NISHIMAKI Mio

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Profile and Settings

• Name (Japanese)

  Nishimaki

• Name (Kana)

  Mio

Degree

• Doctor of Sport Sciences, Waseda University

Research Experience

• Apr. 2020, Mar. 2021, 国立大学法人三重大学医学系研究科 産婦人科講座, 博士研究員
• Apr. 2015, Mar. 2020, Japan Institute of Sport Sciences
• Apr. 2021, Mar. 2022, Doshisha University, Faculty of Health and Sports Science, 助手

Education

• Waseda University, Graduate School of Sport Sciences
• Shigakkan University, Graduate School of Wellness
• Shigakkan University, Faculty of Wellness

Teaching Experience

• Outlines of Health Science1, Nara Women's University, Oct. 2022, 9999
• Diet and Environment, Nara Women's University, Oct. 2022, 9999
• Health Science Research Seminar 1, Nara Women's University, Apr. 2022, 9999
• Research Ethics in Studies of Human Life and Environment, Nara Women's University, Apr. 2023, Mar. 2024
• Special Course in Health Science A, Nara Women's University, Apr. 2024, 9999, Postgraduate courses
• Outlines of Health Science1, Nara Women's University, Apr. 2024, 9999

Ⅱ．研究活動実績

Published Papers

• Refereed, Journal of Dietary Supplements, Informa UK Limited, Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate Ingestion on Muscle Damage after Eccentric Exercise in Healthy Males: A Pilot Placebo-Controlled Double-Blind Crossover Study, Yoko Tanabe; Nobuhiko Akazawa; Mio Nishimaki; Kazuhiro Shimizu; Naoto Fujii; Hideyuki Takahashi, An animal study demonstrated that 6-(Methylsulfinyl)hexyl isothiocyanate (6-MSITC), a major bioactive compound in Japanese pungent spice wasabi, has an action of inhibiting the activation of calpain-1 (a protease). Increases in calpain activity can cause continual strength loss after eccentric exercise. It remains to be determined in humans whether 6-MSITC intake would modulate calpain and/or muscle damage responses after eccentric exercise. We performed a randomized, double-blind, crossover design study wherein eight healthy young males were randomly assigned to ingest 9 mg/day of 6-MSITC or placebo from 1 day before exercise to 4 days after exercise (30 maximal isokinetic eccentric contractions of the elbow flexors using an isokinetic dynamometer). Calpain-1 concentration, inflammatory and muscle damage markers (creatine kinase activity, urinary titin concentration, muscle strength, range of motion, muscle soreness and transverse relaxation time) were assessed. Plasma calpain-1 concentration after eccentric exercise was similar between the placebo- and 6-MSITC-treated conditions. All muscle damage and inflammatory markers were not affected by 6-MSITC relative to those in the placebo-treated condition. Our results suggest that 6-MSITC has no effect on plasma calpain-1 concentration and muscle damage and inflammatory markers measured after eccentric exercise., 03 May 2021, 1, 15, Scientific journal, True, 10.1080/19390211.2021.1912244

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• Refereed, The Journal of sports medicine and physical fitness, The link between the range of rapid weight loss and physical conditions of elite wrestlers during competition under the morning weigh-in rule., Emi Kondo; Mio Nishimaki; Daichi Yamashita; Kohei Nakajima, BACKGROUND: Amateur wrestlers have often undergone rapid weight loss (RWL) to win their matches. On January 1, 2018, the rule of weigh-in was changed and weight category increased. The study aimed to determine the prevalence of wrestlers undergoing RWL under the new rule of morning weigh-in before the tournament and examine the relationship between the range of RWL and physical conditions. METHODS: Male (n = 204) and female (n = 50) wrestlers participating in the National Wrestling Championship completed a questionnaire about weight reduction methods and their physical condition. RESULTS: Among 159 participants exceeding their weight class one-week before competition, 36% of males and 44% of females exceeded their weight class by 0.0-4.9% (requiring small RWL); 30% of males and 6% of females exceeded by 5.0-10.0% (requiring large RWL), but neither the males nor females were over 10.0% above required weight. In the males, there was a moderate negative correlation between excess rates of body mass one-week before competition and their physical condition (r = -0.330 to -0.467, P < 0.05) on the first day of the competition; however, no significant correlation was found in the females. Comparing physical condition according to the range of RWL, there were significantly lower scores in the large RWL group (≥ 4.9%) than the small RWL group (< 4.9%) in males. CONCLUSIONS: We found that RWL ≤ 5% is most appropriate to ensure better physical condition of wrestlers on competition day., 23 Jul. 2020, 61, 1, 117, 123, Scientific journal, True, 10.23736/S0022-4707.20.11221-0

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• Refereed, Journal of High Performance Sport, Japan Institute of Sports Sciences, Japan Sport Council, Prevalence, methods of rapid weight loss amongst elite Japanese wrestlers:a questionnaire-based study of the 2016 Japanese Wrestling Championship, Mio NishimakiEmi KondoCheryl TeoKohei NakajimaDaichi Yamashita, This study aims to investigate weight loss practices of elite Japanese wrestlers who participated at the 2016 Japanese Wrestling Championship. In this study, we defined rapid weight loss (RWL) as losing 5% or more of their weight relative to their intended weight class, one week before weigh-in. 241 wrestlers completed a questionnaire on their weight loss practices. 109 wrestlers reported RWL and were used for analysis. We found that wrestlers who cut weight over a longer duration utilized a greater variety of weight loss methods than those who cut weight over a shorter duration. Reduced carbohydrate intake was commonly used by wrestlers who cut weight over a longer duration utilized a greater variety of weight loss methods than those who cut weight over a shorter duration. Dehydration was commonly done by all wrestlers. We also identified that the use of low carbohydrate and low salt diets are not optimized for RWL, and suggest for wrestlers to be educated to improve the effectiveness of these methods. Studies to investigate the revision of the weigh-in rules are recommended to better understand the implications of these changes on RWL and recovery practices in wrestlers., Feb. 2020, 6, 0, 12, 27, Scientific journal, JHPS‐本文（西牧未央、近藤衣美、Cheryl Teo、中嶋耕平，山下大地）.pdf, False, 10.32155/jissjhps.6.0_12

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• Refereed, Journal of High Performance Sport, Japan Institute of Sports Sciences, Japan Sport Council, Body Composition, Muscle Strength, Power, and Endurance of Elite Male Japanese Freestyle Wrestlers, Yamashita Daichi; Nishimaki Mio; Nagao Hideyuki; Ikeda Michio; Numata Mikio; Inoue Kenji; Nishiguchi Shigeki, Wrestlers are categorized into a series of weight classes to ensure fair competition. Since the implementation of new rules in January 2018, weight categories and the timings of weigh-ins have changed. The purpose of the study was to establish baseline physical profiles, such as body composition, muscle strength, power, and endurance for Japanese elite freestyle wrestlers in each of the new weight classes. We collected a total of 242 data points from 70 elite Japanese male freestyle wrestlers at 14 training camps over two years. Body composition measurements, one-repetition maximum tests (bench press, parallel back squat, one-handed dumbbell snatch, and weighted chinup) and muscle endurance tests (pull-up) were performed. Body fat percentages for wrestlers in the 86-kg class or below were from 9.1% to 11.6%, whereas body fat percentages for wrestlers in the 92-, 97-, and 125-kg classes were 14.0 ± 3.5, 19.8 ± 6.9, and 26.6 ± 3.4%, respectively. This result suggests that the wrestlers in the heavier weight classes have a higher capacity to reduce body fat and increase muscle mass, which is essential if they improve strength and power. Absolute muscle strength and power performance tended to increase with heavier classes (the major results were as follows: 1RM bench press: 88.0 ± 13.0 kg in the 57-kg class and 142.0 ± 13.0 kg in the 125-kg class), whereas these relative values tended to decrease with heavier classes. Muscle endurance performance tended to decrease with heavier classes (the pull-up test: 23.8 ± 1.5 repetitions in the 61-kg class and 10.0 ± 5.4 repetitions in the 125-kg class). This study provides baseline data that can be used in the prescription of individual training programs for wrestlers, assessing areas of strength and weakness, and developing the wrestler's technical-tactical strategies., 2020, 6, 0, 33, 43, Scientific journal, 6_33.pdf, False, 10.32155/jissjhps.6.0_33

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• Refereed, International Journal of Environmental Research and Public Health, MDPI AG, When and How Should Chinese Pregnant Women Exercise? A Longitudinal Study in China, Mi Xiang; Masayuki Konishi; Huanhuan Hu; Mio Nishimaki; Hyeon-Ki Kim; Hiroki Tabata; Hisao Shimizu; Yue Fang; Xueyuan Li; Jiawei Xu; Zhiruo Zhang; Huigang Liang; Takashi Arao; Shizuo Sakamoto, This study aimed to examine when and how physical activity (PA) influences gestational weight gain (GWG) and infant birthweight (BW) by considering the PA’s total volume, timing, intensity, and type, controlling for the influence of energy intake. A total of 1272 participants in different stages of pregnancy were recruited from hospital. The associations between PA and GWG or BW in the latter half of pregnancy were significant. Women with the highest PA volume in the third trimester had significantly lower risks of inadequate and excessive GWG by 69% (OR = 0.31, 95%CI: 0.10–0.91) and 67% (OR = 0.33, 95% CI: 0.12–0.91), respectively, compared to women in the lowest quartile. Women who achieved the recommended moderate intensity of PA during their second and third trimesters, independent of total volume of PA, had infants with significantly lower BWs compared to those who did not (β = −0.15, SE = 66.33, p = 0.04; β = −0.20, SE = 64.54, p = 0.01, respectively). Therefore, the effects of total volume and intensity of PA on GWG and BW were different. Interventions to prevent inappropriate GWG and macrosomia may need to set different priorities and timing regarding total volume or intensity of PA., 25 Dec. 2019, 17, 1, 180, 180, Scientific journal, True, 10.3390/ijerph17010180

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• Refereed, BMC Pregnancy and Childbirth, Physical activity and dietary intake among Chinese pregnant women: An observational study, Mi Xiang; Jing Zhang; Huigang Liang; Zhiruo Zhang; Masayuki Konishi; Huanhuan Hu; Mio Nishimaki; Hyeon Ki Kim; Hiroki Tabata; Hisao Shimizu; Takashi Arao; Shizuo Sakamoto, © 2019 The Author(s). Background: Physical activity (PA) and dietary intake are important modifiable factors associated with health outcomes. However, Chinese pregnant women's PA and dietary intake are only vaguely understood. The aim of this study was to reveal the characteristics of PA and dietary intake of Chinese women in different trimesters as well as the associations between PA and dietary intake. Methods: This is a cross-sectional observational study. PA, dietary intake, and demographics of 1077 Chinese pregnant women were measured. The Chi-square test, Kruskal-Wallis test, multiple logistic regression, and multiple linear regression were used for data analysis. Results: About 57.1% of the participants met the international guideline for PA. Household activity and occupational activity contributed the most to the total PA, while sports/exercise contributed little. The mean energy intake of the participants was 2008 ± 748.0 kcal. Most participants had normal energy intake, but they obtained excessive energy from fat (mean = 41.7 ± 8.7%). PA was not found to be significantly associated with dietary intake. Further, the participants who were unemployed during pregnancy (OR = 0.72, 95% CI: 0.55-0.95; p < 0.05) or had no exercise habits before pregnancy (OR = 0.62, 95% CI: 0.47-0.80; p < 0.01) were less likely to meet the PA guideline. The participants in the third trimester (OR = 1.43, 95% CI: 1.03-1.99; p < 0.05) were more likely to meet the PA guideline compared to those in the first trimester. The older participants (> 30 years) showed higher dietary intake than the younger (< 25 years) participants (p < 0.01). Conclusions: The total PA of Chinese women during pregnancy mostly consists of household and occupational activities, but little sports/exercise. Starting exercise before pregnancy may help women achieve adequate PA during pregnancy. Moreover, these women consumed an excessive amount of fat and their diet intake varies by age., 14 Aug. 2019, 19, 1, Scientific journal, 10.1186/s12884-019-2452-y

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• 日本スポーツ栄養研究誌, (NPO)日本スポーツ栄養学会, 多周波生体電気インピーダンス法を用いた日本人レスリング選手の体水分量推定の妥当性, 塩瀬 圭佑; 近藤 衣美; 山田 陽介; 下山 寛之; 西牧 未央; 山下 大地; 中嶋 耕平; 高橋 英幸; RWL Study Group, Jan. 2019, 12, 107, 107
• Refereed, Archives of Budo, Effects of different periods of rapid weight loss on dehydration and oxidative stress, Mio Nishimaki; Hiroki Tabata; Masayuki Konishi; Stefan Pettersson; Shizuo Sakamoto, © 2018 the Authors. Background and Study Aim: Materials and Methods: Results: Conclusions: Many athletes will lose weight 5% or more within 7 days. Many reports have been published on the negative health effects of rapid weight loss (RWL) in wrestlers. This study aim was the effects of different periods of RWL on dehydration state and oxidative stress. Participants were nine male collegiate wrestlers who reduce their body mass by 5% within short period in randomized order using the same methods. They have experienced 1-day, 3-days and 7-days) weight loss separated by more than 4 weeks. All participants reduced 5% of their body mass in all trials. Following the weight loss, they tried to regain all of their lost weight with an ad libitum diet for 14 h. Body composition and biochemical variables were measured at baseline and immediately after weight loss and weight regain. There were no statistically significant differences in hematocrit, serum sodium, chloride, potassium, calcium, osmotic pressure, and antidiuretic hormone. For plasma aldosterone concentrations and plasma d-ROMs concentrations, two-way analysis of variance revealed the main effect of time (p<0.05). RWL (loss of 5% of body weight within 7 days) is surmised to have increased oxidative stress via dehydration and elevated levels of aldosterone. Although different weight loss periods did not yield any changes, RWL of 5% of body weight was suggested to increase oxidative stress. It is necessary to study the influence of weight loss cycling on athlete’s disease risk in the future., Oct. 2018, 14, 319, 327, Scientific journal

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• Refereed, Food Science and Biotechnology, The Korean Society of Food Science and Technology, Effects of Chios mastic gum and exercise on physical characteristics, blood lipid markers, insulin resistance, and hepatic function in healthy Japanese men, Tomoko Fukazawa; Ilias Smyrnioudis; Masayuki Konishi; Masaki Takahashi; Hyeon Ki Kim; Mio Nishimaki; Mi Xiang; Shizuo Sakamoto, The effects of Chios mastic gum (Pistacia lentiscus var. Chia) and exercise on physical characteristics, blood lipid markers, insulin resistance, and hepatic function were investigated in healthy, non-smoking Japanese men aged ≥ 40 years. Participants were allocated to control (C, 5 g/day placebo powder, n = 7), mastic (M, 5 g/day mastic powder, n = 7), or mastic plus physical activity groups (M + PA, 5 g/day mastic powder and 30-min exercise three times/week, n = 7), and measurements were taken at baseline, 3 and 6 months. Serum triglycerides were significantly reduced at 3 months in M and M + PA compared with C (P & lt  0.05). Serum insulin and homeostatic model assessment of insulin resistance values were significantly reduced at 3 and 6 months in M + PA, and at 6 months in M, compared with C (P & lt  0.05). These results indicate that Chios mastic gum intake for 6 months reduced serum triglyceride and insulin concentrations, and additional exercise enhanced the effect on insulin., 01 Jun. 2018, 27, 3, 773, 780, Scientific journal, 10.1007/s10068-018-0307-3

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• Refereed, Archives of Budo, Effect of obesity-related gene polymorphisms on weight loss of female wrestlers, Mio Nishimaki; Shizuo Sakamoto, 11 Apr. 2018, 14, 117, 123, Scientific journal
• 日本スポーツ栄養研究誌, (NPO)日本スポーツ栄養学会, 全日本選手権出場の男子レスリング選手における減量前体脂肪率と試合に向けた体水分量変化との関連, 近藤 衣美; 山下 大地; 西牧 未央; 荒川 裕志; 相澤 勝治; 中嶋 耕平, Jan. 2018, 11, 119, 119
• Refereed, スポーツ歯学, 中等度強度の持久性運動が唾液中の生化学成分および歯周病原細菌に与える影響, 清水寿男; 田端宏樹; 金鉉基; 西牧未央; 安藤加里菜; 項密; 小西真幸; 坂本静男, Feb. 2017, 20, 2, 1, 6, Scientific journal
• Refereed, 靴の医学, レスリングシューズが女子レスリング選手の外反母趾に及ぼす影響, 西牧未央; 光岡かおり, Feb. 2017, 2, 2, 1, 4, Scientific journal
• Refereed, Journal of Sports Science, Mild Decrease in Skin Temperature Reduces the Heart Rate during Moderate Exercise, Masayuki Konishi; Hiroki Tabata; Karina Ando; Hyeon-Ki Kim; Mio Nishimaki; Mi Xiang; Shizuo Sakamoto, 2017, 5, 305, 312, Scientific journal
• Sports Science in Elite Athlete Support, (独)日本スポーツ振興センター国立スポーツ科学センター, レスリング選手の試合に向けた急速減量後の回復食の摂取状況, 近藤 衣美; 山下 大地; 西牧 未央; 元永 恵子; 山田 陽介; 藤山 光太郎; 中嶋 耕平; 亀井 明子, Nov. 2016, 1, 特別号, 17, 17
• Refereed, British Journal of Sports Medicine, BMJ, P-56 Maximal fat max oxidation and fatmax are not associated with endurance performance in trained runners, Hiroki Tabata; Hyeon-Ki Kim; Masayuki Konishi; Mio Nishimaki; Mi Xiang; Shizuo Sakamoto, Nov. 2016, 50, Suppl 1, A62.2, A63, Scientific journal, 10.1136/bjsports-2016-097120.109

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• Refereed, Journal of Sports Science and Medicine, Effects of Different Intensities of Endurance Exercise in Morning and Evening on the Lipid Metabolism Response, Hyeon-Ki Kim; Karina Ando; Hiroki Tabata; Masayuki Konishi; Masaki Takahashi; Mio Nishimaki; Mi Xiang; Shizuo Sakamoto, 05 Aug. 2016, 15, 467, 476, Scientific journal
• Refereed, Matern Child Health J, Reliability and Validity of a Chinese-Translated Version of a Pregnancy Physical Activity Questionnaire, Mi Xiang; Massayuki Konishi; Huanhuan Hu; Masaki Takahashi; Wenbi Fan; Mio Nishimaki; Karina Ando; Hyeon-Ki Kim; Hiroki Tabata; Takashi Arao; Shizuo Sakamoto, 25 Apr. 2016, 20, 1940, 1947, Scientific journal
• Refereed, Clin Auton Res, Diurnal variation in the diving bradycardia response in young men, Masayuki Konishi; Hiroshi Kawano; Mi Xiang; Hyeon-Ki Kim; Karina Ando; Hiroki Tabata; Mio Nishimaki; Shizuo Sakamoto, 06 Jan. 2016, 26, 135, 140, Scientific journal
• 体力科学, (一社)日本体力医学会, 朝と夕方の異なる運動強度の一過性持久性運動が脂質酸化量に及ぼす影響, 金 鉉基; 安藤 加里菜; 田端 宏樹; 小西 真幸; 西牧 未央; 項 密; 坂本 静男, Dec. 2015, 64, 6, 606, 606
• 体力科学, (一社)日本体力医学会, 皮膚温の2℃低下が運動中の心拍数および主観的運動強度に及ぼす影響の検討, 小西 真幸; 田端 宏樹; 安藤 加里菜; 金 鉉基; 西牧 未央; 項 密; 坂本 静男, Dec. 2015, 64, 6, 648, 648
• 日本臨床スポーツ医学会誌, (一社)日本臨床スポーツ医学会, 安静時の脂質酸化量と運動中の脂質酸化量との関連, 田端 宏樹; 金 鉉基; 遠藤 直哉; 小西 真幸; 安藤 加里菜; 西牧 未央; 項 密; 坂本 静男, Oct. 2015, 23, 4, S191, S191

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• 体力科学, (一社)日本体力医学会, ヒオス島のマスティック摂取と身体活動が生活習慣病関連因子に及ぼす影響, 深澤 朋子; Smyrnioudis Ilias; 小西 真幸; 高橋 将記; 金 鉱基; 安藤 加里菜; 西牧 未央; 項 密; 坂本 静男, Dec. 2014, 63, 6, 700, 700
• 日本臨床スポーツ医学会誌, (一社)日本臨床スポーツ医学会, 朝や夕の最大酸素摂取量および脂質・糖質酸化量の比較, 安藤 加里菜; 金 鉉基; 小西 真幸; 西牧 未央; 田端 宏樹; 項 密; 坂本 静男, Oct. 2014, 22, 4, S204, S204

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• 日本臨床スポーツ医学会誌, (一社)日本臨床スポーツ医学会, 中国人女性と日本人女性の妊娠期における生活習慣の比較, 項 密; 小西 真幸; 安藤 加里菜; 西牧 未央; 金 鉉基; 田端 宏樹; 坂本 静男, Oct. 2014, 22, 4, S209, S209

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• 日本臨床運動療法学会雑誌, (NPO)日本臨床運動療法学会, 朝や夕の一過性運動が糖質・脂質酸化量および主観的疲労度に与える影響, 安藤 加里菜; 金 鉉基; 小西 真幸; 西牧 未央; 田端 宏樹; 項 密; 坂本 静男, Sep. 2014, 16, 1, 50, 50
• Refereed, Jpn. J. Clin. Physiol., The Difference of the Influence between Acute Swimming and Running on Cardiac Fatigue in Young Males, Naoya Endo; Masayuki Konishi; Hyeon Ki Kim; Masaki Takahashi; Mio Nishimaki; Shigeharu Numao; Shizuo Sakamoto, Mar. 2014, 44, 2, 77, 89, Scientific journal
• Refereed, European journal of nutrition, Effect of fluid replacement with green tea on body fluid balance and renal responses under mild thermal hypohydration: a randomized crossover study., Akira Takamata; Ayano Oka; Mayuna Nagata; Natsumi Kosugi; Sayaka Eguchi; Nanako Sakagawa; Aoi Takahashi; Yuki Nishimoto; Mio Nishimaki; Keiko Morimoto; Takanobu Takihara, PURPOSE: Maintaining an appropriate hydration level by ingesting fluid in a hot environment is a measure to prevent heat-related illness. Caffeine-containing beverages, including green tea (GT), have been avoided as inappropriate rehydration beverages to prevent heat-related illness because caffeine has been assumed to exert diuretic/natriuretic action. However, the influence of caffeine intake on urine output in dehydrated individuals is not well documented. The aim of the present study was to examine the effect of fluid replacement with GT on body fluid balance and renal water and electrolyte handling in mildly dehydrated individuals. METHODS: Subjects were dehydrated by performing three bouts of stepping exercise for 20 min separated by 10 min of rest. They were asked to ingest an amount of water (H2O), GT, or caffeinated H2O (20 mg/100 ml; Caf-H2O) that was equal to the volume of fluid loss during the dehydration protocol; fluid balance was measured for 2 h after fluid ingestion. RESULTS: The dehydration protocol induced hypohydration by ~ 10 g/kg body weight (~ 1% of body weight). Fluid balance 2 h after fluid ingestion was significantly less negative in all trials, and the fluid retention ratio was 52.2 ± 4.2% with H2O, 51.0 ± 5.0% with GT, and 47.9 ± 6.2% with Caf-H2O; those values did not differ among the trials. After rehydration, urine output, urine osmolality, and urinary excretions of osmotically active substances, sodium, potassium and chloride were not different among the trials. CONCLUSION: The data indicate that ingestion of GT or an equivalent caffeine amount does not worsen the hydration level 2 h after ingestion and can be effective in reducing the negative fluid balance for acute recovery from mild hypohydration. TRIAL REGISTRATION: ISRCTN53057185; retrospectively registered., 18 Aug. 2023, Scientific journal, True, 10.1007/s00394-023-03236-3

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MISC

• 日本臨床スポーツ医学会誌, 安静時の脂質酸化量と運動中の脂質酸化量との関連, 田端宏樹; 金鉉基; 金鉉基; 遠藤直哉; 小西真幸; 安藤加里菜; 西牧未央; 西牧未央; 項密; 坂本静男, 2015, 23, 4
• 体力科学, 朝と夕方の異なる運動強度の一過性持久性運動が脂質酸化量に及ぼす影響, 金鉉基; 金鉉基; 安藤加里菜; 田端宏樹; 小西真幸; 西牧未央; 西牧未央; 項密; 坂本静男, 2015, 64, 6
• 体力科学, 皮膚温の2°C低下が運動中の心拍数および主観的運動強度に及ぼす影響の検討, 小西真幸; 田端宏樹; 安藤加里菜; 金鉉基; 西牧未央; 項密; 坂本静男, 2015, 64, 6
• スポーツ科学研究, 早稲田大学スポーツ科学学術院, Effects of circadian rhythm and acute endurance exercise on insulin sensitivity, Ando Karina; Kim Hyeon-Ki; Konishi Masayuki; Nishimaki Mio; Tabata Hiroki; Xiang Mi; Sakamoto Shizuo, 2014, 11, 41, 41

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• スポーツ科学研究, 早稲田大学スポーツ科学学術院, Comparison of the effects of acute endurance exercise performed in the morning and evening on High-Molecular-Weight (HMW) adiponectin., Kim Hyeon-Ki; Konishi Masayuki; Tabata Hiroki; Naoya Endo; Ando Karina; Nishimaki Mio; Xiang Mi; Lee Sun-Kyoung; Kim Young-Hak; Sakamoto Shizuo, 2014, 11, 103, 103

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• スポーツ科学研究, 早稲田大学スポーツ科学学術院, Use of the pregnancy physical activity questionnaire (PPAQ) to identify physical activity associated with gestational weight gain during pregnancy, Xiang Mi; Konishi Masayuki; Endo Naoya; Nishimaki Mio; Ando Karina; Kim Hyeon-Ki; Tabata Hiroki; Sakamoto Shizuo, 2014, 11, 42, 42

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• スポーツ科学研究, 早稲田大学スポーツ科学学術院, A correlation between bradycardia during cold face test and heart rate recovery immediately after exercise, Konishi Masayuki; Kim Hyeon-Ki; Ando Karina; Tabata Hiroki; Nishimaki Mio; Xiang Mi; Sakamoto Shizuo, 2014, 11, 63, 63

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• 日本臨床スポーツ医学会誌, 朝や夕の最大酸素摂取量および脂質・糖質酸化量の比較, 安藤加里菜; 金鉉基; 小西真幸; 西牧未央; 田端宏樹; 項密; 坂本静男, 2014, 22, 4
• 日本臨床スポーツ医学会誌, 中国人女性と日本人女性の妊娠期における生活習慣の比較, 項密; 小西真幸; 安藤加里菜; 西牧未央; 金鉉基; 田端宏樹; 坂本静男, 2014, 22, 4
• 日本臨床運動療法学会雑誌, 朝や夕の一過性運動が糖質・脂質酸化量および主観的疲労度に与える影響, 安藤加里菜; 金鉉基; 小西真幸; 西牧未央; 田端宏樹; 項密; 坂本静男, 2014, 16, 1
• 体力科学, ヒオス島のマスティック摂取と身体活動が生活習慣病関連因子に及ぼす影響, 深澤朋子; SMYRNIOUDIS Ilias; 小西真幸; 高橋将記; 金鉱基; 安藤加里菜; 西牧未央; 項密; 坂本静男, 2014, 63, 6
• Not Refereed, 体力科学, (一社)日本体力医学会, ギリシャ・ヒオス島のマスティック摂取が生活習慣病関連因子に及ぼす影響, 深澤朋子; SMYRNIOUDIS Ilias; 小西真幸; 金鉉基; 西牧未央; 田端宏樹; 項密; 坂本静男, Dec. 2015, 64, 6, 611, 611

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• Not Refereed, 日本臨床スポーツ医学会誌, (一社)日本臨床スポーツ医学会, 水泳とランニングにおける一過性長時間運動が脂質代謝に及ぼす影響, 遠藤 直哉; 小西 真幸; 金 鉉基; 西牧 未央; 沼尾 成晴; 坂本 静男, Oct. 2015, 23, 4, S263, S263
• Not Refereed, 日本臨床スポーツ医学会誌, (一社)日本臨床スポーツ医学会, 水泳とランニングの漸増負荷運動中における運動強度による脂質酸化量の比較, 遠藤 直哉; 小西 真幸; 金 鉉基; 高橋 将記; 西牧 未央; 沼尾 成晴; 坂本 静男, Oct. 2014, 22, 4, S151, S151
• Not Refereed, 体育の科学, 特集：コンタクトスポーツの科学 レスリングの医・科学サポート, 山下 大地; 西牧 未央; 西口 茂樹; 和田 貴広; 荒川 裕志, Feb. 2018, 68, 2, 101, 105
• Not Refereed, トレーニング科学, スポーツの現場における栄養学の貢献 : 選手の経験と研究活動から, 西牧 未央, 2018, 30, 1, 3, 6, Introduction scientific journal
• Not Refereed, Research Jounal of Living Science, Effects of rapid weight loss for weight class atheletes, Mio Nishimaki, Mar. 2024, 70, 2, 53, 56

Books etc

• フィットネスチェックハンドブック : 体力測定に基づいたアスリートへの科学的支援, 大修館書店, 日本スポーツ振興センター; ハイパフォーマンススポーツセンター; 国立スポーツ科学センター, 第4章 1-2. 身体組成, Dec. 2020, ix, 389p, 76-80, 9784469269031

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Presentations

• 坂川菜々子; 小杉夏実; 江口紗也香; 高橋葵; 西牧未央; 鷹股亮, 第101回 日本生理学会, The effect of serotonin depletion in the periventricular area and the perifornical area of the lateral hypothalamus on the estrogen-induced modulation of feeding behavior, Poster presentation, Mar. 2024, Mar. 2024, Mar. 2024
• 高橋葵; 小杉夏実; 江口紗也香; 坂川菜々子; 西牧未央; 鷹股亮, 第101回 日本生理学会, Sex differences and effects of sex hormones on high-fat diet preference and body weight regulation, Poster presentation, Mar. 2024, Mar. 2024, Mar. 2024
• 小杉夏実; 江口紗也香; 坂川菜々子; 高橋葵; 西牧未央; 鷹股亮, 第101回 日本生理学会, Effect of estrogen and leptin on palatable sucrose solution intake and energy balance in ovariectomized rats, Poster presentation, Mar. 2024, Mar. 2024, Mar. 2024
• 小杉 夏実; 江口 紗也香; 坂川 菜々子; 高橋 葵; 西牧 未央; 森本 恵子; 鷹股 亮, 第78回 栄養食糧学会大会, 卵巣摘出ラットにおける高嗜好性スクロース溶液摂取とエネルギーバランスに及ぼすエストロゲンとレプチンの影響, 25 May 2024, 24 May 2024, 26 May 2024

Awards

• 優秀演題賞, 女性スポーツ医学研究会, 西牧未央, 相澤勝治, 中嶋耕平, 山下大地, 近藤衣美, 村上富栄, 梶尾安正, Dec. 2017, 中学生レスリング選手の減量に関する実態調査

Research Projects

• 若手研究, Apr. 2019, Mar. 2023, 19K18656, 月経周期を考慮した体重階級制アスリートにおける減量法の確立, 西牧 未央, 日本学術振興会, 科学研究費助成事業, 4290000, 3300000, 990000, レスリングなどの体重階級制競技選手の多くは、試合前の計量にて規定体重を下回る必要があるため、食事制限、水分制限を用いて減量をおこなう。女性アスリートのウェイトコントロールは、周期的に性ホルモン濃度が増減する月経周期を考慮して取り組むべきである。しかし、脱水を主とした急速減量と月経周期の関係は明らかとなっていない。そこで本研究は、脱水を主とした急速減量によって引き起こされる性ホルモン応答、体内水分量および血中電解質濃度の動態を明らかにし、体重階級制女性アスリートの最適な減量方法を確立することを目的とし、本課題を実施した。 女子レスリング選手を対象に実施した調査では、「女性アスリートのコンディショニングに関する調査」において、コンディションに関する知識に興味がありますかという問いに対して、関心があると答えた項目は、体組成、月経周期、月経異常の順に多かった。さらに、月経によって（黄体期が減量期間と重なったため）体重が落ちにくいと感じたことはありますかとの問いに過半数の女子レスリング選手が「はい」と回答した。審美系の種目と比較して、階級制種目のアスリートの月経異常の発生率は低い体重階級制競技種目であるが、年間4～5回の脱水を主とした急速減量を繰り返していることが報告されているにも関わらず、女性体重階級制アスリートを対象とした研究は非常に少ないのが現状である。月経周期に伴う体重変動の要因は体水分量の変化が関与していることが考えられ、黄体期に増加するホルモンが影響していることが報告されている(Stachenfeld et al, 2008)。性ホルモンであるエストロゲン、プロゲステロンは、体水分貯留を高める作用があることが報告されており(Stachenfeld et al, 2005)、体水分量の増加に伴い卵胞期に比べて黄体期に体重が増加する可能性が考えられる。, kaken

  対象リソースIRI
• Grant-in-Aid for Young Scientists (B), Apr. 2016, Mar. 2020, 16K21685, Effects of rapid weight loss on body water and electrolyte control, and oxidative stress for weight class athletes, Nishimaki Mio, Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), National Agency for the Advancement of Sports and Health, 3640000, 2800000, 840000, Many reports have been published on the negative health effects of rapid weight loss (RWL) in wrestlers. This study aim was the effects of different periods of RWL on dehydration state and oxidative stress.Participants were nine male collegiate wrestlers who reduce their body mass by 5% within short period in randomized order using the same methods. They have experienced 1-day, 3-days and 7-days) weight loss separated by more than 4 weeks. All participants reduced 5% of their body mass in all trials. Following the weight loss, they tried to regain all of their lost weight with an ad libitum diet for 14 h. Body composition and biochemical variables were measured at baseline and immediately after weight loss and weight regain.For plasma aldosterone concentrations and plasma d-ROMs concentrations, two-way analysis of variance revealed the main effect of time (p<0.05). RWL is surmised to have increased oxidative stress via dehydration and elevated levels of aldosterone., kaken

  対象リソースIRI
• Apr. 2014, Mar. 2015, 異なる急速減量の期間が生体内の酸化ストレス応答に及ぼす影響について, 西牧 未央, 公益財団法人ヤマハ発動機スポーツ振興財団
• 基盤研究(C), Apr. 2022, Mar. 2026, 22K11593, 女性アスリートによる急速減量の繰り返しが性ホルモン及びタンパク質代謝に及ぼす影響, 西牧 未央, 日本学術振興会, 科学研究費助成事業 基盤研究(C), 奈良女子大学, 4160000, 3200000, 960000, kaken

  対象リソースIRI
• Jul. 2023, Mar. 2024, Principal investigator, 摂食制限による急速な体重減少が生殖機能と摂食制限解除後の摂食行動に及ぼす影響の性差, 奈良女子大学, 研究推進プロジェクト経費, 摂食制限による急速な体重減少が生殖機能と摂食制限解除後の摂食行動に及ぼす影響の性差