hexyl, octyl, and 2-ethyl-1-hexyl ferulates were more active than the other alkyl ferulates. Furthermore, lauryl gallate is most effective among the tested alkyl gallates. These results indicated that not only the radical scavenging activity of antioxidants, but also their affinity with lipid substrates, might be important factors in their activity., 2002年03月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 50 (7), 2161 - 2168, doi;web_of_science

    研究論文(学術雑誌)

  • New flavonol-phenylbutadiene adducts from the leaves of Alpinia flabellata

    H Kikuzaki; S Tesaki

    Two new flavonol-phenylbutadiene adducts, rel-5-hydroxy-7,4-dimethoxy-2"S-(2,4,5-trimethoxy-E-styryl)tetrahydrofuro[4"R,5"R:2,3]flavanonol (1) and rel-5-hydroxy-7,4'-dimethoxy-3"S-(2,4,5-trimethoxy-E-styryl)tetrahydrofuro[4"R,5"R:2,3]flavanonol (2), were isolated from the leaves of Alpinia flabellata, along with three known compounds, 2,4,5-trimethoxybenzoic acid, 2,4,5-trimethoxycinnamic acid, and 5-hydroxy-3,7,4'-trimethoxyflavone. The structures of 1 and 2 were determined by spectroscopic interpretation., 2002年03月, JOURNAL OF NATURAL PRODUCTS, 65 (3), 389 - 391, doi;web_of_science

    研究論文(学術雑誌)

  • Antibacterial Activity of Essential Oils and Oleoresins of Spices and Herbs against Pathogens Bacteria in Upper Airway Respiratory Tract

    菊﨑泰枝

    2002年02月, Jpn. J. Food Chem., 9, 67-76

  • Antioxidant Activity of Tropical Plant Leaves Traditionally Used for Food Preservation in Okinawa

    菊﨑泰枝

    2002年01月, ITE Letters on Batteries, New Technologies & Medicine, 3, 63-68

  • Apianane terpenoids from Salvia officinalis

    K Miura; H Kikuzaki; N Nakatani

    Three apianane terpenoids, rel-(5S, 6S, 7S, 10R, 12S, 13R)-7-hydroxyapiana-8,14-diene-11,16-dion-(22,6)-olide, rel-(5S, 6S, 7R, 10R, 12S, 13R)-7-hydroxyapiana-8,14-diene-11,16-dion-(22,6)-olide and rel-(5S, 6S, 7S, 10R, 12R, 13S)-7-hydroxyapiana-8,14diene-11,16-dion-(22,6)-olide were isolated from the leaves of Salvia officinalis, together with 15 known compounds, salvigenin, lupeol, beta -sitosterol, stigmasterol, physcion, carnosol, rosmadial, rosmanol, epirosmanol, isorosmanol, columbaridione, atuntzensin A, miltirone, carnosic acid and 12-O-methyl carnosic acid. Their structures were established on the basis of spectral evidence. (C) 2001 Published by Elsevier Science Ltd., 2001年12月, PHYTOCHEMISTRY, 58 (8), 1171 - 1175, web_of_science

    研究論文(学術雑誌)

  • Antioxidative activity of carbazoles from Murraya koenigii leaves

    Y Tachibana; H Kikuzaki; NH Lajis; N Nakatani

    The antioxidative properties of the leaves extracts of Murraya koenigii using different solvents were evaluated based on the oil stability index (OSI) together with their radical scavenging ability against 1-1-diphenyl-2-picrylhydrazyl (DPPH). The methylene chloride (CH2Cl2) extract and the ethyl acetate (EtOAc) soluble fraction of the 70% acetone extract significantly prolonged the OSI values comparable to those of alpha -tocopherol and BHT. Five carbazole alkaloids were isolated from the CH2Cl2 extract and their structures were identified to be euchrestine B (1), bismurrayafoline E (2), mahanine (3), mahanimbicine (4), and mahanimbine (5) based on H-1 and C-13 NMR and mass (MS) spectral data. The OSI value of carbazoles at 110 degreesC decreased in the order 1 and 3 > alpha -tocopherol > BHT > 2 > 4, 5 and control. It is' assumed that compounds 1 and 3 contributed to the high OSI. value of the CH2Cl2 extract of M. koenigii. The DPPH radical scavenging activity for these carbazoles-was in the order ascorbic acid > 2 > 1, 3 and alpha -tocopherol > BHT > 4 and 5., 2001年11月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 49 (11), 5589 - 5594, doi;web_of_science

    研究論文(学術雑誌)

  • Furanosesquiterpenoids of Commiphora myrrha

    菊﨑泰枝

    2001年11月, J. Nat. Prod., 64, 1460-1462

  • Antibacterial compounds of licorice against upper airway respiratory tract pathogens

    Y Tanaka; H Kikuzaki; S Fukuda; N Nakatani

    The antibacterial activity of compounds obtained from licorice was measured against upper airway respiratory tract bacteria such as Streptococcus pyogenes. Haemophilus influenzae and Moraxella catarrhalis. Among the tested compounds, licoricidin exhibited the highest activity against all tested microorganisms with an MIC of 12.5,mug/mL. Three coumarin derivatives, glycyrol, glycyrin and glycycoumarin also showed antibacterial activity., 2001年06月, JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 47 (3), 270 - 273, web_of_science

    研究論文(学術雑誌)

  • Ecdysteroids of Quinoa seeds (Chenopodium quinoa Willd.)

    N Zhu; H Kikuzaki; BC Vastano; N Nakatani; MV Karwe; RT Rosen; CT Ho

    Quinoa (Chenopodium quinoa) is a hardy and nutritious Latin American pseudo-cereal. Studies on the seeds led to the isolation of five ecdysteroids using column chromatography. Their structures were determined as ecdysterone, makisterone A, 24-epi-makisterone A, 24(28)-dehydromakisterone A. and 20,26-dihydroxyecdysone by spectroscopic methods. This study demonstrates that quinoa seeds are a source of ecdysteroids, which were reported to be molting hormones in insects., 2001年05月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 49 (5), 2576 - 2578, web_of_science

    研究論文(学術雑誌)

  • New constituents of the leaves of Alpinia flabellata

    S Tesaki; H Kikuzaki; S Yonemori; N Nakatani

    As a part of our studies on the constituents of plants belonging to the family Zingiberaceae,(1-5) we have focused on Alpinia flabellata Ridley, which is a rare species in Japan. The leaves of this plant have been used as a wrapping and flavoring material for foods on the islands of Iriomote and Ishigaki, Okinawa, which is the southernmost part of Japan. Only two studies on the isolation of several phenylbutenoids from the rhizomes of A. flabellata have been reported.(6.7) We have reported previously the isolation and structural elucidation of three phenylbutanoid dimers from the leaves of A. flabellatas(8) and now describe the isolation and characterization of a new phenylbutenal (1) and a novel labdane diterpene (2) adducted by a phenylbutenoid., 2001年04月, JOURNAL OF NATURAL PRODUCTS, 64 (4), 515 - 517, web_of_science

    研究論文(学術雑誌)

  • 1,1-diphenyl-2-picrylhydrazyl radical-scavenging active compounds from greater cardamom (Amomum subulatum Roxb.)

    H Kikuzaki; Y Kawai; N Nakatani

    Constituents of the fruits of greater cardamom (Amomum subulatum) were fractionated into three fractions, the dichloromethane extract, and the ethyl acetate-soluble and water-soluble fractions of the 70% aqueous acetone extract, The ethyl acetate-soluble fraction showed a high radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH). Four compounds were isolated from the ethyl acetate-soluble fraction, and their structures were ascribed to protocatechualdehyde (1), protocatechuic acid (2), 1,7-bis(3,4-dihydroxyphenyl)hepta-4E, 6E-dien-3-one (3) and 2,3, 7-trihydroxy-5-(3,4-dihydroxy-E-styryl)-6,7,8,9 -tetrahydro-5H-benzocycloheptene (4) on the basis of spectroscopic evidence. This is the first isolation of these compounds from greater cardamom. In particular, 4 was a new type of cyclic diarylheptanoid. DPPH radical-scavenging activity of these compounds was measured by colorimetric analysis. Compounds 1 and 3 showed stronger activity than such natural antioxidants as alpha -tocopherol and L-ascorbic acid. Compounds 2 and 4 were comparable to alpha -tocopherol and L-ascorbic acid., 2001年04月, JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 47 (2), 167 - 171, web_of_science

    研究論文(学術雑誌)

  • Establishment of a model substrate oil for antioxidant activity assessment by Oil Stability Index method

    N Nakatani; Y Tachibana; H Kikuzaki

    A model substrate oil using methyl linoleate was established for the determination of the antioxidant activity by Oil Stability Index (OSI) method. OSI values for methyl linoleate with different concentrations (5-100%) in silicone oil were measured at different temperatures (70-120 degreesC), As the temperature increased, the OSI value decreased in each concentration of methyl linoleate. Optimal temperature and concentration of methyl linoleate were established. The effect Of concentration of antioxidants, alpha -tocopherol, and butylated hydroxytoluene on OSI values for 10% methyl linoleate model oil was measured at 90, 100, 110, and 120 degreesC, The logarithmic reiationship between temperature and OSI using model substrate oil was similar to that of soybean oil. Furthermore, application of some spice extracts to this model oil system was carried out to give results that compared well with those available in the literature. Thus, the procedure using methyl linoleate-silicone oil as a model substrate oil is available for evaluating the antioxidant activity by the OSI method., 2001年01月, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 78 (1), 19 - 23, web_of_science

    研究論文(学術雑誌)

  • Phenylbutanoid dimers from the leaves of Alpinia flabellata

    H Kikuzaki; S Tesaki; S Yonemori; N Nakatani

    Three phenylbutanoid dimers, cis- and trans-1-(2,4,5-trimethoxy-E-styryl)-2-(2,4,5-trimethoxy-Z-styryl)cyclobutane and 1,2- bis(2,4,5-trimethoxy-Z-styryl)- cyclobutane, were isolated from the leaves of Alpinia flabellata Ridley, together with three known compounds (2,4,5-trimethoxybenzaldehyde, 2,4,5-trimethoxycinnamaldehyde and 3,5-dihydroxy-7,4'-dimethoxyflavone). The structures of these compounds were determined by spectroscopic analysis. (C) 2001 Elsevier Science Ltd. All rights reserved., 2001年01月, PHYTOCHEMISTRY, 56 (1), 109 - 114, web_of_science

    研究論文(学術雑誌)

  • Antibacterial Activity of Phenolic Constituents Isolated from Alpinia flabellata and Their Regulating Effect on Ovalbumin Transport in Human Intestinal Caco-2 Cells

    菊﨑泰枝

    2001年01月, ITE Letters on Batteries, New Technologies & Medicine, 2, 106-111

  • Identification, quantitative determination, and antioxidative activities of chlorogenic acid isomers in prune (Prunus domestica L.)

    N Nakatani; S Kayano; H Kikuzaki; K Sumino; K Katagiri; T Mitani

    Neochlorogenic acid (3-CQA) and cryptochlorogenic acid (4-CQA), isolated from prune (Prunus domestica L.), were identified by NMR and MS analyses. In addition, the quantity of chlorogenic acid isomers in prune were measured by HPLC. These isomers, 3-CQA, 4-CQA, and chlorogenic acid (5-CQA), were contained in the ratio 78.7:18.4:3.9, respectively. 4-CQA was identified and quantified in prune for the first time, and relatively high amounts of this isomer were characteristic. Antioxidative activities of the chlorogenic acid isomers, such as scavenging activity on superoxide anion radicals and inhibitory effect against oxidation of methyl linoleate, were also evaluated. Each isomer showed antioxidative activities which were almost the same., 2000年11月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 48 (11), 5512 - 5516, doi;web_of_science

    研究論文(学術雑誌)

  • Antibacterial Activity of Aliphatic Long Chain Compounds against Upper Airway Respiratory Tract Bacteria

    菊﨑泰枝

    2000年09月, ITE Letters on Batteries, New Technologies & Medicine, 1, 777-780

  • アガリクス(Agaricus blazei)子実体の抗酸化成分および多糖の研究

    菊﨑泰枝; 角田万里子; 谷川晶子; 菊崎泰枝; 三崎旭

    2000年09月, 微量栄養素研究, 17, 83-90

  • Chemopreventive effects of coumaperine from pepper on the initiation stage of chemical hepatocarcinogenesis in the rat

    M Kitano; H Wanibuchi; H Kikuzaki; N Nakatani; S Imaoka; K Funae; S Hayashi; S Fukushima

    This study was designed to investigate the chemopreventive action of three natural products, coumaperine, aurapten and an extract from rosemary, against the initiation stage of rat hepatocarcinogenesis. Coumaperine has been isolated from white pepper as a naturally occurring antioxidative agent, but its potential modifying effects on carcinogenesis remain unclear. In experiment 1, a modification of the model developed by Tsuda et al. was applied, with assessment of numbers and areas of induced glutathione S-transferase placental form (GST-P)-positive hepatocellular foci in male F344 rats. Coumaperine, aurapten and the extract from rosemary were administered i.g. at 190 mg/kg/day once daily for 5 days with initiation by diethylnitrosamine (DEN) on day 4 (20 mg/kg, i.p.). Numbers and areas of GST-P-positive foci in each group given test chemicals tended to be decreased as compared to the vehicle control group values, significance being achieved for number with coumaperine. Experiment 2 was planned to investigate the mechanism of the inhibitory effects of coumaperine. Livers at 8 h after initiation by DEN were examined with coumaperine administered at 100 mg/kg/day once daily for 3 days. Proliferating cell nuclear antigen (PCNA)positive cells tended to be decreased as compared to the vehicle control, but no effects on apoptosis or cytochrome P-450 (CYP) 2E1 expression were apparent. Our results suggest that coumaperine provides protection against initiation of hepatocarcinogenesis, and that this is related to inhibition of cell proliferation., 2000年07月, JAPANESE JOURNAL OF CANCER RESEARCH, 91 (7), 674 - 680, web_of_science

    研究論文(学術雑誌)

  • Novel glycosides from noni (Morinda citrifolia)

    Mingfu Wang; Hiroe Kikuzaki; Yi Jin; Nobuji Nakatani; Nanqun Zhu; Katalin Csiszar; Charles Boyd; Robert T. Rosen; Geetha Ghai; Chi-Tang Ho

    Three new glycosides were isolated from the fruits of noni (Morinda citrifolia). Their structures were determined to be 6-O-(β-D-glucopyranosyl)-1-O-octanoyl-β-D-glucopyranose (1), 6-O-(β-D-glucopyranosyl)-1-O-hexanoyl-β-D-glucopyranose (2), and 3-methylbut-3-enyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside (3) using MS and NMR methods., 2000年, Journal of Natural Products, 63 (8), 1182 - 1183, doi;pubmed

    研究論文(学術雑誌)

  • Constituents of Amomum tsao-ko and their radical scavenging and antioxidant activities

    TS Martin; H Kikuzaki; M Hisamoto; N Nakatani

    Constituents of the fruit of Amomum tsao-ko were investigated following a preliminary screening of the antioxidant activity of several extracts of the fruit of this plant that showed that the dichloromethane extract and the ethyl acetate-soluble and water-soluble fractions of the 70% aqueous acetone extract had higher activity than alpha-tocopherol and butylated hydroxytoluene (BHT). Eleven compounds were isolated from the ethyl acetate-soluble fraction, and their structures were elucidated as (+)-hannokinol (1), meso-hannokinol (2), (+)-epicatechin (3), (-)-catechin (4), beta-sitosterol (5), beta-sitosterol 3-O-glucoside (6), 2,6-dimethoxyphenol (7), protocatechualdehyde (8), protocatechuic acid (9), vanillic acid (10), and beta-hydroxybenzoic acid (11) based on mass and various nuclear magnetic resonance (NMR) spectroscopic techniques. This is the first isolation of epicatechin and catechin from the genus Amomum. The radical scavenging activity of the isolated compounds was evaluated using 1,1-diphenyl-2-picryIhydrazyl (DPPH) and colorimetric and electron spin resonance (ESR) analyses. The antioxidant activity of the compounds was also determined based on the oxidative stability index (OSI). The catechins and catechol derivatives showed strong activities in both the DPPH radical scavenging activity and antioxidant activity assays., 2000年06月, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 77 (6), 667 - 673, web_of_science

    研究論文(学術雑誌)

  • Antibacterial Compounds from Nutmeg against Upper Airway Respiratory Tract Bacteria

    菊﨑泰枝

    2000年05月, ITE Letters on Batteries, New Technologies & Medicine,, 1, 412-417

  • Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)

    MF Wang; H Kikuzaki; NQ Zhu; SM Sang; N Nakatani; CT Ho

    Six compounds, 1-O-(2,3,4-trihydroxy-3-methyl)butyl-6-O-feruloyl-beta-D-glucopyranoside, ethyl beta-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-beta-D-apiofrunosyl]-(1-->2)-beta-D-glucopyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and BD-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound., 2000年02月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 48 (2), 235 - 238, web_of_science

    研究論文(学術雑誌)

  • Screening of Zingiberaceae Extracts for Antimicrobial and Antioxidant Activities

    菊﨑泰枝

    2000年02月, Journal of Ethnopharmacology, 72, 403-410

  • Galloylglucosides from Berries of Pimenta dioica

    菊﨑泰枝

    2000年01月, J. Nat. Prod, 63, 749-752

  • Antioxidative phenylpropanoids from berries of Pimenta dioica

    H Kikuzaki; S Hara; Y Kawai; N Nakatani

    A phenylpropanoid, threo-3-chloro-1-(4-hydroxy-3-methoxy phenyl)propane-1,2-diol, was isolated from the berries of Pimenta dioica together with five known compounds. eugenol, 4-hydroxy-3-methoxycinnamaldehyde, 3,4-dimethoxycinnamaldehyde, vanillin and 3-(4-hydroxy-3-methoxyphenyl)propane-1,2-diol. In addition, the stereochemistry of 3-(4-hydroxy-3-methoxyphenyl)propane- 1,2-diol was determined. The phenylpropanoids inhibited autoxidation of linoleic acid in a water-alcohol system. (C) 1999 Elsevier Science Ltd. All rights reserved., 1999年12月, PHYTOCHEMISTRY, 52 (7), 1307 - 1312, web_of_science

    研究論文(学術雑誌)

  • Two C-21-steroidal glycosides isolated from Cynanchum stauntoi

    NQ Zhu; MF Wang; H Kikuzaki; N Nakatani; CT Ho

    Studies on the roots of Cynanchum stauntoi led to the isolation of two C-21-steroidal glycosides, formally named stauntosides A and B. Their structures were elucidated on the basis of spectroscopic evidence, especially that from analysis of 2D-NMR spectra. They were found to possess an unusual skeleton and were identified as stauntogenin 3-O-alpha-L-diginopyranosyl-(1-4)beta-L-cymaropyranosyl-(1-4)-beta-D-digitoxopyranosyl-(1-4)-beta-D-thevetopyranoside and stauntogenin 3-O-alpha-L-cymaropyranosyl-(1-4)-beta-D-digitoxopyranosyl-(1-4)-beta-D-3-demethyl-2-deoxy-thevetopyranoside (C) 1999 Elsevier Science Ltd. All rights reserved., 1999年12月, PHYTOCHEMISTRY, 52 (7), 1351 - 1355, web_of_science

    研究論文(学術雑誌)

  • Novel trisaccharide fatty acid ester identified from the fruits of Morinda citrifolia (Noni)

    MF Wang; H Kikuzaki; K Csiszar; CD Boyd; A Maunakea; SFT Fong; G Ghai; RT Rosen; N Nakatani; CT Ho

    Two known glycosides and a novel trisaccharide fatty acid ester were isolated from the n-butanol-soluble fraction of the fruits of Morinda citrifolia (noni). Structure determination was carried out by spectral techniques such as MS, IR, NMR, and BD-NMR. The novel trisaccharide fatty acid ester was elucidated as 2,6-di-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-glucopyranose. The known compounds were identified as rutin and asperulosidic acid., 1999年12月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 47 (12), 4880 - 4882, web_of_science

    研究論文(学術雑誌)

  • 二倍体および四倍体ショウガの辛味成分と官能検査による辛味性評価ならびにメタノール抽出物の抗酸化性

    菊﨑泰枝; 仲宗根洋子; 与那覇恵; 和田浩二; 安谷屋信一; 菊崎泰枝; 中谷延二

    1999年06月, 熱帯農業, 43, 71-75

  • Antioxidant Effect of the Constituents of Susabinori (Porphyra yezoensis)”

    菊﨑泰枝

    The antioxidant activities of several extracts from Susabinori (Porphyra yezoensis) were measured by the ferric thiocyanate method and the thiobarbituric acid method. The methanol, acetone, ethyl acetate, and hexane extracts, and the chloroform-soluble and water-soluble fractions from the chloroform-methanol extract exhibited higher activities than a-tocopherol. The hot water extract showed little activity. Thin-layer chromatography analysis of the active extracts suggested the existence of several antioxidants. The activity of the chloroform soluble fraction was due to chlorophyll analogs. A strong antioxidant was isolated from the methanol extract, accompanied by several amino acids such as leucine and phenylalanine. This compound was identified as usujilene, a kind of mycosporine-glycine like amino acid., 1999年05月, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 76 (5), 649 - 653, web_of_science

    研究論文(学術雑誌)

  • Acetophenone glycosides from thyme (Thymus vulgaris L.)

    MF Wang; H Kikuzaki; CC Lin; A Kahyaoglu; MT Huang; N Nakatani; CT Ho

    Four acetophenone glycosides were isolated from the butanol-soluble fraction of thyme extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR). Among them, two new compounds, 4-hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-beta-D-apiofuranosyl]-(1-->2)-beta-D-glucopyranoside (1) and 4-hydroxyacetophenone 4-O-[5-O-(4-hydroxybenzoyl)-beta-D-apiofuranosyl]-(1-->2)-beta-D-glucopyranoside (2), were determined. Compound 1 showed weak cytotoxicity, inhibiting DNA synthesis of human leukemia cells., 1999年05月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 47 (5), 1911 - 1914, web_of_science

    研究論文(学術雑誌)

  • New bitter diterpenes, rabdosianone I and II, isolated from Isodon japonicus Hara

    Y Yamada; N Sako; E Ando; M Yamada; H Kikuzaki; T Yamamoto

    The new bitter diterpenes, rabdosianone I(C20H24O5) and II (C22H28O6), were isolated from Isodon japonicus (Japanese name, enmeiso), and their structures were elucidated by spectroscopic methods, Electrophysiological experiments were performed to compare rabdosianone I with quinine. The taste responses of chorda tympani nerves to rabdosianone I were smaller than those to quinine in Wistar rats., 1999年03月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 63 (3), 524 - 529, web_of_science

    研究論文(学術雑誌)

  • Spasmolytic activity of aurapten analogs

    Y Yamada; M Okamoto; H Kikuzaki; N Nakatani

    Seven coumaric compounds analogous to aurapten were synthesized. Their spasmolytic activity against Ba2+, acetylcholine and histamine was evaluated to investigate their structure-activity relationship. The results of the bioassay demonstrated the important roles of the cis type of double bond at C-2' and the epoxide between C-6' and 7'., 1997年04月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 61 (4), 740 - 742, web_of_science

    研究論文(学術雑誌)

  • Antioxidative Activity of Constituents from Fennel Seeds

    菊﨑泰枝

    1996年12月, J. Home Econ. Jpn., 47, 1193-1199

  • 延命草(Isodon japonicus) に含まれる新規な苦味化合物の構造

    菊﨑泰枝; 山田恭正; 硲 哲崇; n 安藤えり子; 菊崎泰枝; 山本 隆

    1996年12月, 日本味と匂学会誌, 3, 584-587

  • Stability of anthocyanins of Sambucus canadensis and Sambucus nigra

    O Inami; Tamura, I; H Kikuzaki; N Nakatani

    Elderberry anthocyanins (Sambucus nigra) including acylated derivatives (Sambucus canadensis) were studied for use as beverage pigments. Cyanidin 3-O-(6-O-E-p-coumaroyl-2-O-beta-D-xylopyranosyl)-beta-D-glucopyranoside-5-O-beta-D-glucopyranoside from S. canadensis was more stable than cyanidin 3-sambubioside from S. nigra. Acylation improved both heat and light stability, whereas glycosidation only stabilized anthocyanins in the presence of light. Cyanidin 3-(E)-p-coumaroyl-sambubioside-5-glucoside changed to three new anthocyanins under light irradiation. These three anthocyanins were isolated, and their structures were identified to be cyanidin 3-O-(6-O-Z-p-coumaroyl-2-O-beta-D-xylopyranosyl)-beta-D-glucopyranoside-5-O-beta-D-glucopyranoside, cyanidin 3-O-(6-O-E-p-coumaroyl-2-O-beta-D-xylopyranosyl)-beta-D-glucopyranoside, and cyanidin 3-O-(6-O-Z-p-coumaroyl-2-O-beta-D-xylopyranosyl)-beta-D-glucopyranoside., 1996年10月, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 44 (10), 3090 - 3096, web_of_science

    研究論文(学術雑誌)

  • Cyclic diarylheptanoids from rhizomes of Zingiber officinale

    H Kikuzaki; N Nakatani

    Five new diarylheptanoids were isolated from the rhizomes of Zingiber officinale and their structures elucidated by spectroscopic and chemical methods. They were oxygenated at C-1, 3 and 5 on the heptane chain and cyclized between C-1 and C-5 through oxygen. Copyright (C) Elsevier Science Ltd, 1996年09月, PHYTOCHEMISTRY, 43 (1), 273 - 277, web_of_science

    研究論文(学術雑誌)

  • Secoiridoid glucosides from Swertia mileensis

    Hiroe Kikuzaki; Yoko Kawasaki; Seiichi Kitamura; Nobuji Nakatani

    Five new acyl secoiridoid glucosides along with three known secoiridoid glucosides, swertiamarin, 2'-O-acetylswertiamarin, and amarogentin, were isolated from the aerial parts of Swertia mileensis. The structures of these compounds were determined to be 2'-O-acetyl-4'-O-trans-feruloylswertiamarin, 2'-O-acetyl-4'-O-cis-feruloylswertiamarin, 2'-O-acetyl-4'-O-trans-p-coumaroylswertiamarin, 2'-O-acetyl-4'-O-cis-p-coumaroylswertiamarin, and 4'-O-trans-p-coumaroylswertiamarin from spectroscopic evidence., 1996年, Planta Medica, 62 (1), 35 - 38, doi;pubmed

    研究論文(学術雑誌)

  • Acylated anthocyanins from fruits of Sambucus canadensis

    Nobuji Nakatani; Hiroe Kikuzaki; Junko Hikida; Mayumi Ohba; Osamu Inami; Itaru Tamura

    Two new acylated anthocyanin glycosides were isolated from fruits of Sambucus canadensis. The structures were determined to be cyanidin 3-O-(6-O-Z-p-coumaroyl-2-O-β-d-xylopyranosyl)-β-d-glucopyranoside)-5-O-β-d-glucopyranoside and cyanidin 3-O-(6-O-E-p-coumaroyl-2-O-β-d-xylopyranosyl)-β-d-glucopyranoside. © 1995., 1995年, Phytochemistry, 38 (3), 755 - 757, doi;pubmed

    研究論文(学術雑誌)

  • LABDANE DITERPENES FROM RHIZOMES OF HEDYCHIUM-CORONARIUM

    N NAKATANI; H KIKUZAKI; H YAMAJI; K YOSHIO; C KITORA; K OKADA; WG PADOLINA

    Three new labdane diterpenes were isolated together with four known diterpenes [(E)-labda-8(17),12-diene-15,16-dial, coronarin B and D, and isocoronarin D] from rhizomes of Hedychium coronarium. The structures of the new compounds were determined by spectroscopic evidence to be labda-8(17),11,13-trien-15(16)-olide, an ester of labda-8(17), 11,13-trien-15-al-16-oic acid and isocoronarin D, and 7 beta-hydroxycoronarin B., 1994年11月, PHYTOCHEMISTRY, 37 (5), 1383 - 1388, web_of_science

    研究論文(学術雑誌)

  • TRANSFORMATION OF GLYCYRRHIZIC ACID BY ASPERGILLUS SPP

    Y YAMADA; A NAKAMURA; K YAMAMOTO; H KIKUZAKI

    Glycryrrhizic acid was metabolized to 3-oxo-18 beta-glycyrrhetinic acid via 18 beta-glycyrrhetinic acid by Aspergillus niger, A. oryzae, A. sojae, and A. tamarii. Two methyl esters were derived from these two metabolites and identified by their C-13-NMR spectra and MS data., 1994年02月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 58 (2), 436 - 437, web_of_science

  • STRUCTURE OF ANTIOXIDATIVE COMPOUNDS IN GINGER

    H KIKUZAKI; Y KAWASAKI; N NAKATANI

    Fourteen gingerol related compounds and seven diarylheptanoids were isolated from ginger rhizomes. Their structures were elucidated on the basis of chemical and spectroscopic evidence. Most of the isolated compounds exhibited stronger antioxidative effect than alpha-tocopherol. The antioxidant activity depended upon substituents on the side chain and benzene ring, and the length of side chain., 1994年, FOOD PHYTOCHEMICALS FOR CANCER PREVENTION II, 547, 237 - 243, web_of_science

    研究論文(学術雑誌)

  • LC-MS ANALYSIS AND STRUCTURAL DETERMINATION OF NEW AMIDES FROM JAVANESE LONG PEPPER (PIPER-RETROFRACTUM)

    H KIKUZAKI; M KAWABATA; E ISHIDA; Y AKAZAWA; Y TAKEI; N NAKATANI

    Amides in a CH2Cl2 extract from the fruits of Piper retrofractum were detected by HPLC/APCI-MS. Seven new unsaturated amides, together with six known ones, were isolated, and their structures were determined to be N-isobutyl-2E,4E,12Z-octadecatrienamide (1), N-isobutyl-2E,4E,14Z-eicosatrienamide (2), 1-(octadeca-2E,4E,12Z-trienoyl)piperidine (3), 1-(eicosa-2E,4E,14Z-trienoyl)piperidine (4), 1-(octadeca-2E,4E-dienoyl)piperidine (5), 1-(eicosa-2E,4E-dienoyl)piperidine (6), and 1-(eicosa-2E,14Z-dienoyl)piperidine (7) on the basis of chemical and spectroscopic evidence., 1993年08月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 57 (8), 1329 - 1333, web_of_science

    研究論文(学術雑誌)

  • Antioxidant Effects of Some Ginger Constituents

    HIROE KIKUZAKI; NOBUJI NAKATANI

    The nonvolatile fraction of the dichloromethane extract of ginger rhizomes exhibited a strong antioxidative activity using linoleic acid as the substrate in ethanol‐phosphate buffer solution. The fraction was purified by chromatographic techniques to provide five gingerol related compounds and eight diarylheptanoids. Among them, 12 compounds exhibited higher activity than α‐tocopherol. The activity was probably dependent upon side chain structures and substitution patterns on the benzene ring. Copyright © 1993, Wiley Blackwell. All rights reserved, 1993年, Journal of Food Science, 58 (6), 1407 - 1410, doi

    研究論文(学術雑誌)

  • 2 CURCUMINOID PIGMENTS FROM CURCUMA-DOMESTICA

    R NAKAYAMA; Y TAMURA; H YAMANAKA; H KIKUZAKI; N NAKATANI

    Two new pigments were isolated from fresh rhizomes of turmeric (Curcuma domestica Val.). Their structures were determined to be 1-(4-hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)-1,6-heptadiene-3,5-dione and 1,7-bis (4-hydroxyphenyl)-1,4,6-heptatrien-3-one by spectroscopic methods., 1993年05月, PHYTOCHEMISTRY, 33 (2), 501 - 502, web_of_science

  • Identification of Antimicrobial Gingerols from Ginger (Zingiber officinale Roscoe)

    菊﨑泰枝

    1992年06月, J. Antibact. Antifung. Agents, 20, 309-311

  • CHARACTERIZATION OF HIGH-AMYLOSE TYPE ENDOSPERM STARCHES OF RICE PLANTS CULTIVATED IN ASIA

    H FUWA; K OKUNO; R ASASHIBA; H KIKUZAKI; M ASAOKA; N INOUCHI; Y SUGIMOTO

    Starch granules were prepared from 14 indica rice grains which were collected from various places of Asia and had the amylose content of 28% and over by a blue value method. The starches were high- and medium-amylose types by the enzymatic and chromatographic method. However, none of them belonged to the type of high amylose mutants which were induced by the chemical mutagen treatment of a japonica rice cultivar: Kinmaze and possessed similar characteristics of endosperm starch to that of the amylose-extender (ae) mutant of maize (Zea mays L.)., 1992年06月, STARCH-STARKE, 44 (6), 203 - 205, web_of_science

    研究論文(学術雑誌)

  • CONSTITUENTS OF ZINGIBERACEAE .5. GINGERDIOL RELATED-COMPOUNDS FROM THE RHIZOMES OF ZINGIBER-OFFICINALE

    H KIKUZAKI; SM TSAI; N NAKATANI

    [6]-Gingerdiol and four analogues, (3R,5S)-5-acetoxy-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decane, (3R,5S)-3-acetoxy-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decane,(3R,5S)-3,5-diacetoxy-1-(4-hydroxy-3-methoxyphenyl)decane and (3R,5S)-3,5-diacetoxy-1-(3,4-dimethoxyphenyl)decane, were isolated from the rhizomes of Zingiber officinale. Their structures were established by chemical and spectroscopic evidence., 1992年05月, PHYTOCHEMISTRY, 31 (5), 1783 - 1786, web_of_science

    研究論文(学術雑誌)

  • New Phenolic Compounds of Ginger (Zingiber officinale Roscoe)

    菊﨑泰枝

    1992年03月, Chemistry Express, 7, 221-224

  • Microbial Transformation of (±)- Epoxyaurapten by Pseudomonas aeruginosa

    菊﨑泰枝

    1992年01月, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 56 (1), 153 - 154, web_of_science

  • Constituents of Gyrophora esculenta

    菊﨑泰枝

    1991年08月, Chemistry Express, 6, 587-590

  • CONSTITUENTS OF ZINGIBERACEAE .1. DIARYLHEPTANOIDS FROM THE RHIZOMES OF GINGER (ZINGIBER-OFFICINALE ROSCOE)

    H KIKUZAKI; J USUGUCHI; N NAKATANI

    Two new diarylheptanoids, meso-3,5-diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane (3a) and 3,5-diacetoxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane (4a) were isolated from the rhizomes of ginger (Zingiber officinale ROSCOE), together with dehydroxytetrahydrocurcumin (gingerenone A, 1) and hexahydrocurcumin (2). Their structures were elucidated on the basis of chemical and spectroscopic evidence., 1991年01月, CHEMICAL & PHARMACEUTICAL BULLETIN, 39 (1), 120 - 122, web_of_science

    研究論文(学術雑誌)

  • CONSTITUENTS OF PIPERACEAE .4. ANTIMICROBIAL PHENYLPROPANOIDS FROM PIPER-SARMENTOSUM

    T MASUDA; A INAZUMI; Y YAMADA; WG PADOLINA; H KIKUZAKI; N NAKATANI

    One new and three known phenylpropanoids have been isolated from the leaves of Piper sarmentosum. They are 1-allyl-2,6-dimethoxy-3,4-methylenedioxybenzene, 1-allyl-2,4,5-trimethoxybenzene, 1-(1-E-propenyl)-2,4,5-trimethoxybenzene and 1-allyl-2-methoxy-4,5-methylenedioxybenzene. The new compound showed antimicrobial activity against Escherichia coli and Bacillus subtilis., 1991年, PHYTOCHEMISTRY, 30 (10), 3227 - 3228, web_of_science

    研究論文(学術雑誌)

  • CONSTITUENTS OF ZINGIBERACEAE .4. DIARYLHEPTANOIDS FROM RHIZOMES OF ZINGIBER-OFFICINALE

    H KIKUZAKI; M KOBAYASHI; N NAKATANI

    Six new diarylheptanoids, 5-hydroxy-7-(4-hydroxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)-3-heptanone, 3,5-diacetoxy-7-(3,4-dihydroxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)heptane, 5-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-3-heptanone, 5-hydroxy-7-(4-hydroxy-3,5-dimethoxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)-3-heptanone, (3R,5S)-3,5-dihydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane and (3S,5S)-3,5-diacetoxy-1,7-bis(3,4-dihydroxyphenyl)heptane were isolated from the rhizomes of Zingiber officinale, together with two known diarylheptanoids. Their structures were established by chemical and spectroscopic evidences., 1991年, PHYTOCHEMISTRY, 30 (11), 3647 - 3651, web_of_science

    研究論文(学術雑誌)

  • Synthesis of Capsaicinol [1]

    菊﨑泰枝

    1990年06月, Chemistry Express, 5, 369-372

  • STRUCTURE OF A NEW ANTIOXIDATIVE PHENOLIC-ACID FROM OREGANO (ORIGANUM-VULGARE L)

    H KIKUZAKI; N NAKATANI

    1989年02月, AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 53 (2), 519 - 524, web_of_science

    研究論文(学術雑誌)

  • Antioxidative Compounds from Edible Plants: Phenolic Amides from Capsicum frutescens L.

    菊﨑泰枝

    1989年, Medical, Biochemical and Chemical Aspects of Free Radicals, 453-456

  • LIGNANS OF PAPUAN MACE (MYRISTICA-ARGENTEA WARB) .2. DIARYLDIMETHYLBUTANE LIGNANS FROM MYRISTICA-ARGENTEA AND THEIR ANTIMICROBIAL ACTION AGAINST STREPTOCOCCUS MUTANS

    N NAKATANI; K IKEDA; H KIKUZAKI; M KIDO; Y YAMAGUCHI

    1988年, PHYTOCHEMISTRY, 27 (10), 3127 - 3129, web_of_science

    研究論文(学術雑誌)

  • A NEW ANTIOXIDATIVE GLUCOSIDE ISOLATED FROM OREGANO (ORIGANUM-VULGARE L)

    N NAKATANI; H KIKUZAKI

    1987年10月, AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 51 (10), 2727 - 2732, web_of_science

    研究論文(学術雑誌)

  • Structure of Diacylated Anthocyanins from Red Cabbage (Brassica oleracea)

    菊﨑泰枝

    1987年09月, Chemistry Express, 2, 555-558

  • Structure of Two Acylated Anthocyanins from Red Cabbage (Brassica oleracea)

    菊﨑泰枝

    1987年09月, Chemistry Express, 2, 563-366

  • 大豆油の消化管内移動におよぼすペクチンの影響

    菊﨑泰枝; 片山(須川)洋子; 菊崎泰枝; 泉田明子

    1987年01月, 日本栄養・食糧学会誌, 40, 64-69

  • Isolation of phenolic components from strawberry cultivar 'Tokun' and their inhibitory activities on recombinant human histidine decarboxylase

    Yoko Nitta; Miyuki Mori; Yuji Noguchi; Yuichi Uno; Misaki Ishibashi; Hiroshi Ueno; Hiroe Kikuzaki

    2020年08月, J. Biol. Macromol., 20 (2), 33 - 39

    研究論文(学術雑誌)

  • The ellagitannin trimer rugosin G inhibits recombinant human histidine decarboxylase.

    Yoko Nitta; Hideyuki Ito; Hirohumi Komori; Hiroshi Ueno; Daiki Takeshima; Mikiko Ito; Motoyoshi Sakaue; Hiroe Kikuzaki

    Rugosin G, an ellagitannin trimer, was isolated from the water-soluble fraction of red rose petals, and its inhibitory activity against recombinant human histidine decarboxylase was investigated. Rugosin G showed potent inhibition compared to ellagitannin monomers and a dimer with macrocyclic structure (oenothein B), suggesting the potent inhibition of rugosin G was attributed to its linear oligomeric conformation. Abbreviations: HDC, histidine decarboxylase; Me2CO, acetone; EtOAc, ethyl acetate., 2019年07月, Bioscience, biotechnology, and biochemistry, 83 (7), 1315 - 1318, 国際誌, doi;pubmed

    研究論文(学術雑誌)

  • Components for Inhibiting Lipid Oxidation Related to Discoloration of Carotenoid Contained in Sugarcane Extract

    Hiroe Kikuzaki; Mihoko Masuda; Eri Kishi; Mina Ozaki; Kanako Kondo; Aya Kanai; Kazuyo Shiomi; Toma Furuta; Masami Mizu; Yukie Nagai

    2019年, Food Science and Technology Research, 25 (5), 715 - 725, doi;url

    研究論文(学術雑誌)

  • Biological Activities of Isolated Compounds from Three Edible Malaysian Red Seaweeds, Gracilaria changii, G. manilaensis and Gracilaria sp.

    Yosie Andriani; Desy Fitrya Syamsumir; Tee Ching Yee; Faizah Shaharom Harisson; Gan Ming Herng; Siti Aishah Abdullah Christine Abellana Oroscoa; Christine Abellana Orosco; Abdul Manaf Ali; Jalifah Latip; Hiroe Kikuzaki; Habsah Mohamad

    Gracilaria species are red marine macroalgae that are found abundantly in Malaysia. Gracilaria changii from Morib, Selangor, G. manilaensis and Gracilaria sp. from Gelang Patah, Johor were used in this study. Five compounds were successfully isolated and identified as hexadecanoic acid (1), cholest-5-en-3-ol (2), 2-hydroxymyristic acid (3), cholesteryl myristate (4) and 1-(4'-methoxyphenyl)-3-(2 '',4 '',6 ''-trihydroxyphenyl)-3-hydroxypropanone (5) based on spectral data analysis (IR, UV, GC-MS, H-1 NMR, C-13 NMR, HMQC and HMBC). All compounds isolated were tested for cytotoxicity (MTT assay for HL-60 and MCF-7 cell lines), and antibacterial (disc diffusion method), antioxidant (DPPH free radical scavenging assay and xanthine oxidase inhibitory assay) and acetylcholinesterase inhibitory (AChE) activity (TLC bioautographic method). Compounds 1 and 3 exhibited strong cytotoxic activity against HL-60 and MCF-7 cell lines. Compound 5 showed high antioxidant activity in both the DPPH free radical scavenging and xanthine oxidase inhibition assays. Compound 1 showed positive activity for AChE inhibitory with a minimum inhibition dose of 0.625 mu g sample. All compounds demonstrated antibacterial activity producing 8 to 14 mm inhibition zones. A positive control was applied to all bioassays and experiments were performed with three replicates. Results demonstrated that three edible red seaweeds are rich sources of bioactive compounds with potential application for pharmaceutical purposes., 2016年08月, NATURAL PRODUCT COMMUNICATIONS, 11 (8), 1117 - 1120, web_of_science

    研究論文(学術雑誌)

  • Antioxidants from some tropical spices

    H Kikuzaki

    2003年, ORIENTAL FOODS AND HERBS, 859, 176 - 189, web_of_science

    研究論文(学術雑誌)

MISC

  • 薬用植物を使用したアレルギー様食中毒予防の研究

    北隆館, 2020年12月30日, アレルギーの臨床, 40 (14), 50 - 52

  • 質量分析から得られる食品成分情報を活用した最近の研究

    三栄源エフ・エフ・アイ株式会社, 2020年/1月, Food & Food Ingredients Journal of Japan, 225 (4), 339 - 345

  • フトモモ科スパイス(クローブ,オールスパイス)の食文化と機能性

    菊﨑泰枝

    2017年12月, Functional Food, 11 (2), 111-116

  • ショウガの食文化と機能性

    菊﨑泰枝

    2017年12月, Functional Food, 11 (2), 122-128

  • ショウガ科香辛料の特徴的成分~その機能性~

    菊﨑泰枝

    2017年08月, AROMA RESEARCH, 18 (3), 42-47

  • ガロタンニン,エラジタンニンによるヒスチジン脱炭酸酵素の活性阻害の解析

    森美幸; 菊崎泰枝; 植野洋志; 小森博文; 新田陽子

    2016年04月25日, ビタミン, 90 (4), 184, j_global;url

  • ローズペタル成分によるヒト由来ヒスチジン脱炭酸酵素の阻害

    森美幸; 渡邉裕香; 新田陽子; 植野洋志; 秋本梢; 小林慧子; 菊崎泰枝

    2015年09月01日, 生物高分子, 15 (1), 74, j_global;url

  • メドウスイート抽出液によるサバのヒスタミン汚染抑制

    安方芙実子; 北元憲利; 新田陽子; 江戸良也子; 植野洋志; 菊崎泰枝

    2015年09月01日, 生物高分子, 15 (1), 74, j_global;url

  • Rosa gallicaの花弁に含まれるヒスチジン脱炭酸酵素阻害成分の探索

    秋本梢; 渡邉裕香; 新田陽子; 植野洋志; 小林慧子; 菊崎泰枝

    2014年03月05日, 日本農芸化学会大会講演要旨集(Web), 2014, 4B04A08 (WEB ONLY), j_global;url

  • ヒスタミン合成を阻害する薬用植物成分の探索

    胡榴; 新田陽子; 菊崎泰枝; 植野洋志

    2008年10月01日, 生物高分子, 8 (3), 87, j_global;url

  • Antimicrobial Activity of Saponins from Leaves of Bacopa monnieri

    Masashi Hisamoto; Naomi Nishihara; Tohru Okuda,Huong Lai Mai; Hiroe Kikuzaki; Koki Yokotsuka; Koki Yokotsuka

    2008年, Journal of Clinical Biochemistry and Nutrition, 43, 1 - 3

  • ヒト由来ヒスチジンデカルボキシラーゼの活性を阻害する香辛料成分

    新田陽子; 菊崎泰枝; 植野洋志

    2008年, 日本農芸化学会関西支部講演会講演要旨集, 455th, 16, j_global;url

  • ショウガ科植物の化学成分

    菊﨑泰枝

    2007年03月, 香料, 233, 81-87

  • ヒスチジン脱炭酸酵素の活性を阻害する食品成分

    新田陽子; 菊崎泰枝; 植野洋志

    2006年07月01日, 生物高分子, 6 (2), 57, j_global;url

  • オールスパイス(ピメント)の抗酸化成分の解明

    菊﨑泰枝

    2002年10月, 香料, 215, 101-106

  • 沖縄の伝統的食用植物の機能性

    菊﨑泰枝

    2001年07月, FOOD Style 21, 5 (7), 50-53

  • Antioxidants in the ginger family.

    N Nakatani; H Kikuzaki

    AMER CHEMICAL SOC, 2000年08月, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 220, U42 - U42, web_of_science

    研究発表ペーパー・要旨(国際会議)

  • ANTIOXIDANT ACTIVITY OF POLYPHENOLS IN FOOD

    N NAKATANI; H KIKUZAKI

    JAPAN SOC BIOSCI BIOTECHN AGROCHEM, 1995年09月, NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 69 (9), 1189 - 1192, web_of_science

    書評論文,書評,文献紹介等

  • 食品中のポリフェノールの抗酸化活性

    菊﨑泰枝; 中谷延二; 菊崎泰枝

    1995年09月, 日本農芸化学会誌, 69 (9), 1189-1192

  • 香辛植物の抗酸化物質とその生体内酸化障害抑制作用

    菊﨑泰枝

    1995年03月, フードケミカル, 3, 49-53

  • スパイス・ハーブの化学と機能

    菊﨑泰枝

    1994年10月, 食品工業, 37 (19), 57-65

  • ハーブおよびその精油の抗菌作用と食品への応用

    菊﨑泰枝

    1994年09月, aromatopia, 9 (3), 42-46

  • ローズマリーの抗菌成分とその活性

    菊﨑泰枝

    1993年11月, aromatopia, 3 (4), 40-42

  • STRUCTURE OF ANTIOXIDATIVE COMPOUNDS OF GINGER

    H KIKUZAKI; Y KAWASAKI; N NAKATANI

    AMER CHEMICAL SOC, 1992年08月, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 204, 139 - AGFD, web_of_science

    研究発表ペーパー・要旨(国際会議)

  • 香辛料成分の構造特性と食品劣化抑制機能

    菊﨑泰枝; 中谷延二; 菊崎泰枝

    1992年03月, 食品と開発, 27 (3), 7-10

  • Structure of Iridoids from Swertia mileensis He et Shi

    菊﨑泰枝

    1988年12月, Chemistry Express, 3, 751-754

  • ナツメグ、メースの抗菌・抗酸化作用

    菊﨑泰枝; 中谷延二; 菊崎泰枝

    1988年02月, フードケミカル, 2, 70-74

  • 質量分析から得られる食品成分情報を活用した最近の研究

    菊﨑泰枝

    2020年10月, Food & Food Ingredients Journal of Japan, 225 (4), 339 - 345

    記事・総説・解説・論説等(その他)

  • 薬用植物を使用したアレルギー様食中毒予防の研究

    新田陽子; 菊﨑泰枝

    2020年12月30日, アレルギーの臨床, 40 (14), 50 - 52

    記事・総説・解説・論説等(学術雑誌)

書籍等出版物

  • スパイス・ハーブの機能と応用

    シーエムシー出版 (ISBN: 978-4-7813-1521-8)

  • 新スタンダード栄養・食物シリーズ5 食品学-食品成分と機能性-

    菊﨑泰枝; 久保田紀久 (, 範囲: 分担)

    東京化学同人, 2016年04月, 79-98, 107-108, 253-262 (ISBN: 9784807916658)

  • 栄養科学イラストレイテッド 食品学II 食品の分類と特性、加工を学ぶ

    菊﨑泰枝; 栢野新市 (, 範囲: 分担)

    羊土社, 2016年03月, 148-154 (ISBN: 9784758108805)

  • 管理栄養士のための経営管理 アメリカにおける考え方と実践を学ぶ

    菊﨑泰枝; 山中克己 (, 範囲: 分担)

    東京教学社, 2015年12月, 522-545 (ISBN: 9784808260439)

  • 栄養科学イラストレイテッド 食品学I 食品の成分と機能を学ぶ

    菊﨑泰枝; 水品善之他 (, 範囲: 編集)

    羊土社, 2015年11月, 90-91, 100-122 (ISBN: 9784758108799)

  • 新訂 食健康科学

    菊﨑泰枝; 小城勝相他 (, 範囲: 分担)

    放送大学教育振興会, 2015年03月, 27-62, 102-122 (ISBN: 9784595140471)

  • 抗酸化素材の開発と市場

    菊﨑泰枝; 山下栄次 (, 範囲: 分担)

    シーエムシー出版, 2014年05月, 47-62

  • 生食のおいしさとリスク

    菊﨑泰枝; 中谷延二 (, 範囲: 分担)

    エヌ・ティー・エス, 2013年06月, 459-466 (ISBN: 9784864690669)

  • 改訂版 食と健康

    菊﨑泰枝; 小城勝相他 (, 範囲: 分担)

    放送大学教育振興会, 2012年03月, 28-57, 103-119 (ISBN: 9784595313493)

  • スパイスなんでも小事典-おいしくて体によい使い方

    菊﨑泰枝; 久保田紀久 (, 範囲: 分担)

    講談社ブルーバックス, 2011年09月, 57-59, 81-83, 164-168 (ISBN: 9784062576987)

  • 栄養科学ファウンデーションシリーズ 給食経営管理論

    菊﨑泰枝; 青山京子他 (, 範囲: 分担)

    朝倉書店, 2011年03月, 1-4

  • 新版 食べ物と健康[食品学総論]

    菊﨑泰枝; 高岡素子他 (, 範囲: 分担)

    八千代出版, 2011年02月, 7-30, 55-75

  • 新しい食品加工学

    菊﨑泰枝; 的場輝佳 (, 範囲: 分担)

    南江堂, 2011年01月, 135-137

  • スパイス・ハーブの機能と最新応用技術

    菊﨑泰枝; 中谷延二 (, 範囲: 編集)

    シーエムシー出版, 2011年01月, 42-44、50-56、85-92、127-135

  • 健康と栄養のための有機化学

    菊﨑泰枝; 山本勇他 (, 範囲: 分担)

    建帛社, 2010年04月, 138-165

  • PDCAに基づく給食経営管理実習

    菊﨑泰枝; 上田伸男 (, 範囲: 分担)

    化学同人, 2009年04月, 13-14, 31-36

  • 食健康科学

    菊﨑泰枝; 中谷延二他 (, 範囲: 分担)

    放送大学教育振興会, 2009年03月, 101-148,254-265

  • スタンダード栄養・食物シリーズ5 食品学-食品成分と機能性 第2版

    菊﨑泰枝; 久保田紀久 (, 範囲: 分担)

    東京化学同人, 2008年09月, 76-96, 104-105, 257-265

  • 食品機能性の科学

    菊﨑泰枝; 荒井綜一 (, 範囲: 分担)

    2008年04月, 55-59、1042-1045

  • 栄養・食糧学用語辞典

    菊﨑泰枝; 青江誠一郎 (, 範囲: 分担)

    建帛社, 2007年10月

  • 管理栄養士コースで学ぶ?キャリアデザインのために?

    菊﨑泰枝; 吉池信男 (, 範囲: 分担)

    同文書院, 2007年04月, 60-62

  • 食品学実験

    菊﨑泰枝 (, 範囲: 編集)

    光生館, 2007年04月, 87-113, 148-153

  • 基礎調理実習 食品・栄養・大量調理へのアプローチ

    菊﨑泰枝; 小川宣子 (, 範囲: 分担)

    化学同人, 2007年03月, 65-83

  • 食品と技術・「大学の研究室-大阪市立大学大学院生活科学研究科食・健康科学講座菊﨑研究室-」

    菊﨑泰枝 (, 範囲: 筆頭著者)

    食品産業センター, 2007年01月, 10-13

  • 2007管理栄養士国家試験新全科の要点

    菊﨑泰枝; 青江誠一郎 (, 範囲: 分担)

    医歯薬出版, 2006年08月, 154-161, 428-429

  • 食と健康-食品の成分と機能

    菊﨑泰枝; 中谷延二他 (, 範囲: 分担)

    放送大学教育振興会, 2006年03月, 95-107,215-227

  • 栄養・食糧学データハンドブック

    菊﨑泰枝; 青山頼孝 (, 範囲: 分担)

    同文書院, 2006年01月, 191-193

  • 平成17年度大阪府栄養教諭免許法認定講習テキスト-学校栄養教育の理論と実践・栄養教育実習事前指導

    菊﨑泰枝; 山本由喜子 (, 範囲: 分担)

    2005年08月, 41-50

  • 2006新カリ対応管理栄養士国家試験完全攻略○×チェック実戦4000問

    菊﨑泰枝 (, 範囲: 分担)

    医歯薬出版, 2005年07月, 64-66、275-278

  • 生活科学I 食の科学

    菊﨑泰枝; 中谷延二他 (, 範囲: 分担)

    放送大学教育振興会, 2005年04月, 111-128, 200-220, 278-293

  • 読売ファミリー北版8月4日号・疑問解決隊-昆布はなぜ海の中でだしを出さないの

    菊﨑泰枝; 梅本ゆり子 (, 範囲: 監修)

    読売ファミリー編集部, 2004年08月

  • わたしの食卓3・ハーブとスパイス、本当の使い方を知っていますか?

    菊﨑泰枝; 中島さなえ (, 範囲: 監修)

    毎日新聞社, 2004年08月, 12-15、24-25、34-35

  • 新版 家政学事典

    菊﨑泰枝 (, 範囲: 分担)

    朝倉書店, 2004年07月, 430

  • 食生活研究・野菜の品質特性の変遷と食生活との関り(2)

    菊﨑泰枝; 阿部一博 (, 範囲: 分担)

    食生活研究会, 2004年07月, 14-21

  • 食生活研究・野菜の品質特性の変遷と食生活との関り(1)

    菊﨑泰枝; 阿部一博 (, 範囲: 分担)

    食生活研究会, 2004年05月, 13-22

  • 食べ物と健康 調理学

    菊﨑泰枝; 金谷昭子 (, 範囲: 分担)

    医歯薬出版, 2004年02月, 55-56、180-188、205-210、256-259

  • Oriental Foods and Herbs, Chemistry and Health Effects

    菊﨑泰枝 (, 範囲: 分担)

    American Chemical Society, 2003年09月, 176-189

  • 栄養科学シリーズNEXT-調理学実習

    菊﨑泰枝; 大谷貴美子 (, 範囲: 分担)

    講談社, 2003年04月

  • スタンダード栄養・食物シリーズ5 食品学-食品成分と機能性

    菊﨑泰枝; 久保田紀久 (, 範囲: 分担)

    東京化学同人, 2003年04月, 70-90、98-100、252-256

  • きょうどう・お料理サイエンス

    菊﨑泰枝 (, 範囲: 監修)

    コープこうべ, 2003年04月, 4-5

  • 食と健康-情報のウラを読む

    菊﨑泰枝; 村上明他 (, 範囲: 分担)

    丸善, 2002年11月, 173-198

  • 食品学実験書

    菊﨑泰枝; 藤田修三他 (, 範囲: 分担)

    医歯薬出版, 2002年08月, 108-116、132-135、191-196

  • 栄養と健康の専門知識がよくわかる食生活

    菊﨑泰枝 (, 範囲: 分担)

    全衛連「食生活」出版局, 2001年11月, 79-83

  • Quality Management of Nutraceuticals

    菊﨑泰枝 (, 範囲: 分担)

    American Chemical Society, 2001年01月, 230-240

  • AERA Mook-食生活学がわかる

    菊﨑泰枝; 木村修一 (, 範囲: 分担)

    朝日新聞社, 2000年11月, 132-135

  • Herbs, Botanicals & Teas

    菊﨑泰枝 (, 範囲: 分担)

    Technomic Publishing Co. Inc., 2000年06月, 75-105

  • 生活科学最前線90のトピック

    菊﨑泰枝; 倉戸ヨシヤ他 (, 範囲: 分担)

    中央法規出版, 1999年09月, 48-49

  • 抗酸化成分のすべて

    菊﨑泰枝; 二木鋭雄 (, 範囲: 分担)

    先端医学社, 1998年09月, 148-156

  • 食品総合辞典

    菊﨑泰枝; 五十嵐脩 (, 範囲: 分担)

    丸善, 1998年03月

  • 栄養学ハンドブック(第3版)

    菊﨑泰枝; 五明紀春 (, 範囲: 分担)

    技報堂出版, 1996年11月, 152-154

  • 活性酸素と医食同源

    菊﨑泰枝; 二木鋭雄 (, 範囲: 分担)

    共立出版, 1996年07月, 216-219

  • 昭和63年度健康情報調査報告書 香辛料

    菊﨑泰枝; 中谷延二他 (, 範囲: 分担)

    健康・体力づくり事業財団, 1989年03月, 364-391

  • 食品学 : 食品成分と機能性

    久保田, 紀久枝; 森光, 康次郎 (, 範囲: 第II部 食品の成分 10 嗜好成分-色素成分、呈味成分、注目されている嗜好成分の機能性)

    東京化学同人, 2021年03月, x, 292p, cinii_books (ISBN: 9784807916832)

  • スパイス・ハーブの機能と応用

    森川, 敏生 (, 範囲: 第4章4 フトモモ科(オールスパイス、クローブ), pp.121-130)

    シーエムシー出版, 2020年10月, vii, 353p, cinii_books (ISBN: 9784781315218)

講演・口頭発表等

  • 葛デンプン晒し液より単離した化合物の化学構造解析およびエストロゲン様活性の評価

    上山蓮実 , 菊崎泰枝 , 北瓜亮太 , 餅田尚子 , 松村羊子 , 栢野新市

    第73回日本栄養・食糧学会

    口頭発表(一般)

  • The inhibitory activity of ellagitannins on recombinant human histidine decarboxylase

    Yoko Nitta , Hideyuki Ito , Hirohumi Komori , Hiroshi Ueno , Hiroe Kikuzaki

    ICPH2019, 2019年11月28日, 2019年11月28日

    ポスター発表

  • Constituents of coriander leaves involved in antioxidant and anti-allergic activities

    Rika Ohara, Yurika Kitamura, Takuya Sugahara , Hiroyuki Onda , Nanami Yoshino , Hiroe Kikuzaki

    ICoFF2019, 2019年12月01日, 2019年12月01日

    ポスター発表

  • サバ筋肉中におけるヒスタミン生成を抑制するハーブ・スパイスの探索

    後藤茜; 山下慶子; 新田陽子; 菊﨑泰枝

    第33回日本香辛料研究会, 2018年11月, 一般社団法人日本香辛料研究会, 味の素株式会社クライアント・イノベーション・センター、神奈川県, false

  • 食用植物に含まれるヒスタミン産生抑制成分の探索

    菊﨑泰枝

    第6回奈良まほろば産学官連携懇話会, 2018年09月, 奈良まほろば産学官連携懇話会, 奈良女子大学、奈良県, false

  • 加熱調理がカロテノイド及びポリフェノール系成分由来の抗酸化力に及ぼす影響 人参の煮物の場合

    槇原咲貴; 高木陽子; 菊﨑泰枝

    日本調理科学会平成30年度大会, 2018年08月, 一般社団法人日本調理科学会, 武庫川女子大学 兵庫県, false

  • コリアンダー(Coriandrum sativum L.)葉茎部における抗酸化活性を指標とした含有成分の解明

    菊﨑泰枝; 小原理加; 恩田浩幸; 佐川岳人; 菊崎泰枝

    日本農芸化学会2017年度大会, 2018年03月, 日本農芸化学会, 名城大学、名古屋, false

  • さとうきび抽出物に含まれる脂質酸化抑制成分の探索と定量分析による主要成分の解明

    増田美穂子; 塩見和世; 水雅美; 菊﨑泰枝

    第56回日本栄養・食糧学会近畿支部大会, 2017年11月, 日本栄養・食糧学会近畿支部, 龍谷大学瀬田キャンパス, false

  • コリアンダー(Coriandrum sativum L.)の抗酸化性

    小原理加; 恩田浩幸; 佐川岳人; 菊﨑泰枝

    第32回日本香辛料研究会, 2017年09月, 日本香辛料研究会, 兵庫大学, false

  • ローズレッドペタルに含まれるフラボノイド配糖体のヒスチジン脱炭酸酵素阻害活性と阻害様式

    山下慶子; 新田陽子; 菊﨑泰枝

    第71回日本栄養・食糧学会大会, 2017年05月, 日本栄養・食糧学会, 琉球大学, false

  • ローズレッドペタルに含まれるフラボノイド配糖体のヒスチジン脱炭酸酵素阻害活性

    山下慶子; 新田陽子; 菊﨑泰枝

    第21回日本フードファクター学会学術集会, 2016年11月, 日本フードファクター学会, 富山国際会議場 富山市, false

  • アメリカのFood Serviceテキストと日本の給食経営管理論教科書との比較

    菊﨑泰枝

    第12回日本給食経営管理学会学術総会, 2016年11月, 日本給食経営管理学会, 大手前大学 さくら夙川キャンパス 兵庫県西宮市, false

  • ショウガ科香辛料に含まれる機能物質の探索

    菊﨑泰枝

    第60回香料・テルペンおよび精油化学に関する討論会, 2016年10月, 香料・テルペンおよび精油化学に関する討論会, 東京農業大学オホーツクキャンパス 網走市, false

  • さとうきび抽出物に含まれる脂質酸化抑制成分

    増田美穂子; 金井彩; 塩見和世; 水雅美; 小林慧子; 菊﨑泰枝

    日本油化学会第55回年会, 2016年09月, 日本油化学会, 奈良女子大学 奈良市, false

  • ポリフェノール含量の多い食材及び料理の抗酸化力の評価-ビタミンCの影響について

    白川みどり; 阿萬友理恵; 小林慧子; 菊﨑泰枝

    日本調理科学会平成28年度大会, 2016年08月, 日本調理科学会, 名古屋学芸大学 名古屋市, false

  • メチル化カテキンによる分泌型スフィンゴミエリナーゼ阻害作用

    小林慧子; 石﨑有希; 小城勝相; 菊﨑泰枝

    第70回日本栄養・食糧学会大会, 2016年05月, 日本栄養・食糧学会, 武庫川女子大学, false

  • 抗酸化物質による分泌型スフィンゴミエリナーゼ阻害作用

    小林慧子; 稲垣香奈; 宮本萌; 石﨑有希; 菊﨑泰枝

    第9回日本ポリフェノール学会学術大会, 2015年08月, 日本ポリフェノール学会, 奈良女子大学、奈良市, false

  • Inhibition of secretory sphingomyelinase by epicatechin 3-O-gallate

    菊﨑泰枝

    ACN2015 Asian Congress of Nutrition, 2015年05月, Japan Society of Nutrition and Food Science, Yokohama, Japan, true

  • エピカテキンガレートによる分泌型スフィンゴミエリナーゼ阻害作用

    小林慧子; 石﨑有希; 宮本萌; 菊﨑泰枝

    第87回日本生化学会大会, 2014年10月, 京都国際会館、京都, false

  • カテキン類による分泌型スフィンゴミエリナーゼの阻害作用に関する研究

    石﨑有希; 宮本萌; 小林慧子; 菊﨑泰枝

    日本家政学会関西支部第36回(通算92回)研究発表会, 2014年10月, 日本家政学会関西支部, 京都聖母女学院短期大学、京都, false

  • Inhibitory effects of polyphenols in Rosa gallica on recombinant human histidine decarboxylase

    菊﨑泰枝

    XXVIIth International Conference of Polyphenols & 8th Tannin Conference, 2014年09月, ICP2014, Nagoya University, Nagoya, true

  • ORACを指標とした食品の抗酸化力評価の食事管理への活用の検討

    菊﨑泰枝; 湯川梨紗; 中屋麻衣; 源馬絵美; 中村美月; 小林慧子

    日本調理科学会平成26年度大会, 2014年08月, 日本調理科学会, 広島市 県立広島大学, false

  • エピガロカテキンガレートの分泌型スフィンゴミエリナーゼ阻害活性

    小林慧子; 石﨑有希; 宮本萌; 菊﨑泰枝

    第68回日本栄養・食糧学会大会, 2014年06月, 札幌市 酪農学園大学, false

  • Rosa gallicaの花弁に含まれるヒスチジン脱炭酸酵素阻害活性成分の探索

    秋本梢; 渡辺裕香; 新田陽子; 植野洋志; 小林慧子; 菊﨑泰枝

    日本農芸化学会2014年度大会, 2014年03月, 神奈川県 明治大学, false

  • 香辛料の抗酸化機能-オールスパイス-

    菊﨑泰枝

    第20回スパイス&ハーブ研究成果セミナー, 2013年11月, 公益財団法人 山崎香辛料振興財団, 東京都 エスビー食品㈱スパイスセンター, false

  • apoE欠損マウスの老化に伴う分泌型スフィンゴミエリナーゼ活性とセラミド量の変化

    小林慧子; 永田絵理; 佐々木香月; 小城勝相; 菊﨑泰枝

    第86回日本生化学会大会, 2013年09月, 横浜, false

  • ORACを指標とした野菜および野菜料理の抗酸化力の評価

    湯川梨紗; 中屋麻衣; 小林慧子; 菊﨑泰枝

    日本調理科学会平成25年度大会, 2013年08月, 日本調理科学会, 奈良市 奈良女子大学, false

  • 食品ゲルのテクスチャーとフレーバーリリース\n寒天ゲルからのショ糖のリリース-寒天濃度、ショ糖濃度、ゲル調製法の影響-

    菊﨑泰枝

    日本食品科学工学会第60回記念大会 シンポジウムB1「食品ゲルのテクスチャーとフレーバーリリース」, 2013年08月, 東京都 実践女子大学, false

  • apoE欠損型マウスにおける老化に伴う動脈硬化進行とセラミド動態に関する研究

    小林慧子; 永田絵理; 佐々木香月; 斯波真理子; 小城勝相; 菊﨑泰枝

    第67回日本栄養・食糧学会大会, 2013年05月, 名古屋市 名古屋大学, false

  • 酵素グルコシダーゼや腸管モデル培養細胞を用いた配糖体Leptosinの代謝研究

    菊﨑泰枝; 荒木 裕佳子; 伊藤 美紀子; 加藤 陽二; 菊崎 泰枝; 北元 憲利; 松本 大樹; 室田 佳恵子

    日本農芸化学会2013年度大会, 2013年03月, 日本農芸化学会, 東北大学, false

  • マヌカ蜂蜜から発見された新規配糖体の単離と酵素を用いた構造解析

    加藤陽二; 松本大樹; 荒木裕佳子; 北元憲利; 菊﨑泰枝

    第17回日本フードファクター学会学術集会, 2012年11月, 日本フードファクター学会, 静岡, false

  • Isoflavone C-glycosides isolated from the root of Kudzu (Pueraria lobata) and their estrogenic activities

    菊﨑泰枝

    2012 EFFoST Annual Meeting, 2012年11月, European Federation of Food Science and Technology, Montpellier, France, true

  • 給食経営管理実習を利用したエネルギー教育の試み~定格消費電力と作業工程表に基づいた消費電力量の予測と実測~

    山形純子; 小林慧子; 伊與田浩志; 菊﨑泰枝

    第8回日本給食経営管理学会学術総会, 2012年11月, 日本給食経営管理学会, 名古屋女子大学汐路学舎, false

  • ショ糖添加寒天ゲルからのショ糖のリリースと甘味強度

    菊﨑泰枝; クンヤン, ゼンワン; 西成勝好; 菊崎泰枝; 早川文代; 神山かおる

    日本調理科学会平成24年度大会, 2012年08月, 日本調理科学会, 秋田大学, false

  • ショウガ科植物Kaempferia parviflora根茎に含まれる熱に安定な色素について

    菊﨑泰枝; 菊崎泰枝; 中村仁美; 小林慧子; 東鋭明; 田中康雄; 中谷延二

    日本調理科学会平成24年度大会, 2012年08月, 日本調理科学会, 秋田大学, false

  • Sucrose release from agar gels as studied by uniaxial compression and sensory evaluation

    菊﨑泰枝

    2nd International Conference of Food Oral Processing, Physics, Physiology and Psychology of Eating, 2012年07月, the Institut National de la Recherche Agronomique and the Royal Society of Chemistry, Beaune, France, true

  • 食品ゲルのテクスチャーとフレーバーリリース 1.ショ糖添加寒天ゲルからのショ糖のリリース

    菊﨑泰枝; 菊崎泰枝; 大倉花鈴; 西成勝好

    日本家政学会第64回大会, 2012年05月, 日本家政学会, 大阪市立大学, false

  • 食品ゲルのテクスチャーとフレーバーリリース 2.ショ糖添加寒天ゲルからのショ糖のリリース

    菊﨑泰枝; 西成勝好; Wang Zheng; Yang Kun; 菊崎泰枝

    日本家政学会第64回大会, 2012年05月, 日本家政学会, 大阪市立大学, false

  • Kaempferia parvifloraから得られたメトキシフラボンの抗アレルギー作用

    小林彰子; 田辺創一; 田中康雄; 東鋭明; 菊﨑泰枝

    第66回日本栄養・食糧学会大会, 2012年05月, 仙台市 東北大学, false

  • マヌカ蜂蜜に由来する新規配糖体Leptosinのケミカルマーカーとしての有用性について

    加藤陽二; 梅田菜月; 前田明日菜; 松本大樹; 北元憲利; 菊﨑泰枝

    日本農芸化学会2012年度大会, 2012年03月, 日本農芸化学会, 京都女子大学, false

  • 食用植物に含まれる機能性成分の化学構造と活性

    菊﨑泰枝

    地域イノベーション戦略支援プログラム 和歌山県紀北紀中エリア\n平成23年度第2階研究交流会, 2011年12月, 公益財団法人わかやま産業振興財団、和歌山県, 和歌山市, false

  • 給食経営管理実習中のガス・電力消費量の「見える化」および測定によるエネルギー教育の試み

    山形純子; 小林慧子; 伊與田浩志; 茅野友広; 上田由喜子; 菊﨑泰枝

    第7回日本給食経営管理学会学術総会, 2011年11月, 日本給食経営管理学会, 大妻女子大学千代田キャンパス, false

  • Novel Chemical Marker of Nanuka Honey

    菊﨑泰枝

    2011 International Conference on Food Factors, 2011年11月, 2011 International Conference on Food Factors, Taipei, Taiwan, true

  • さとうきび抽出物による鮭の退色抑制効果

    岸映里; 塩見和世; 水雅美; 河合俊和; 佐藤彩加; 宮下裕幸; 池田剛; 菊﨑泰枝

    日本調理科学会平成23年度大会, 2011年08月, 日本調理科学会, 高崎健康福祉大学, false

  • 食品ゲルのレオロジー特性とフレーバーリリース

    西成勝好; Wang Zheng; 菊﨑泰枝

    日本調理科学会平成23年度大会, 2011年08月, 日本調理科学会, 高崎健康福祉大学, false

  • 葛デンプン晒し液より単離したイソフラボンのエストロゲン様活性及び抗変異原性の評価

    栢野新市; 土田真由香; 柳澤尚子; 松村羊子; 菊﨑泰枝; 北田善三

    第65回日本栄養食糧学会大会, 2011年05月, 日本栄養・食糧学会, false

  • メドウスウィート(Filipendula ulmaria)成分によるヒスチジン脱炭酸酵素阻害機構の解明

    新田陽子; 東鋭明; 袁野; 菊﨑泰枝; 植野洋志

    第25回日本香辛料研究会, 2010年11月

  • メドウスウィート(Filipendula ulmaria)のヒスチジン脱炭酸酵素阻害成分の探索

    菊﨑泰枝; 東鋭明; 袁野; 新田陽子; 植野洋志

    第15回日本フードファクター学会学術集会, 2010年10月, 仙台, false

  • タイ原産ナス(Solanum sanitwongsei)の成分

    今井希; 岩本嗣; 小西洋太郎; 菊﨑泰枝

    日本栄養・食糧学会第49回近畿支部大会, 2010年10月, false

  • 給食経営管理実習中のガス消費量「見える化」によるエネルギー教育の試み

    山形純子; 伊與田浩志; 茅野友広; 小西洋太郎; 菊﨑泰枝; 赤尾正; 藤原政嘉

    第6回日本給食経営管理学会学術総会, 2010年10月, false

  • 大阪特産野菜「葉ゴボウ」に含まれる抗酸化成分の定量と抗酸化成分に対する加熱調理の影響

    菊﨑泰枝; 岸田利恵; 岩本嗣

    日本調理科学会平成22年度大会, 2010年08月, false

  • ショウガ科植物Kaempferia parvifloraに含まれるフラボノイドの抗変異原性

    東鋭明; 栢野新市; 鷹屋潤氏; 古閑丸典子; 石田達也; 田井勇毅; 田中康雄; 菊﨑泰枝

    第64回日本栄養・食糧学会大会, 2010年05月, false

  • 葛デンプン晒し液より単離したイソフラボンC-配糖体の化学構造およびエストロゲン様活性

    栢野新市; 長山明日香; 小林真弓; 川端菜美; 松村羊子; 菊﨑泰枝; 北田善三

    第64回日本栄養・食糧学会大会, 2010年05月, false

  • Kaempferia parvifloraの抗アレルギー成分

    小林彰子; 東鋭明; 岡平早希; 相場由貴; 田中康雄; 田辺創一; 菊﨑泰枝

    第64回日本栄養・食糧学会大会, 2010年05月, 徳島, false

  • ゲットウ (Alpinia zerumbet (Pers.)Burtt and Smith) 種子に含まれる膵リパーゼ阻害成分の解明

    伊庭友香; 中谷延二; 菊﨑泰枝

    日本農芸化学会2010年度大会, 2010年03月, false

  • マンゴージンジャー(Curcuma amada)に含まれるジテルペノイドの構造

    東鋭明; 篠田さやか; 山口泰永; 高柿了士; 菊﨑泰枝

    第53回香料・テルペンおよび精油化学に関する討論会, 2009年11月, false

  • オンジ(Polygala tenuifolia)からの1,5-アンヒドログルシトールの精製と単離

    金一玲; 古閑丸典子; 菊﨑泰枝; 小西洋太郎

    第48回日本栄養・食糧学会近畿支部大会, 2009年11月, false

  • ローズマリーに含まれるポリフェノールの抗酸化能

    岸映里; 秋山香代; 中谷延二; 菊﨑泰枝

    第14回日本フードファクター学会学術集会, 2009年11月, false

  • メドウスウィート(Filipendula ulmaria (L.) Maxim.)に含まれるヒスチジン脱炭酸酵素阻害成分

    袁野; 東鋭明; 新田陽子; 植野洋志; 菊﨑泰枝

    第24回日本香辛料研究会, 2009年11月, false

  • Multiple Functions in Ginger Family

    菊﨑泰枝

    Italy-Japan Symposium on "Foods and Health: past, present and future", 2009年10月, Intituo Italiano di Culture, Tokyo, Japan, true

  • アレルギー対応クッキーの品質特性-生地を真空包装し冷凍保存した場合-

    菊﨑泰枝; 岡本夕佳; 山形純子; 伊與田浩志; 藤原政嘉

    第5回日本給食経営管理学会学術総会, 2009年10月, false

  • 給食経営管理実習時のガス消費量の「見える化」による省エネ意識の変化

    山形純子; 伊與田浩志; 菊﨑泰枝; 赤尾正; 西村伸也; 藤原政嘉

    第5回日本給食経営管理学会学術総会, 2009年10月, false

  • 皮茸(コウタケ)の抗酸化性および抗変異原性の評価

    松村羊子; 南幸; 菊﨑泰枝; 栢野新市

    第56回日本栄養改善学会学術総会, 2009年09月, false

  • 低アレルゲン大豆「なごみまる」のイソフラボンおよび脂肪酸分析と「なごみまる」を原料とした味噌の官能評価

    菊﨑泰枝; 久米みゆき; 森山達哉; 小川正; 河智義弘

    日本調理科学会平成21年度大会, 2009年08月, false

  • ナス果肉から単離した成分の抗酸化性の定量的評価

    古閑丸典子; 鷹屋潤氏; 長山明日香; 小林真弓; 菊﨑泰枝; 南幸; 栢野新市

    第63回日本栄養・食糧学会大会, 2009年05月, false

  • 葛デンプン晒し液より単離したイソフラボンのエストロゲン様活性の評価

    小林真弓; 長山明日香; 鷹屋潤氏; 古閑丸典子; 松村羊子; 菊﨑泰枝; 北田善三; 栢野新市

    第63回日本栄養・食糧学会大会, 2009年05月, false

  • ショウガ科植物Kaempferia parvifloraに含まれる色素の構造と熱安定性

    東鋭明; 遠藤瑶子; 田中康雄; 菊﨑泰枝

    第23回日本香辛料研究会, 2008年11月, false

  • ヒスタミン合成を阻害するオールスパイス成分の探索

    新田陽子; 菊﨑泰枝; 植野洋志

    第13回日本フードファクター学会, 2008年11月, false

  • スチームコンベクションオーブン加熱における庫内水蒸気濃度が食品の昇温に与える影響

    山形純子; 伊與田浩志; 西村伸也; 菊﨑泰枝; 藤原政嘉

    第4回日本給食経営管理学会学術総会, 2008年11月, false

  • Radical scavenging and hyaluronidase inhibitory activities of constituents in Japanese vegetables, Arctiun lappa and Petasites japonicus

    菊﨑泰枝

    Italian-Japanese Joint Symposium-Natural products and functional foods, 2008年06月, Salerono, Italy, true

  • Search for antioxidants in spices and herbs

    菊﨑泰枝

    Joint symposium-Natural products and functional foods, 2008年06月, Salerno, Italy, true

  • 葛デンプン晒し液から単離したイソフラボンの構造解析および抗変異原性の評価

    栢野新市; 鈴木慶一; 伊庭友香; 広原里紗; 宮内美名; 菊﨑泰枝; 北田善三

    第62回日本栄養・食糧学会大会, 2008年05月, false

  • 葉ゴボウ(Arctium lappa)のルチンとクロロゲン酸含量

    岩本嗣; 田崎弘之; 鈴木千代実; 菊﨑泰枝

    第62回日本栄養・食糧学会大会, 2008年05月, false

  • パプアナツメグ、パプアメース(Myristica argentea)に含まれるリグナンのラジカル捕捉活性評価

    秋山香代; 中谷延二; 中谷和世; 菊﨑泰枝

    第62回日本栄養・食糧学会大会, 2008年05月, false

  • 黒ショウガ(Kaempferia parviflora)根茎に含まれる新規配糖体の構造

    東鋭明; 田中康雄; 菊﨑泰枝

    日本薬学会第128年会, 2008年03月, false

  • ショウガ科植物に含まれる一酸化窒素産生抑制成分

    高橋周; 村上明; 山本憲朗; 東鋭明; 秋山香代; 菊﨑泰枝; 中谷延二

    日本農芸化学会2008年度大会, 2008年03月, false

  • スチームコンベクションオーブンを利用した加熱調理の特性と給食経営管理における有用性の検討

    菊﨑泰枝; 御前加奈; 岡本夕佳; 山形純子; 伊與田浩志; 藤原政嘉

    第3回日本給食経営管理学会学術総会, 2007年11月, false

  • スチームコンベクションオーブンの使用形態とエネルギー消費

    山形純子; 伊與田浩志; 西村伸也; 菊﨑泰枝; 藤原政嘉

    第3回日本給食経営管理学会学術総会, 2007年11月, false

  • Antimicrobial activity of saponins from leaves of Bacopa monnieri against yeast

    菊﨑泰枝

    International Conference of Food Factors for Health Promotion-ICoFF2007, 2007年11月, true

  • Constituents Enhancing eNOS Protein Expression in the Fruits of Piper longum

    菊﨑泰枝

    International Conference of Food Factors for Health Promotion-ICoFF2007, 2007年11月, true

  • Search for Zingiberaceae Phytochemicals that Suppress NO Generation from Stimulated Macrophages

    菊﨑泰枝

    International Conference on Food Factors for Health Promotion-ICoFF2007, 2007年11月, true

  • Radical Scavenging Capacity of Tannins and Flavonoids Isolated from Salam Leaf (Syzygium polyanthum)

    菊﨑泰枝

    ICPH2007-3rd International Conference of Polyphenols and Health, 2007年11月, true

  • 大阪産野菜「葉ごぼう」のラジカル捕捉活性について

    鈴木千代実; 岩本嗣; 菊﨑泰枝

    日本家政学会関西支部第29回研究発表会, 2007年10月, false

  • Synergistic Growth Inhibitory Effect ofConstituents of Cape Aloe Extract in Ehrlich Ascites Tumor Cells

    菊﨑泰枝

    10th Asian Congress of Nutrition, 2007年08月, true

  • 黒ショウガ(Kaempferia parviflora)に含まれるフラボノイドのNO産生抑制活性

    東鋭明; 菊﨑泰枝; 田中康雄; 高橋周; 村上明; 大東肇

    第61回日本栄養・食糧学会大会, 2007年05月, false

  • フキ葉身の栄養成分分析

    岩本嗣; 西村勉; 田崎弘之; 菊﨑泰枝

    第61回日本栄養・食糧学会大会, 2007年05月, false

  • Constituents of coriander leaves involved in antioxidant and anti-allergic activities

    Rika Ohara; Yurika Kitamura; Takuya Sugahara; Hiroyuki Onda; Nanami Yoshino; Hiroe Kikuzaki

    ICoFF2019, 2019年12月04日, 2019年12月01日, 2019年12月01日

  • The inhibitory activity of ellagitannins on recombinant human histidine decarboxylase

    Yoko Nitta; Hideyuki Ito; Hirohumi Komori; Hiroshi Ueno; Hiroe Kikuzaki

    ICPH2019, 2019年11月29日, 2019年11月28日, 2019年11月28日

  • 葛デンプン晒し液より単離した化合物の化学構造解析およびエストロゲン様活性の評価

    上山蓮実; 菊崎泰枝; 北瓜亮太; 餅田尚子; 松村羊子; 栢野新市

    第73回日本栄養・食糧学会, 2019年05月18日

担当経験のある科目(授業)

  • 教職実践演習 (奈良女子大学)

  • パサージュ(25A) (奈良女子大学)

  • 事前・事後指導(栄養) (奈良女子大学)

  • 栄養教育実習 (奈良女子大学)

  • 食品機能管理学特論B (奈良女子大学)

  • 有機化学Ⅰ (奈良女子大学)

  • 給食経営管理学Ⅱ (奈良女子大学)

  • 給食経営管理学Ⅰ (奈良女子大学)

  • 食物栄養学研究法 (奈良女子大学)

  • 栄養学総合演習 (奈良女子大学)

  • 食物科学概論 (奈良女子大学)

  • 分子調理科学特論演習 (奈良女子大学)

  • 分子調理科学特論 (奈良女子大学)

  • 食品化学総論(A) (奈良女子大学)

  • 有機化学 I (奈良女子大学)

  • 食品化学総論(B) (奈良女子大学)

  • 食品機能管理学特論B (奈良女子大学)

  • 食品機能管理学特論A (奈良女子大学)

  • 給食経営管理学臨地実習 (奈良女子大学)

  • 給食経営管理学実習 (奈良女子大学)

  • 生活と科学 (奈良女子大学)

  • 食品化学総論 (奈良女子大学)

  • 給食経営管理学 II (奈良女子大学)

  • 給食経営管理学 I (奈良女子大学)

  • 分子食品・調理科学特論 (奈良女子大学)

所属学協会

  • 日本農芸化学会

  • 日本栄養・食糧学会

  • 日本調理科学会

  • 日本家政学会

  • 日本給食経営管理学会

  • 日本栄養改善学会

  • 日本油化学会

  • 日本薬学会

  • 日本生薬学会

  • 日本フードファクター学会

  • 日本香辛料研究会

  • 植物化学研究会

  • 香料・テルペンおよび精油化学に関する討論会

  • AOU研究会

  • 抗酸化・機能研究会

Works(作品等)

  • さとうきび由来成分による食品中の油脂酸化抑制に関する研究

    2014年06月 - 2015年03月

  • さとうきび由来成分による食品中の油脂酸化抑制に関する研究

    2013年06月 - 2014年03月

  • ごぼうの有効成分の単離、同定に関する研究

    2012年06月 - 2013年03月

  • さとうきび由来成分による食品への抗酸化作用に関する研究

    2012年06月 - 2013年03月

  • さとうきび抽出物の成分解明及び食品に対する抗酸化作用に関する研究

    2011年06月 - 2012年03月

  • さとうきび抽出物の抗酸化性について

    2009年06月 - 2010年03月

  • アレルギー除去食品の開発及び幼稚園献立の監修

    2006年08月 - 2007年07月

  • サクラダソウの成分分析

    2006年04月 - 2007年03月

  • ヒハツの機能性成分の解明

    2005年 - 2007年

  • マンゴージンジャーの機能性成分の解明

    2004年 - 2007年

  • 化粧品原料ローズマリーエキスの成分分析

    2006年01月 - 2006年06月

  • カワラヨモギの機能成分の解析

    2004年07月 - 2005年06月

  • 黒ショウガ成分の構造解明

    2004年07月 - 2005年06月

  • 竹に含まれる機能成分の解明

    2004年06月 - 2005年05月

  • プルーン(Prunus domestica L.)に含まれる生理活性物質の精査研究

    2003年11月 - 2004年10月



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